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The map label for this gene is zupT [H]

Identifier: 78358594

GI number: 78358594

Start: 3515696

End: 3516511

Strand: Reverse

Name: zupT [H]

Synonym: Dde_3555

Alternate gene names: 78358594

Gene position: 3516511-3515696 (Counterclockwise)

Preceding gene: 78358595

Following gene: 78358588

Centisome position: 94.27

GC content: 54.9

Gene sequence:

>816_bases
ATGTTTGCTACCCAAGATATTCTGTTCGCCTTCGGCCTGACGCTGTTTGCCGGTCTGTGTACCGGCATCGGCAGCGCTCT
GGCGTTTTTTACCCAGAAAACCAATACAAAGGTGCTGTCTGTGGCACTGGGGTTTTCGGCGGGTGTCATGCTGTACGTTT
CTTTTGTGGAAATTCTGTCCAAAGCGCAGGATGCCCTGACGGCATCTCTGGGCAATGTGGCTGGTGCGTGGGCAACTGTG
GCTTCGTTTTTCGGGGGCATCGGGTTCATTGCGCTTATCGACTATTTCGTGCCGTCGGAAGAAAACCCCCACGAGGTGCA
GAAAGTTGAGGCCATGGACGACCAATGTGAGGCAGCGCGTTTTAAAAAGCTGTACCGCATGGGAATCTTCACTGCCCTTG
CCATCGGCATTCACAACTTTCCCGAAGGGCTGGCAACGTTTACAGCGGCCCTGACCGATCCCCAGCTGGGTGTGGCCATT
GCCGTGGCCATTGCCATTCACAACATACCGGAAGGCATTGCTGTCTCCATACCCGTCTTTTATGCCACCGGTGACCGCAG
GCTGGCGTTCAGGCTGTCGTTTCTGTCGGGGCTTTCAGAACCTGTGGGCGCGCTGGTGGGCTATCTGCTGCTGATGCCGT
TTTTTTCAGATACGGTCTTCGGCGTGCTGTTTGCGGGTGTTGCAGGTATAATGGTGTTCATTTCGCTGGATGAACTGCTG
CCTACGGCAAAGGAATACGGCGAGCATCATCTTTCCATTGCCGGTGTTGTGGCCGGTATGGCTGTTATGGCGCTCAGCCT
GCTGCTGTTTATCTGA

Upstream 100 bases:

>100_bases
GCAGAACTCCCGCCCGTGATGTAGTGTGTTTATTCTTGCTCTGAGGCGCATATCTGGTATTGTTTCAGACTGATATCTCT
ACCTGTGCCAGGAGCTGAAA

Downstream 100 bases:

>100_bases
TTGCGGTGGCGGACCGTTGCAGAAAAGCCCCCGCAAGGGGGCTTTGTGTTTGCTGCAGACCGGCCCTGTAAACCGTACCG
GCCATTCTGCGGGCCTGCGG

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MFATQDILFAFGLTLFAGLCTGIGSALAFFTQKTNTKVLSVALGFSAGVMLYVSFVEILSKAQDALTASLGNVAGAWATV
ASFFGGIGFIALIDYFVPSEENPHEVQKVEAMDDQCEAARFKKLYRMGIFTALAIGIHNFPEGLATFTAALTDPQLGVAI
AVAIAIHNIPEGIAVSIPVFYATGDRRLAFRLSFLSGLSEPVGALVGYLLLMPFFSDTVFGVLFAGVAGIMVFISLDELL
PTAKEYGEHHLSIAGVVAGMAVMALSLLLFI

Sequences:

>Translated_271_residues
MFATQDILFAFGLTLFAGLCTGIGSALAFFTQKTNTKVLSVALGFSAGVMLYVSFVEILSKAQDALTASLGNVAGAWATV
ASFFGGIGFIALIDYFVPSEENPHEVQKVEAMDDQCEAARFKKLYRMGIFTALAIGIHNFPEGLATFTAALTDPQLGVAI
AVAIAIHNIPEGIAVSIPVFYATGDRRLAFRLSFLSGLSEPVGALVGYLLLMPFFSDTVFGVLFAGVAGIMVFISLDELL
PTAKEYGEHHLSIAGVVAGMAVMALSLLLFI
>Mature_271_residues
MFATQDILFAFGLTLFAGLCTGIGSALAFFTQKTNTKVLSVALGFSAGVMLYVSFVEILSKAQDALTASLGNVAGAWATV
ASFFGGIGFIALIDYFVPSEENPHEVQKVEAMDDQCEAARFKKLYRMGIFTALAIGIHNFPEGLATFTAALTDPQLGVAI
AVAIAIHNIPEGIAVSIPVFYATGDRRLAFRLSFLSGLSEPVGALVGYLLLMPFFSDTVFGVLFAGVAGIMVFISLDELL
PTAKEYGEHHLSIAGVVAGMAVMALSLLLFI

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=322, Percent_Identity=27.0186335403727, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI229577422, Length=329, Percent_Identity=26.4437689969605, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789419, Length=258, Percent_Identity=38.3720930232558, Blast_Score=150, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17507805, Length=298, Percent_Identity=27.1812080536913, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24652846, Length=175, Percent_Identity=29.1428571428571, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28653; Mature: 28653

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFATQDILFAFGLTLFAGLCTGIGSALAFFTQKTNTKVLSVALGFSAGVMLYVSFVEILS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHH
KAQDALTASLGNVAGAWATVASFFGGIGFIALIDYFVPSEENPHEVQKVEAMDDQCEAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FKKLYRMGIFTALAIGIHNFPEGLATFTAALTDPQLGVAIAVAIAIHNIPEGIAVSIPVF
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
YATGDRRLAFRLSFLSGLSEPVGALVGYLLLMPFFSDTVFGVLFAGVAGIMVFISLDELL
EECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PTAKEYGEHHLSIAGVVAGMAVMALSLLLFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFATQDILFAFGLTLFAGLCTGIGSALAFFTQKTNTKVLSVALGFSAGVMLYVSFVEILS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHH
KAQDALTASLGNVAGAWATVASFFGGIGFIALIDYFVPSEENPHEVQKVEAMDDQCEAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FKKLYRMGIFTALAIGIHNFPEGLATFTAALTDPQLGVAIAVAIAIHNIPEGIAVSIPVF
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
YATGDRRLAFRLSFLSGLSEPVGALVGYLLLMPFFSDTVFGVLFAGVAGIMVFISLDELL
EECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PTAKEYGEHHLSIAGVVAGMAVMALSLLLFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA