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The map label for this gene is cysH [H]

Identifier: 78778469

GI number: 78778469

Start: 87637

End: 88362

Strand: Reverse

Name: cysH [H]

Synonym: PMT9312_0084

Alternate gene names: 78778469

Gene position: 88362-87637 (Counterclockwise)

Preceding gene: 78778474

Following gene: 78778468

Centisome position: 5.17

GC content: 31.13

Gene sequence:

>726_bases
ATGATTGAAAACATCCAAAAAGATATTCAACCTGAATTAATAAATAAATATAATCAAGAGCTAAGAGATATGACTGCTCA
AGAAATGCTTACATGGGGTTATAAAGAGTTTGATAATCAATTCGCAATTACAACAAGTTTTGGTATACAGTCATCAGTCC
TTTTAAATATGGTCAGTAAATTATGTCTACAAAAAAAAATCAAAATATTTTGGATAGATACAGGTTATTTACCTCCAGAA
ACATACCATTATGCTGAAAAACTTATTGTCGATTTATCTTTAGAAATAGAAGTTCTGCAAAGTGAATTATCCCCAGCAAG
AATGGAGACTATACACGGAAAACTTTGGGAAACAAATAAAGCGAGTGATTTAGATAAGTATCATGATTTGAGAAAGATAA
AACCTTTGGAAAATGGTCTAGAAAAATATAAAATTAACTGTTGGGCAAGCGGTGTTAGATCAAGCCAAACAGAAAATAGA
AAAGAAATGAAATTCTTGGACCTAATTCGTCAAAGACTTTCTCTAAGGCCTTTATTAAATTGGACAAATAAAGATATTTT
TTATTATATGAAAGAGAATAATTTACCTGCCCATCCACTTTTCAGCAAAGGTTATTCTACTGTAGGTGATTGGCACTCAA
GCACTCCTGATGGTAATAAAACAAAAGGAAGAGCAACAAGATTTGGGGGGATTAAACAAGAGTGTGGAATACACACTAAT
AATTAA

Upstream 100 bases:

>100_bases
TTCATTAGCGAAATATTGTTATCCATAAATGTATTATTAAATAATACGAAGAATTTTCAAATTAAGTGAAATAACATTCA
TCTCATAACCAACTTTAAGA

Downstream 100 bases:

>100_bases
ATTGATCATAAAAAAATGATCTCAGATACAAATTTTTTATTAGTGGGCAATAGTAGGCTTCATTGGGCTAAATATTCTAA
AAATCAATCTAAATTCTTCC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIENIQKDIQPELINKYNQELRDMTAQEMLTWGYKEFDNQFAITTSFGIQSSVLLNMVSKLCLQKKIKIFWIDTGYLPPE
TYHYAEKLIVDLSLEIEVLQSELSPARMETIHGKLWETNKASDLDKYHDLRKIKPLENGLEKYKINCWASGVRSSQTENR
KEMKFLDLIRQRLSLRPLLNWTNKDIFYYMKENNLPAHPLFSKGYSTVGDWHSSTPDGNKTKGRATRFGGIKQECGIHTN
N

Sequences:

>Translated_241_residues
MIENIQKDIQPELINKYNQELRDMTAQEMLTWGYKEFDNQFAITTSFGIQSSVLLNMVSKLCLQKKIKIFWIDTGYLPPE
TYHYAEKLIVDLSLEIEVLQSELSPARMETIHGKLWETNKASDLDKYHDLRKIKPLENGLEKYKINCWASGVRSSQTENR
KEMKFLDLIRQRLSLRPLLNWTNKDIFYYMKENNLPAHPLFSKGYSTVGDWHSSTPDGNKTKGRATRFGGIKQECGIHTN
N
>Mature_241_residues
MIENIQKDIQPELINKYNQELRDMTAQEMLTWGYKEFDNQFAITTSFGIQSSVLLNMVSKLCLQKKIKIFWIDTGYLPPE
TYHYAEKLIVDLSLEIEVLQSELSPARMETIHGKLWETNKASDLDKYHDLRKIKPLENGLEKYKINCWASGVRSSQTENR
KEMKFLDLIRQRLSLRPLLNWTNKDIFYYMKENNLPAHPLFSKGYSTVGDWHSSTPDGNKTKGRATRFGGIKQECGIHTN
N

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=221, Percent_Identity=32.579185520362, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325425, Length=249, Percent_Identity=30.1204819277108, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 28114; Mature: 28114

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENIQKDIQPELINKYNQELRDMTAQEMLTWGYKEFDNQFAITTSFGIQSSVLLNMVSK
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LCLQKKIKIFWIDTGYLPPETYHYAEKLIVDLSLEIEVLQSELSPARMETIHGKLWETNK
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
ASDLDKYHDLRKIKPLENGLEKYKINCWASGVRSSQTENRKEMKFLDLIRQRLSLRPLLN
CCHHHHHHHHHHHCHHHHHHHHEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
WTNKDIFYYMKENNLPAHPLFSKGYSTVGDWHSSTPDGNKTKGRATRFGGIKQECGIHTN
CCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCC
N
C
>Mature Secondary Structure
MIENIQKDIQPELINKYNQELRDMTAQEMLTWGYKEFDNQFAITTSFGIQSSVLLNMVSK
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LCLQKKIKIFWIDTGYLPPETYHYAEKLIVDLSLEIEVLQSELSPARMETIHGKLWETNK
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
ASDLDKYHDLRKIKPLENGLEKYKINCWASGVRSSQTENRKEMKFLDLIRQRLSLRPLLN
CCHHHHHHHHHHHCHHHHHHHHEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
WTNKDIFYYMKENNLPAHPLFSKGYSTVGDWHSSTPDGNKTKGRATRFGGIKQECGIHTN
CCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1463852 [H]