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The map label for this gene is hldD [H]

Identifier: 78358505

GI number: 78358505

Start: 3427108

End: 3428097

Strand: Reverse

Name: hldD [H]

Synonym: Dde_3466

Alternate gene names: 78358505

Gene position: 3428097-3427108 (Counterclockwise)

Preceding gene: 78358506

Following gene: 78358500

Centisome position: 91.9

GC content: 54.24

Gene sequence:

>990_bases
ATGTACATAGTCACAGGTGGCGCAGGATTTATCGGCAGCGCCATGGTCTGGAAGCTCAACACCATGGGCATAGACAATAT
TCTGGTGGTGGATAATCTGGCCAGTACGGAAAAATGGAAGAATCTCGTAAATCTGCGGTATGTCGATTACATGCACCGCG
ATGCATTTCTCGATCTGCTGCTGGATGACTGCCTGCCGTGGAACGTGAAGGGCATTGTGCATATGGGCGCCTGCTCTTCC
ACCACGGAACGCGACGCTGATTTTCTGATGGAGAACAACTATCGCTATACCAAAGCCCTGTGTGATTTTGCCCTGCAGCA
TGGCGCGCGTTTTATCAATGCCAGCTCGGCAGCCACCTACGGCGACGGCTCATGCGGGTTTGATGATTCCGTGGAAACCA
TGCACCGCATCAAGCCGCTGAACATGTACGGCTATTCCAAACAGCTGTTTGACCTGCGCGCCCATGCCGAAGGCAAGCTG
GACAGCATAGCCAGCCTGAAATTTTTCAATGTTTACGGTCCCAACGAATACCATAAGGACGATATGCGTTCGGTGGTGTG
TAAGGCTTTTTCACAGATAGGTTCCGAAGGGGTCATGCGTCTTTTCCGCTCGTATCACCCCGATTATCCCGACGGCGGGC
AGAAGCGTGATTTTGTATACGTGAAAGACTGCGTGGACGTGATGTGGTGGCTGCTGGAAAATCCTTCCGCCAACGGGCTG
TTCAATATCGGCACCGGCAACGCCCGTACGTGGAACGATCTGGCGCGGGCGGTGTTCAGCGCCATGGACGTGCCCGAACG
CATCGAATACATCGATATGCCCGAGCAGCTGCGCGGCAAATACCAGTATTACACGCAGGCTCCCGTGCAGCGGCTGGCTG
ATGCCGGTTGTCCGGTGACGTTCCGTTCGCTGGAAGACGGTGTTAAGGATTATGTGCAGAATTATCTTGCAGCGGAAGAT
CCGTATCTCGACCCCCGTGCAGGGGTATAG

Upstream 100 bases:

>100_bases
CCGCGGCGTAAAACGCCGCACTGCAGGCGGCATGGTGATGAACAGCGGCGGACAGGGGATGACCGGCCCGCCGCACTCAC
GGTTTTTTTCAGGAGAATAT

Downstream 100 bases:

>100_bases
GCGCATACCGGAAAGGGTGCGTAACGCTCAGAACGCCGGGGGCAGGTCCTGCGGCGTTTTTTTTATGCGGCGGCAGCACG
TCAGGAAGCACCGGCACCCG

Product: ADP-glyceromanno-heptose 6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MYIVTGGAGFIGSAMVWKLNTMGIDNILVVDNLASTEKWKNLVNLRYVDYMHRDAFLDLLLDDCLPWNVKGIVHMGACSS
TTERDADFLMENNYRYTKALCDFALQHGARFINASSAATYGDGSCGFDDSVETMHRIKPLNMYGYSKQLFDLRAHAEGKL
DSIASLKFFNVYGPNEYHKDDMRSVVCKAFSQIGSEGVMRLFRSYHPDYPDGGQKRDFVYVKDCVDVMWWLLENPSANGL
FNIGTGNARTWNDLARAVFSAMDVPERIEYIDMPEQLRGKYQYYTQAPVQRLADAGCPVTFRSLEDGVKDYVQNYLAAED
PYLDPRAGV

Sequences:

>Translated_329_residues
MYIVTGGAGFIGSAMVWKLNTMGIDNILVVDNLASTEKWKNLVNLRYVDYMHRDAFLDLLLDDCLPWNVKGIVHMGACSS
TTERDADFLMENNYRYTKALCDFALQHGARFINASSAATYGDGSCGFDDSVETMHRIKPLNMYGYSKQLFDLRAHAEGKL
DSIASLKFFNVYGPNEYHKDDMRSVVCKAFSQIGSEGVMRLFRSYHPDYPDGGQKRDFVYVKDCVDVMWWLLENPSANGL
FNIGTGNARTWNDLARAVFSAMDVPERIEYIDMPEQLRGKYQYYTQAPVQRLADAGCPVTFRSLEDGVKDYVQNYLAAED
PYLDPRAGV
>Mature_329_residues
MYIVTGGAGFIGSAMVWKLNTMGIDNILVVDNLASTEKWKNLVNLRYVDYMHRDAFLDLLLDDCLPWNVKGIVHMGACSS
TTERDADFLMENNYRYTKALCDFALQHGARFINASSAATYGDGSCGFDDSVETMHRIKPLNMYGYSKQLFDLRAHAEGKL
DSIASLKFFNVYGPNEYHKDDMRSVVCKAFSQIGSEGVMRLFRSYHPDYPDGGQKRDFVYVKDCVDVMWWLLENPSANGL
FNIGTGNARTWNDLARAVFSAMDVPERIEYIDMPEQLRGKYQYYTQAPVQRLADAGCPVTFRSLEDGVKDYVQNYLAAED
PYLDPRAGV

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=314, Percent_Identity=43.6305732484076, Blast_Score=231, Evalue=5e-62,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37264; Mature: 37264

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIVTGGAGFIGSAMVWKLNTMGIDNILVVDNLASTEKWKNLVNLRYVDYMHRDAFLDLL
CEEEECCCCHHCCHHEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDCLPWNVKGIVHMGACSSTTERDADFLMENNYRYTKALCDFALQHGARFINASSAATY
HHHCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCC
GDGSCGFDDSVETMHRIKPLNMYGYSKQLFDLRAHAEGKLDSIASLKFFNVYGPNEYHKD
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHEEEEEECCCCCCCHH
DMRSVVCKAFSQIGSEGVMRLFRSYHPDYPDGGQKRDFVYVKDCVDVMWWLLENPSANGL
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCE
FNIGTGNARTWNDLARAVFSAMDVPERIEYIDMPEQLRGKYQYYTQAPVQRLADAGCPVT
EEECCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCEE
FRSLEDGVKDYVQNYLAAEDPYLDPRAGV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MYIVTGGAGFIGSAMVWKLNTMGIDNILVVDNLASTEKWKNLVNLRYVDYMHRDAFLDLL
CEEEECCCCHHCCHHEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDCLPWNVKGIVHMGACSSTTERDADFLMENNYRYTKALCDFALQHGARFINASSAATY
HHHCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCC
GDGSCGFDDSVETMHRIKPLNMYGYSKQLFDLRAHAEGKLDSIASLKFFNVYGPNEYHKD
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHEEEEEECCCCCCCHH
DMRSVVCKAFSQIGSEGVMRLFRSYHPDYPDGGQKRDFVYVKDCVDVMWWLLENPSANGL
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCE
FNIGTGNARTWNDLARAVFSAMDVPERIEYIDMPEQLRGKYQYYTQAPVQRLADAGCPVT
EEECCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCEE
FRSLEDGVKDYVQNYLAAEDPYLDPRAGV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA