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The map label for this gene is degQ [C]

Identifier: 78778479

GI number: 78778479

Start: 96830

End: 97951

Strand: Reverse

Name: degQ [C]

Synonym: PMT9312_0094

Alternate gene names: 78778479

Gene position: 97951-96830 (Counterclockwise)

Preceding gene: 78778483

Following gene: 78778477

Centisome position: 5.73

GC content: 31.46

Gene sequence:

>1122_bases
TTGAAACTTTACAGACACAAGAAGTTATTATTCTCCTCAGCAATCACAATTGGTATTATATGTCCTTCAAATATAATATC
TGGACCATTAACTAATCCAAGATTTAATGAAAATAATACGTATTCACACAAATCATTCATAACTAAAGCTGTAGAAAAAA
CTGGTTCTTCTGTTGTGACAATTGATACTCAAAGATATATTAAAAAAAGAAAGTTTCCAAAAAATTCTCAACTATTTATA
GACCCATATTTTGAAAGATTTTTTGGATTAGACTTACCTAACGATAATCAGCCAAGGATAGAGCAAAACCAAGGAAGTGG
GTTTATATTCGCAGACGGACTTGTAATGACTAATGCTCATGTTGTAAATGAATCGGATAAGGTAATTGTTGGTTTAACCA
ATGGGGAAAAATTAAAAGCAAAACTCATAGGGCAAGACTTTTTTACTGATTTAGCTGTGCTCAAGATTGAAGGGAAAGGG
CCTTGGCCAAAAGCAAAGTTGGGCGATTCAGCAAAAATTAAAGTTGGTGATTGGGCAATCGCAGTAGGAAATCCATTCGG
ACTGGAAAACACAGTTACACTTGGTATTATCAGCAATATAAAAAGAAACGTCACTCAACTAGGAATATACGATAAAAAAC
TTGAGTTAATTCAAACTGATGCTGCTATCAATCCCGGAAATTCAGGAGGTCCACTACTGAATAGTAATGGAGAAGTAATT
GGTATTAATACCTTGATCAGATCAGGTCCAGGAGCAGGTTTAAGTTTCGCAATCCCAATTAATAAAGCCAAGGAAATTGC
ATATCAGCTAATAAATAATGGAAAAGTAATACATCCTATGATTGGTATAAGCCTAATAGATGACAGTAATTCTGAAACAA
ATAATAGTTCCGTAAAAGTTGGTTATGTAGTACCAAATAGTCCAGCTGAAAAGAGTGGAATCAAAGTAAATGACATAATC
ATAAAAGTGGGTAATAAAAATATTCAGAAAGTTTCAGATGTTATTAACCAAATAACTAAAAATGGTATTAATAAACAAAT
AAAAATATTATTGAAACGTAGAAATAAATTTATTATGTTAAAAGTAATACCAACTGATATTACTAATCTACAAAATAACT
AA

Upstream 100 bases:

>100_bases
AAATTTTTCTCTGAACTATATAAATTTTTTTTAGTAGTTATATTAAAACTACATAAATAATGTGTATTTAATTCATTCAT
AGAATATAAAAAAATCAAAA

Downstream 100 bases:

>100_bases
AAGTTTCAAACGTCATTCTCTTTAAGTATTTCCACACATCTAGAAATACAATTACCATCTTTTATATCACAGGTTGAAAT
GCATTCGAAATAACTTTCAA

Product: PDZ/DHR/GLGF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKLYRHKKLLFSSAITIGIICPSNIISGPLTNPRFNENNTYSHKSFITKAVEKTGSSVVTIDTQRYIKKRKFPKNSQLFI
DPYFERFFGLDLPNDNQPRIEQNQGSGFIFADGLVMTNAHVVNESDKVIVGLTNGEKLKAKLIGQDFFTDLAVLKIEGKG
PWPKAKLGDSAKIKVGDWAIAVGNPFGLENTVTLGIISNIKRNVTQLGIYDKKLELIQTDAAINPGNSGGPLLNSNGEVI
GINTLIRSGPGAGLSFAIPINKAKEIAYQLINNGKVIHPMIGISLIDDSNSETNNSSVKVGYVVPNSPAEKSGIKVNDII
IKVGNKNIQKVSDVINQITKNGINKQIKILLKRRNKFIMLKVIPTDITNLQNN

Sequences:

>Translated_373_residues
MKLYRHKKLLFSSAITIGIICPSNIISGPLTNPRFNENNTYSHKSFITKAVEKTGSSVVTIDTQRYIKKRKFPKNSQLFI
DPYFERFFGLDLPNDNQPRIEQNQGSGFIFADGLVMTNAHVVNESDKVIVGLTNGEKLKAKLIGQDFFTDLAVLKIEGKG
PWPKAKLGDSAKIKVGDWAIAVGNPFGLENTVTLGIISNIKRNVTQLGIYDKKLELIQTDAAINPGNSGGPLLNSNGEVI
GINTLIRSGPGAGLSFAIPINKAKEIAYQLINNGKVIHPMIGISLIDDSNSETNNSSVKVGYVVPNSPAEKSGIKVNDII
IKVGNKNIQKVSDVINQITKNGINKQIKILLKRRNKFIMLKVIPTDITNLQNN
>Mature_373_residues
MKLYRHKKLLFSSAITIGIICPSNIISGPLTNPRFNENNTYSHKSFITKAVEKTGSSVVTIDTQRYIKKRKFPKNSQLFI
DPYFERFFGLDLPNDNQPRIEQNQGSGFIFADGLVMTNAHVVNESDKVIVGLTNGEKLKAKLIGQDFFTDLAVLKIEGKG
PWPKAKLGDSAKIKVGDWAIAVGNPFGLENTVTLGIISNIKRNVTQLGIYDKKLELIQTDAAINPGNSGGPLLNSNGEVI
GINTLIRSGPGAGLSFAIPINKAKEIAYQLINNGKVIHPMIGISLIDDSNSETNNSSVKVGYVVPNSPAEKSGIKVNDII
IKVGNKNIQKVSDVINQITKNGINKQIKILLKRRNKFIMLKVIPTDITNLQNN

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=350, Percent_Identity=36, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI7019477, Length=338, Percent_Identity=34.3195266272189, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI22129776, Length=358, Percent_Identity=33.7988826815642, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI24308541, Length=281, Percent_Identity=34.1637010676157, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1789629, Length=324, Percent_Identity=37.3456790123457, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786356, Length=343, Percent_Identity=34.6938775510204, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789630, Length=287, Percent_Identity=37.9790940766551, Blast_Score=153, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24646839, Length=309, Percent_Identity=34.6278317152104, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 40846; Mature: 40846

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYRHKKLLFSSAITIGIICPSNIISGPLTNPRFNENNTYSHKSFITKAVEKTGSSVVT
CCCHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
IDTQRYIKKRKFPKNSQLFIDPYFERFFGLDLPNDNQPRIEQNQGSGFIFADGLVMTNAH
EEHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCCCEECCCCCEEEEECCEEEECEE
VVNESDKVIVGLTNGEKLKAKLIGQDFFTDLAVLKIEGKGPWPKAKLGDSAKIKVGDWAI
EECCCCCEEEEECCCCEEEEEECCHHHHCCEEEEEEECCCCCCCCCCCCCCEEEECCEEE
AVGNPFGLENTVTLGIISNIKRNVTQLGIYDKKLELIQTDAAINPGNSGGPLLNSNGEVI
EECCCCCCCCEEEEEEHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCEECCCCCEE
GINTLIRSGPGAGLSFAIPINKAKEIAYQLINNGKVIHPMIGISLIDDSNSETNNSSVKV
EEEHEEECCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCEEEE
GYVVPNSPAEKSGIKVNDIIIKVGNKNIQKVSDVINQITKNGINKQIKILLKRRNKFIML
EEEECCCCCHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHEECCCCEEEE
KVIPTDITNLQNN
EEECCCCCCCCCC
>Mature Secondary Structure
MKLYRHKKLLFSSAITIGIICPSNIISGPLTNPRFNENNTYSHKSFITKAVEKTGSSVVT
CCCHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
IDTQRYIKKRKFPKNSQLFIDPYFERFFGLDLPNDNQPRIEQNQGSGFIFADGLVMTNAH
EEHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCCCEECCCCCEEEEECCEEEECEE
VVNESDKVIVGLTNGEKLKAKLIGQDFFTDLAVLKIEGKGPWPKAKLGDSAKIKVGDWAI
EECCCCCEEEEECCCCEEEEEECCHHHHCCEEEEEEECCCCCCCCCCCCCCEEEECCEEE
AVGNPFGLENTVTLGIISNIKRNVTQLGIYDKKLELIQTDAAINPGNSGGPLLNSNGEVI
EECCCCCCCCEEEEEEHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCEECCCCCEE
GINTLIRSGPGAGLSFAIPINKAKEIAYQLINNGKVIHPMIGISLIDDSNSETNNSSVKV
EEEHEEECCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCEEEE
GYVVPNSPAEKSGIKVNDIIIKVGNKNIQKVSDVINQITKNGINKQIKILLKRRNKFIML
EEEECCCCCHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHEECCCCEEEE
KVIPTDITNLQNN
EEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA