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The map label for this gene is trpB [H]

Identifier: 78358518

GI number: 78358518

Start: 3439750

End: 3440913

Strand: Reverse

Name: trpB [H]

Synonym: Dde_3479

Alternate gene names: 78358518

Gene position: 3440913-3439750 (Counterclockwise)

Preceding gene: 78358519

Following gene: 78358517

Centisome position: 92.24

GC content: 62.11

Gene sequence:

>1164_bases
ATGAAAAAAGGGTATTTTGGTGATTTCGGCGGGCAGTTTGTACCCGAACTGCTCATGCCGCCGCTGAAGGAATTGGAAAA
TGCGCTGGAAACCGTGGTGCCTTCACCTGAGTTTCAGAATGAGTTCCACATGCTGCTGCGCGAATATGTGGGCCGCGAAA
CGCCGCTCACCCTGTGCCGCAGGCTGTCTGCCGAGCTCGGGTTCAATCTGTGGCTCAAGCGTGAGGACCTGGCGCACAGC
GGATCGCATAAAATAAACAACACGCTGGGGCAGGCGCTGCTGACAAAGCATATGGGCAAGCCGGCCATGCTGGCGGAGAC
AGGTGCAGGTCAGCATGGCGTGGCCACGGCCACGGCCGCCGCCGCTCTGGGGCTGGAATGTGTGGTCTTTATGGGCGCCG
TGGACGTGGAGCGTCAGGCGCTCAATGTGGAACGCATGCGCCTGCTGGGGGCCGAGGTGGTGCCCGTGCAGAGCGGCACC
CGCACCCTCAAGGATGCCATCAACGAAGCCATGCGTTTCTGGATAGCCAATATTGCCACGCACCATTACTGCTTCGGCAC
GGCGGCGGGGCCGCATCCTTTTCCCACGCTGGTGCGCGACCTGCAGTCCGTCATAGGGCGCGAGGCACGCAGGCAGATTC
TGGAAAAAACAGGCAGGCTGCCCCATATGGTGGTGGCATGCGTGGGCGGCGGTTCCAACGCCATCGGCGCATTCCATGCC
TTTATTCCCGACGGGCAGGTACAGCTTGTGGGGGTTGAGGCTGCAGGCAGCGGAGAACCGGGCTGCTACAATTCTGCGCC
CATCAATCTGGGTACTCCCGGCGTGCTGCACGGCAACCATACCATGCTGCTGCAGAGTGCCGACGGGCAGATACTTCCCT
CGCATTCGGTTGCTGCCGGACTGGACTACCCCGGCGTGGGGCCGGAACATGCAGCTCTGGGCCGCAGCGGCAGAGCGCGG
TACGGCATGGTGAACGATGCGCAGGCGCTGCATGCGTTTAAAACGCTTTCGCGCATGGAGGGCATCATACCGGCGCTGGA
AAGCTCGCACGCCGTGGCGTGGGTGCTGGAAAACCGCGACGGGATTCCCCGCGGGGCCGATGTGGTCGTCAACCTGTCCG
GTCGTGGCGACAAGGACATGGGCATCATCAACAACCTGCTGTAA

Upstream 100 bases:

>100_bases
TCGCCCCATGTAGGGCGGTGATGTCTCTCCTGCGGCGGCGGGTGTCCGGCGGCTTCTGCACTGTGCGGTGCGCAATGCAC
CGGCAGAACAAGGACTGGAC

Downstream 100 bases:

>100_bases
AAGGGGAACACACCATGCATACAGAACATATCACAAGCCCCGCAGACAGGCTGACCATGCGTATCCGCGAGGCCAACCGT
CAGGGCCGCAAGGCTCTTAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKKGYFGDFGGQFVPELLMPPLKELENALETVVPSPEFQNEFHMLLREYVGRETPLTLCRRLSAELGFNLWLKREDLAHS
GSHKINNTLGQALLTKHMGKPAMLAETGAGQHGVATATAAAALGLECVVFMGAVDVERQALNVERMRLLGAEVVPVQSGT
RTLKDAINEAMRFWIANIATHHYCFGTAAGPHPFPTLVRDLQSVIGREARRQILEKTGRLPHMVVACVGGGSNAIGAFHA
FIPDGQVQLVGVEAAGSGEPGCYNSAPINLGTPGVLHGNHTMLLQSADGQILPSHSVAAGLDYPGVGPEHAALGRSGRAR
YGMVNDAQALHAFKTLSRMEGIIPALESSHAVAWVLENRDGIPRGADVVVNLSGRGDKDMGIINNLL

Sequences:

>Translated_387_residues
MKKGYFGDFGGQFVPELLMPPLKELENALETVVPSPEFQNEFHMLLREYVGRETPLTLCRRLSAELGFNLWLKREDLAHS
GSHKINNTLGQALLTKHMGKPAMLAETGAGQHGVATATAAAALGLECVVFMGAVDVERQALNVERMRLLGAEVVPVQSGT
RTLKDAINEAMRFWIANIATHHYCFGTAAGPHPFPTLVRDLQSVIGREARRQILEKTGRLPHMVVACVGGGSNAIGAFHA
FIPDGQVQLVGVEAAGSGEPGCYNSAPINLGTPGVLHGNHTMLLQSADGQILPSHSVAAGLDYPGVGPEHAALGRSGRAR
YGMVNDAQALHAFKTLSRMEGIIPALESSHAVAWVLENRDGIPRGADVVVNLSGRGDKDMGIINNLL
>Mature_387_residues
MKKGYFGDFGGQFVPELLMPPLKELENALETVVPSPEFQNEFHMLLREYVGRETPLTLCRRLSAELGFNLWLKREDLAHS
GSHKINNTLGQALLTKHMGKPAMLAETGAGQHGVATATAAAALGLECVVFMGAVDVERQALNVERMRLLGAEVVPVQSGT
RTLKDAINEAMRFWIANIATHHYCFGTAAGPHPFPTLVRDLQSVIGREARRQILEKTGRLPHMVVACVGGGSNAIGAFHA
FIPDGQVQLVGVEAAGSGEPGCYNSAPINLGTPGVLHGNHTMLLQSADGQILPSHSVAAGLDYPGVGPEHAALGRSGRAR
YGMVNDAQALHAFKTLSRMEGIIPALESSHAVAWVLENRDGIPRGADVVVNLSGRGDKDMGIINNLL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=55.46875, Blast_Score=425, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=54.9479166666667, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 41331; Mature: 41331

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGYFGDFGGQFVPELLMPPLKELENALETVVPSPEFQNEFHMLLREYVGRETPLTLCR
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
RLSAELGFNLWLKREDLAHSGSHKINNTLGQALLTKHMGKPAMLAETGAGQHGVATATAA
HHHHHCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH
AALGLECVVFMGAVDVERQALNVERMRLLGAEVVPVQSGTRTLKDAINEAMRFWIANIAT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
HHYCFGTAAGPHPFPTLVRDLQSVIGREARRQILEKTGRLPHMVVACVGGGSNAIGAFHA
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHEE
FIPDGQVQLVGVEAAGSGEPGCYNSAPINLGTPGVLHGNHTMLLQSADGQILPSHSVAAG
ECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCHHCC
LDYPGVGPEHAALGRSGRARYGMVNDAQALHAFKTLSRMEGIIPALESSHAVAWVLENRD
CCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
GIPRGADVVVNLSGRGDKDMGIINNLL
CCCCCCEEEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MKKGYFGDFGGQFVPELLMPPLKELENALETVVPSPEFQNEFHMLLREYVGRETPLTLCR
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
RLSAELGFNLWLKREDLAHSGSHKINNTLGQALLTKHMGKPAMLAETGAGQHGVATATAA
HHHHHCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH
AALGLECVVFMGAVDVERQALNVERMRLLGAEVVPVQSGTRTLKDAINEAMRFWIANIAT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
HHYCFGTAAGPHPFPTLVRDLQSVIGREARRQILEKTGRLPHMVVACVGGGSNAIGAFHA
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHEE
FIPDGQVQLVGVEAAGSGEPGCYNSAPINLGTPGVLHGNHTMLLQSADGQILPSHSVAAG
ECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCHHCC
LDYPGVGPEHAALGRSGRARYGMVNDAQALHAFKTLSRMEGIIPALESSHAVAWVLENRD
CCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
GIPRGADVVVNLSGRGDKDMGIINNLL
CCCCCCEEEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA