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The map label for this gene is mcp4 [H]

Identifier: 78358301

GI number: 78358301

Start: 3257558

End: 3259399

Strand: Reverse

Name: mcp4 [H]

Synonym: Dde_3261

Alternate gene names: 78358301

Gene position: 3259399-3257558 (Counterclockwise)

Preceding gene: 78358303

Following gene: 78358300

Centisome position: 87.38

GC content: 56.62

Gene sequence:

>1842_bases
GTGGTACCTGTTTTACCAAAGGAGTCTGCAGTGCTCAGAAAGTTTACTATTGCAAGCCGCATCATTTTTCTGCTGGTGTT
GATGCTGGTGTTCTCTACCATCGTCGGTGGCATTTATACGTATTTTCTCTACAAAGTGCAGGACAGGTCGCTTACGGAAA
CAGAAGCCGTGCTGCATGAAGGGTATGAGCGGAGCATGAAGTTTGCCGTGCAGACTCTGGCCACCAACCTTGCCCATGTG
GCGCAGACGGCGCGCAGCAGCGGGCAGGATCCCGTGGAAGCGATGCGTGCGGCCATAGCGCCGGTGCGTTTCGGCGGAGA
CGGGTATTATTTTATCTATAATACGCAGGGGTACACCGTGGCCCATCCGCTGCGGCCCGATTTTAACGGGCAGCCCGGTA
TGGATAAGAAAGACCAGAAAGGCAACCAGTACATCAGGCAGCTCAATGAAAAAGCCATGAGCGGCGGGGGCTTTGTCACC
TACTGGTTCAACAAGCCCAATGAGCGCGAGCCCAGCCCCAAACTGGCATACGCCCAGATGATCGAAGGCACTGATCTGTG
GCTTTCCACCGGTGTGTATGTGGATGATATTCAGGAGGAGCGGGAGCGCATACGGGCAACACTTGAGGCTCTGCTGGATG
AGGCCCGCAATATTGCGCTGACAGTTGTCGGTGTGCTCTTTTTGCTGCTGGTACTGCCTTTTGCCATAAGCATCGTGCGC
AGTATTCTGCTGCCGCTGCGCGCGGCCACAGGCAACGCACAGCAGGTAGCTGCGGGTAATCTTGATGTGGTCATTGCCGT
GGAGGGCAGGGACGAAATCACCCGTCTGGAAGAAGCGCTGCATACCATGCTGGCCACGCTGAACAACAACATTAAAGAAA
TTGAAGTGAAAAGCCGCCATGCCGAAGAGCAGGCCAGAGCGGCAGAACAGGCGGCAAAACAAGCGGATGAAGCCAGAAAG
GCTGCGGAAAATGCCAAAAGCGAAGGCATGCGCGCTGCTGCTGCCAGACTGGAAACCATTATGCACCATGTGACCTCGGC
GTCCGAGAGCATTTCCGGTCAGGCGGAGGAAATGCGTCAGGGGGCCGAACTGCAGGCCGAGCGCATAGCAGGCACTGCCA
CCGCCATGGAAGAGATGAATGCCACTGTGTTCGAGATTGCGCGCAACTCTGCGGAGGCGGCCGAAGCAGGCATGCAGGCC
GGTGAAAAAGCCAACGCGGGCGCCGACACCGTGCGTATGTCCATCAAATCCATGCTGCACACGCAGGAGCAGGCCGAACG
GCTTAAAACCAACATGGCGCATCTGGGTACACAGGCTGAATCCATCGGCATGATTATGACCGTTATTGAAGACATAGCCG
ACCAGACAAACCTGCTGGCGCTCAATGCCGCCATCGAGGCGGCGCGGGCCGGCGATGCCGGACGCGGTTTTGCCGTGGTG
GCCGACGAGGTGCGCAAACTTGCGGAAAAAACCATGGGGGCCACCAAACAGGTCGGCGATTCCATAGGGGCCATCCAGCA
GGTGGCGCGTGAAAATATCGATTCCGTGGAAGCTGCCGTGGCCAGCCTGAACGAAGCTGTGGGCCTTACGGAAGAATCCG
GCACGGCGCTTAAGGAAATCGTGGACAGCGTGGAGCGTACCGCAGGACAGATTCAGCAGATAGCCACGGCCGCGGAAGAA
CAGTCGGCCACCTCTGAAGAAATCAACAGAGCCATTGAGGAAATAAGCAACATCACCAGAGAGACATCCGAAGGTGTGAG
CAGCACGGTTTCTTCTCTCAGCGACCTTGCAGAACAGCTGGACACGTTGAACAGTCTTGTTCAGGAACTGAAAAGCAGCT
GA

Upstream 100 bases:

>100_bases
ACCGCAGGGCATGAGCGCGGCAACTGGATTATATCGTAAATAATGTTGCAGAAGTGAACTGTGGATTATATATCATAATA
AGCATAGGTTCTGTCTGTCC

Downstream 100 bases:

>100_bases
CCGGAGCAGCATCTTTTGCGGCATACGGAGAGGCCGGTCCATGAACGGATACACGGCTGCACCCGCCTGAAGCATACCGG
AACATAGCACCATCAGGGGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MVPVLPKESAVLRKFTIASRIIFLLVLMLVFSTIVGGIYTYFLYKVQDRSLTETEAVLHEGYERSMKFAVQTLATNLAHV
AQTARSSGQDPVEAMRAAIAPVRFGGDGYYFIYNTQGYTVAHPLRPDFNGQPGMDKKDQKGNQYIRQLNEKAMSGGGFVT
YWFNKPNEREPSPKLAYAQMIEGTDLWLSTGVYVDDIQEERERIRATLEALLDEARNIALTVVGVLFLLLVLPFAISIVR
SILLPLRAATGNAQQVAAGNLDVVIAVEGRDEITRLEEALHTMLATLNNNIKEIEVKSRHAEEQARAAEQAAKQADEARK
AAENAKSEGMRAAAARLETIMHHVTSASESISGQAEEMRQGAELQAERIAGTATAMEEMNATVFEIARNSAEAAEAGMQA
GEKANAGADTVRMSIKSMLHTQEQAERLKTNMAHLGTQAESIGMIMTVIEDIADQTNLLALNAAIEAARAGDAGRGFAVV
ADEVRKLAEKTMGATKQVGDSIGAIQQVARENIDSVEAAVASLNEAVGLTEESGTALKEIVDSVERTAGQIQQIATAAEE
QSATSEEINRAIEEISNITRETSEGVSSTVSSLSDLAEQLDTLNSLVQELKSS

Sequences:

>Translated_613_residues
MVPVLPKESAVLRKFTIASRIIFLLVLMLVFSTIVGGIYTYFLYKVQDRSLTETEAVLHEGYERSMKFAVQTLATNLAHV
AQTARSSGQDPVEAMRAAIAPVRFGGDGYYFIYNTQGYTVAHPLRPDFNGQPGMDKKDQKGNQYIRQLNEKAMSGGGFVT
YWFNKPNEREPSPKLAYAQMIEGTDLWLSTGVYVDDIQEERERIRATLEALLDEARNIALTVVGVLFLLLVLPFAISIVR
SILLPLRAATGNAQQVAAGNLDVVIAVEGRDEITRLEEALHTMLATLNNNIKEIEVKSRHAEEQARAAEQAAKQADEARK
AAENAKSEGMRAAAARLETIMHHVTSASESISGQAEEMRQGAELQAERIAGTATAMEEMNATVFEIARNSAEAAEAGMQA
GEKANAGADTVRMSIKSMLHTQEQAERLKTNMAHLGTQAESIGMIMTVIEDIADQTNLLALNAAIEAARAGDAGRGFAVV
ADEVRKLAEKTMGATKQVGDSIGAIQQVARENIDSVEAAVASLNEAVGLTEESGTALKEIVDSVERTAGQIQQIATAAEE
QSATSEEINRAIEEISNITRETSEGVSSTVSSLSDLAEQLDTLNSLVQELKSS
>Mature_613_residues
MVPVLPKESAVLRKFTIASRIIFLLVLMLVFSTIVGGIYTYFLYKVQDRSLTETEAVLHEGYERSMKFAVQTLATNLAHV
AQTARSSGQDPVEAMRAAIAPVRFGGDGYYFIYNTQGYTVAHPLRPDFNGQPGMDKKDQKGNQYIRQLNEKAMSGGGFVT
YWFNKPNEREPSPKLAYAQMIEGTDLWLSTGVYVDDIQEERERIRATLEALLDEARNIALTVVGVLFLLLVLPFAISIVR
SILLPLRAATGNAQQVAAGNLDVVIAVEGRDEITRLEEALHTMLATLNNNIKEIEVKSRHAEEQARAAEQAAKQADEARK
AAENAKSEGMRAAAARLETIMHHVTSASESISGQAEEMRQGAELQAERIAGTATAMEEMNATVFEIARNSAEAAEAGMQA
GEKANAGADTVRMSIKSMLHTQEQAERLKTNMAHLGTQAESIGMIMTVIEDIADQTNLLALNAAIEAARAGDAGRGFAVV
ADEVRKLAEKTMGATKQVGDSIGAIQQVARENIDSVEAAVASLNEAVGLTEESGTALKEIVDSVERTAGQIQQIATAAEE
QSATSEEINRAIEEISNITRETSEGVSSTVSSLSDLAEQLDTLNSLVQELKSS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=393, Percent_Identity=29.7709923664122, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI2367378, Length=362, Percent_Identity=29.5580110497238, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1787690, Length=412, Percent_Identity=29.3689320388349, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788195, Length=349, Percent_Identity=27.7936962750716, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789453, Length=252, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66321; Mature: 66321

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS00287 CYSTATIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVLPKESAVLRKFTIASRIIFLLVLMLVFSTIVGGIYTYFLYKVQDRSLTETEAVLHE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GYERSMKFAVQTLATNLAHVAQTARSSGQDPVEAMRAAIAPVRFGGDGYYFIYNTQGYTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEECCCEEEEEEECCCEEE
AHPLRPDFNGQPGMDKKDQKGNQYIRQLNEKAMSGGGFVTYWFNKPNEREPSPKLAYAQM
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHH
IEGTDLWLSTGVYVDDIQEERERIRATLEALLDEARNIALTVVGVLFLLLVLPFAISIVR
HCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILLPLRAATGNAQQVAAGNLDVVIAVEGRDEITRLEEALHTMLATLNNNIKEIEVKSRH
HHHHHHHHCCCCCHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHHH
AEEQARAAEQAAKQADEARKAAENAKSEGMRAAAARLETIMHHVTSASESISGQAEEMRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
GAELQAERIAGTATAMEEMNATVFEIARNSAEAAEAGMQAGEKANAGADTVRMSIKSMLH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
TQEQAERLKTNMAHLGTQAESIGMIMTVIEDIADQTNLLALNAAIEAARAGDAGRGFAVV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHH
ADEVRKLAEKTMGATKQVGDSIGAIQQVARENIDSVEAAVASLNEAVGLTEESGTALKEI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VDSVERTAGQIQQIATAAEEQSATSEEINRAIEEISNITRETSEGVSSTVSSLSDLAEQL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLNSLVQELKSS
HHHHHHHHHHHCC
>Mature Secondary Structure
MVPVLPKESAVLRKFTIASRIIFLLVLMLVFSTIVGGIYTYFLYKVQDRSLTETEAVLHE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GYERSMKFAVQTLATNLAHVAQTARSSGQDPVEAMRAAIAPVRFGGDGYYFIYNTQGYTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEECCCEEEEEEECCCEEE
AHPLRPDFNGQPGMDKKDQKGNQYIRQLNEKAMSGGGFVTYWFNKPNEREPSPKLAYAQM
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHH
IEGTDLWLSTGVYVDDIQEERERIRATLEALLDEARNIALTVVGVLFLLLVLPFAISIVR
HCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILLPLRAATGNAQQVAAGNLDVVIAVEGRDEITRLEEALHTMLATLNNNIKEIEVKSRH
HHHHHHHHCCCCCHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHHH
AEEQARAAEQAAKQADEARKAAENAKSEGMRAAAARLETIMHHVTSASESISGQAEEMRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
GAELQAERIAGTATAMEEMNATVFEIARNSAEAAEAGMQAGEKANAGADTVRMSIKSMLH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
TQEQAERLKTNMAHLGTQAESIGMIMTVIEDIADQTNLLALNAAIEAARAGDAGRGFAVV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHH
ADEVRKLAEKTMGATKQVGDSIGAIQQVARENIDSVEAAVASLNEAVGLTEESGTALKEI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VDSVERTAGQIQQIATAAEEQSATSEEINRAIEEISNITRETSEGVSSTVSSLSDLAEQL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLNSLVQELKSS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]