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The map label for this gene is coaE

Identifier: 78778435

GI number: 78778435

Start: 53900

End: 54517

Strand: Reverse

Name: coaE

Synonym: PMT9312_0050

Alternate gene names: 78778435

Gene position: 54517-53900 (Counterclockwise)

Preceding gene: 78778437

Following gene: 78778433

Centisome position: 3.19

GC content: 25.08

Gene sequence:

>618_bases
ATGGATGTTCTTCAAAAATTAAAAAATAACCAAAGAAGAATTGGTTTAACAGGAGGTATTGCCAGTGGGAAGTCAACAAT
AACGAATTATATTAGAAAACATAAAAACATTCCAATATTAGATGCAGATAATTTATCAAGAGAATTAATTAAACCAAACA
CATATGGATATAAAAAAATTTTAGATTATTTTGGAAATCAAATTATTGATACTAAGAACAATTCAGAAAAAGCAATAAAC
AGAAAACTTTTAAGAAACATTATTTTTAAACATTCAGAAAGTAAAGAATGGATTGACAACCTGCTTCACCCCTTAGTTAA
AGAAAAAATGATAGAAGAATGCATTCAATACAAAAATAATCAAACTATAGTATTGGTTATTCCATTATTATTTGAAGCAA
AATTTGAAGATATTTGCACTGAAATATGGTTAGTTAAATGTCCTAGAGAACTTCAAAAAAAAAGACTTATCACACGAGAT
AAAATTAGCGAAAAAGAAGCATATGAAACAATAAATCTTCAATTAAGTTTTGAAGAAAAAAGTAAATTTTCAGATATTAT
TTTAGATAATTCAGATGACCAAAATAAATGGATCAACACGATTAGAGAAATTCTTTGA

Upstream 100 bases:

>100_bases
CAAGTGGAATCAGACTGGCTCAATCTCTTTTAATATTTTTAATTCATACTAACTTCTCTTTAATACTAAAGAAACAGGTA
ATTAGATTATTATTAAAAAT

Downstream 100 bases:

>100_bases
AGCTTTAGCCATTCAACTTTTCTGCAAGAAGTTTATTTGCAAGTTTAGGGTCAGCTTTACCTTTAGTTCTTTTCATAAGT
TGACCAATAAAAAAACCAAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MDVLQKLKNNQRRIGLTGGIASGKSTITNYIRKHKNIPILDADNLSRELIKPNTYGYKKILDYFGNQIIDTKNNSEKAIN
RKLLRNIIFKHSESKEWIDNLLHPLVKEKMIEECIQYKNNQTIVLVIPLLFEAKFEDICTEIWLVKCPRELQKKRLITRD
KISEKEAYETINLQLSFEEKSKFSDIILDNSDDQNKWINTIREIL

Sequences:

>Translated_205_residues
MDVLQKLKNNQRRIGLTGGIASGKSTITNYIRKHKNIPILDADNLSRELIKPNTYGYKKILDYFGNQIIDTKNNSEKAIN
RKLLRNIIFKHSESKEWIDNLLHPLVKEKMIEECIQYKNNQTIVLVIPLLFEAKFEDICTEIWLVKCPRELQKKRLITRD
KISEKEAYETINLQLSFEEKSKFSDIILDNSDDQNKWINTIREIL
>Mature_205_residues
MDVLQKLKNNQRRIGLTGGIASGKSTITNYIRKHKNIPILDADNLSRELIKPNTYGYKKILDYFGNQIIDTKNNSEKAIN
RKLLRNIIFKHSESKEWIDNLLHPLVKEKMIEECIQYKNNQTIVLVIPLLFEAKFEDICTEIWLVKCPRELQKKRLITRD
KISEKEAYETINLQLSFEEKSKFSDIILDNSDDQNKWINTIREIL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=195, Percent_Identity=30.2564102564103, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI191252795, Length=195, Percent_Identity=30.2564102564103, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI110227607, Length=179, Percent_Identity=25.6983240223464, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI110227605, Length=179, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI110227603, Length=179, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI110227601, Length=179, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI205277394, Length=179, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786292, Length=177, Percent_Identity=30.5084745762712, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=31.25, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25143409, Length=175, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320402, Length=180, Percent_Identity=37.2222222222222, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24644728, Length=180, Percent_Identity=32.2222222222222, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658602, Length=185, Percent_Identity=27.027027027027, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_PROM9 (Q31DD4)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_396547.1
- ProteinModelPortal:   Q31DD4
- SMR:   Q31DD4
- STRING:   Q31DD4
- GeneID:   3764831
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_0050
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- ProtClustDB:   PRK14730
- BioCyc:   PMAR74546:PMT9312_0050-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 24149; Mature: 24149

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS51219 DPCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLQKLKNNQRRIGLTGGIASGKSTITNYIRKHKNIPILDADNLSRELIKPNTYGYKKI
CCHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHCCCCCCHHHH
LDYFGNQIIDTKNNSEKAINRKLLRNIIFKHSESKEWIDNLLHPLVKEKMIEECIQYKNN
HHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QTIVLVIPLLFEAKFEDICTEIWLVKCPRELQKKRLITRDKISEKEAYETINLQLSFEEK
CEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHH
SKFSDIILDNSDDQNKWINTIREIL
HHHHHHEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MDVLQKLKNNQRRIGLTGGIASGKSTITNYIRKHKNIPILDADNLSRELIKPNTYGYKKI
CCHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHCCCCCCHHHH
LDYFGNQIIDTKNNSEKAINRKLLRNIIFKHSESKEWIDNLLHPLVKEKMIEECIQYKNN
HHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QTIVLVIPLLFEAKFEDICTEIWLVKCPRELQKKRLITRDKISEKEAYETINLQLSFEEK
CEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHH
SKFSDIILDNSDDQNKWINTIREIL
HHHHHHEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA