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The map label for this gene is atoS [H]

Identifier: 78358246

GI number: 78358246

Start: 3194950

End: 3196236

Strand: Reverse

Name: atoS [H]

Synonym: Dde_3206

Alternate gene names: 78358246

Gene position: 3196236-3194950 (Counterclockwise)

Preceding gene: 78358247

Following gene: 78358226

Centisome position: 85.68

GC content: 61.38

Gene sequence:

>1287_bases
ATGCCGCCGGCAGACGGCGGTCCGGCACTGCACATATCAGGGCCCGCGGCAACATTGCCGCGGGCCTTCTTTTGCCGCTT
GCGGTCTGTATTGTGCTGTGGCGCTGTGATATGCTGGTGTCACGGTCACAGACCGGGGTGCCGAAAAGGAAGGAGGATTC
CCGTGCTGCCTGCCAACCCGCTTTTTGTGGAGACCATTCTGACACGTATGCCCGTGGGCCTGATGATTCTGGACGGTGAC
GGAAACATAGCCCGCACCAATCCGGCGCTTTCCGCCATGCTGGGCATCGCACCGCATGAACTGCAGGGCCGCGGCTGGGC
GGAAGTGTTCATGGCGGAGGGCAATAATCTGGAATTCAATCAGGTCATAGTGGACGTGGTGCACAATGAACTGGAATTTC
TCAGCCGGTCTGTGCCGTTTGTCGATCCGGCGGGCAGTCGCCGCGAGCTTGGAGTGCTTTCCTGTTTCATCAGACAACAG
GATAGTGTTGCCGGTATTGTCCTGCTTTTTCAGGATATGACCGAACTTGCGCGCATGCATGATGCCGAGCGGCGTATTTA
TCGGGAAAAGCTGCGGCTGGAGCGCGAGCGCGAGGAAGCCCTGCGCCTGCTGGCTCAGGCTGTGGCGCATCAGGTGCGCA
ATCCGGCCACGGTCATAGGGGGCGTTGCGGGTATGCTCATCCGTCAGCATTCCGGCGAGCCTGCACTGGGCAGAATGCTG
GATGTCATCCGGGAAGAAACTCTGCGGCTGGAAGCCATGGTGGCGGAAGTTTCCTCTTTTGCGGCAATCTCCGCCGGAGT
GTTGCACCACGTCGACTGGCATGCCCTGCTGCATGGCTGGGCGGCGGACAGGCTGGCAGAAGCGGATGAGGCGGACATTG
TGCTGCATGCCTGTACAGGCATGGGCGTTGTGTATCCCGATCTTGTGCGCCTGCTGCTGGACGAGCTGTATGACAACGCC
CGCCGGTTTGCGCACACGGACAGGGCGCTCAAGGTGACGGTGTCCGTAAGCCACGAAGACGGATGGACGCGGCTGGTCAT
GCAGGACAACGGCAGGGGTATGGGGCGGGACTCGCTGCCGTATGTGTTTGATCCGTTTTTCACCTCGCGCAGCGACGGAG
TGGGAATGGGCCTGTGCAAGGTTAAACGCTGCATGATGCTGCACGGCGGAACTGCCGCGGCGGAAAATGTTCACGGCGGC
GGGGCGCGGTTCATCATGCGCTTTCCTCCGCGCAGCGCTTCGGCGGAAAACGGCGATGTGCCGCCGCCCGAAAACGGGCT
GCGCTGA

Upstream 100 bases:

>100_bases
TGAAACCAGTGAATTCGGCGATACTTCCACGCTTTCGGATCCCGGTGTCATCACCGACCTCATCGACGGACGTCTTGAAC
TGACGGGACGCTGATGTGGT

Downstream 100 bases:

>100_bases
CGGCCTTTCCCGCACGGGCTTTATGCTCCGGCGGATGGCGCACCGCGGGCTGATGCGCGTTACTGCCGGAGCAGCTTTTC
TGCCCGGCTGGCGTTTGTTT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MPPADGGPALHISGPAATLPRAFFCRLRSVLCCGAVICWCHGHRPGCRKGRRIPVLPANPLFVETILTRMPVGLMILDGD
GNIARTNPALSAMLGIAPHELQGRGWAEVFMAEGNNLEFNQVIVDVVHNELEFLSRSVPFVDPAGSRRELGVLSCFIRQQ
DSVAGIVLLFQDMTELARMHDAERRIYREKLRLEREREEALRLLAQAVAHQVRNPATVIGGVAGMLIRQHSGEPALGRML
DVIREETLRLEAMVAEVSSFAAISAGVLHHVDWHALLHGWAADRLAEADEADIVLHACTGMGVVYPDLVRLLLDELYDNA
RRFAHTDRALKVTVSVSHEDGWTRLVMQDNGRGMGRDSLPYVFDPFFTSRSDGVGMGLCKVKRCMMLHGGTAAAENVHGG
GARFIMRFPPRSASAENGDVPPPENGLR

Sequences:

>Translated_428_residues
MPPADGGPALHISGPAATLPRAFFCRLRSVLCCGAVICWCHGHRPGCRKGRRIPVLPANPLFVETILTRMPVGLMILDGD
GNIARTNPALSAMLGIAPHELQGRGWAEVFMAEGNNLEFNQVIVDVVHNELEFLSRSVPFVDPAGSRRELGVLSCFIRQQ
DSVAGIVLLFQDMTELARMHDAERRIYREKLRLEREREEALRLLAQAVAHQVRNPATVIGGVAGMLIRQHSGEPALGRML
DVIREETLRLEAMVAEVSSFAAISAGVLHHVDWHALLHGWAADRLAEADEADIVLHACTGMGVVYPDLVRLLLDELYDNA
RRFAHTDRALKVTVSVSHEDGWTRLVMQDNGRGMGRDSLPYVFDPFFTSRSDGVGMGLCKVKRCMMLHGGTAAAENVHGG
GARFIMRFPPRSASAENGDVPPPENGLR
>Mature_427_residues
PPADGGPALHISGPAATLPRAFFCRLRSVLCCGAVICWCHGHRPGCRKGRRIPVLPANPLFVETILTRMPVGLMILDGDG
NIARTNPALSAMLGIAPHELQGRGWAEVFMAEGNNLEFNQVIVDVVHNELEFLSRSVPFVDPAGSRRELGVLSCFIRQQD
SVAGIVLLFQDMTELARMHDAERRIYREKLRLEREREEALRLLAQAVAHQVRNPATVIGGVAGMLIRQHSGEPALGRMLD
VIREETLRLEAMVAEVSSFAAISAGVLHHVDWHALLHGWAADRLAEADEADIVLHACTGMGVVYPDLVRLLLDELYDNAR
RFAHTDRALKVTVSVSHEDGWTRLVMQDNGRGMGRDSLPYVFDPFFTSRSDGVGMGLCKVKRCMMLHGGTAAAENVHGGG
ARFIMRFPPRSASAENGDVPPPENGLR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=348, Percent_Identity=25, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=27.9475982532751, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=25.4310344827586, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46942; Mature: 46811

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPADGGPALHISGPAATLPRAFFCRLRSVLCCGAVICWCHGHRPGCRKGRRIPVLPANP
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCH
LFVETILTRMPVGLMILDGDGNIARTNPALSAMLGIAPHELQGRGWAEVFMAEGNNLEFN
HHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHCCCCHHCCCCCCEEEEEECCCCCCHH
QVIVDVVHNELEFLSRSVPFVDPAGSRRELGVLSCFIRQQDSVAGIVLLFQDMTELARMH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
DAERRIYREKLRLEREREEALRLLAQAVAHQVRNPATVIGGVAGMLIRQHSGEPALGRML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHH
DVIREETLRLEAMVAEVSSFAAISAGVLHHVDWHALLHGWAADRLAEADEADIVLHACTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
MGVVYPDLVRLLLDELYDNARRFAHTDRALKVTVSVSHEDGWTRLVMQDNGRGMGRDSLP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCCCCC
YVFDPFFTSRSDGVGMGLCKVKRCMMLHGGTAAAENVHGGGARFIMRFPPRSASAENGDV
CEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCC
PPPENGLR
CCCCCCCC
>Mature Secondary Structure 
PPADGGPALHISGPAATLPRAFFCRLRSVLCCGAVICWCHGHRPGCRKGRRIPVLPANP
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCH
LFVETILTRMPVGLMILDGDGNIARTNPALSAMLGIAPHELQGRGWAEVFMAEGNNLEFN
HHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHCCCCHHCCCCCCEEEEEECCCCCCHH
QVIVDVVHNELEFLSRSVPFVDPAGSRRELGVLSCFIRQQDSVAGIVLLFQDMTELARMH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
DAERRIYREKLRLEREREEALRLLAQAVAHQVRNPATVIGGVAGMLIRQHSGEPALGRML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHH
DVIREETLRLEAMVAEVSSFAAISAGVLHHVDWHALLHGWAADRLAEADEADIVLHACTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
MGVVYPDLVRLLLDELYDNARRFAHTDRALKVTVSVSHEDGWTRLVMQDNGRGMGRDSLP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCCCCC
YVFDPFFTSRSDGVGMGLCKVKRCMMLHGGTAAAENVHGGGARFIMRFPPRSASAENGDV
CEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCC
PPPENGLR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]