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The map label for this gene is fabG [H]

Identifier: 78357700

GI number: 78357700

Start: 2671885

End: 2672640

Strand: Direct

Name: fabG [H]

Synonym: Dde_2658

Alternate gene names: 78357700

Gene position: 2671885-2672640 (Clockwise)

Preceding gene: 78357699

Following gene: 78357701

Centisome position: 71.63

GC content: 66.01

Gene sequence:

>756_bases
ATGCGCCTGAGCCATACCCGCGGATGTGTACTGGTGGCGGGCGGCGGCAGCGCGTTGGGCACCGCTTCGGCCACGCTGCT
GGCCCGCGCGGGCGTACCGCTGTGCCTGACGGCAGGCAGCGCAGAGGCAGCCGCCCGCATACACAACGCTTTCAGCGCAG
CGCACCTATCCTGCCCGCCTGTACTCATCGTGCGCATGGAAGACACAACCCGCGCCGATGCCCTGCCGGAACAGGCGGCA
GCAGCCGCAGGCATGCCCGCGGCATATCTGCTGGACCTGATGCATACGGATCATGAAAGCCTGCTGGCATCGGCATCACC
GGACACAATCAGCGCATACATAGAAGCCAATATAACATGGCGTGCCCGTCTGGTGCGTGCGGTCAGCCGCCATATGCTGC
ACCGCCGCTGCGGCCGCATGGTTTTTGTCTCGTCAACGGCTGCGGCGCTGCCCGCCGCCGGACAGGGACTGTATGCCGCG
GCAAAACTGGCTGCCGAAGCCCTGTACCGCAGCACCGGTACAGAACTGGCCGCACGGGGCATCACAACATGCTCGCTGCG
TCTCGGATATGTGGCTGCAGGGCGCGGAGCCCGCTATCTGAAGCAGCATCCGGACCTGCTGCAGCGCATTCCGCTGCAAC
GGGCGGTGGACGTGCACGAGGCTGCCGGAGCACTGGCGTTCCTTCTCAGCGACGGAGCCGCCGCCATCAACGCCACCGCC
ATCACCATGGACGGCGGTCTGACCGCCTGCAAATAA

Upstream 100 bases:

>100_bases
CTCACGTCTGCACGGTCAGCGCAGTCACGGACGGCAGCGGCAGCGCATACCGGTGCACCCTGCTTGTGGACGGCGTCGCC
GCCGTCACAGGAACCATACA

Downstream 100 bases:

>100_bases
AAGGAGACCACAGCATGACTCAGCAGACCGCCCCCTGCGCCGTGACAGAACGGGTCATCGGCATCATCGCGGAAGTTCTC
GATATTCCGCCGCACACCAT

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MRLSHTRGCVLVAGGGSALGTASATLLARAGVPLCLTAGSAEAAARIHNAFSAAHLSCPPVLIVRMEDTTRADALPEQAA
AAAGMPAAYLLDLMHTDHESLLASASPDTISAYIEANITWRARLVRAVSRHMLHRRCGRMVFVSSTAAALPAAGQGLYAA
AKLAAEALYRSTGTELAARGITTCSLRLGYVAAGRGARYLKQHPDLLQRIPLQRAVDVHEAAGALAFLLSDGAAAINATA
ITMDGGLTACK

Sequences:

>Translated_251_residues
MRLSHTRGCVLVAGGGSALGTASATLLARAGVPLCLTAGSAEAAARIHNAFSAAHLSCPPVLIVRMEDTTRADALPEQAA
AAAGMPAAYLLDLMHTDHESLLASASPDTISAYIEANITWRARLVRAVSRHMLHRRCGRMVFVSSTAAALPAAGQGLYAA
AKLAAEALYRSTGTELAARGITTCSLRLGYVAAGRGARYLKQHPDLLQRIPLQRAVDVHEAAGALAFLLSDGAAAINATA
ITMDGGLTACK
>Mature_251_residues
MRLSHTRGCVLVAGGGSALGTASATLLARAGVPLCLTAGSAEAAARIHNAFSAAHLSCPPVLIVRMEDTTRADALPEQAA
AAAGMPAAYLLDLMHTDHESLLASASPDTISAYIEANITWRARLVRAVSRHMLHRRCGRMVFVSSTAAALPAAGQGLYAA
AKLAAEALYRSTGTELAARGITTCSLRLGYVAAGRGARYLKQHPDLLQRIPLQRAVDVHEAAGALAFLLSDGAAAINATA
ITMDGGLTACK

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=29.2887029288703, Blast_Score=78, Evalue=4e-16,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=28.2945736434109, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25893; Mature: 25893

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSHTRGCVLVAGGGSALGTASATLLARAGVPLCLTAGSAEAAARIHNAFSAAHLSCPP
CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCC
VLIVRMEDTTRADALPEQAAAAAGMPAAYLLDLMHTDHESLLASASPDTISAYIEANITW
EEEEEECCCCCHHCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCEEEEEEEECCHH
RARLVRAVSRHMLHRRCGRMVFVSSTAAALPAAGQGLYAAAKLAAEALYRSTGTELAARG
HHHHHHHHHHHHHHHHHCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
ITTCSLRLGYVAAGRGARYLKQHPDLLQRIPLQRAVDVHEAAGALAFLLSDGAAAINATA
CEEEEEEECEEECCCCCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ITMDGGLTACK
EEECCCCCCCC
>Mature Secondary Structure
MRLSHTRGCVLVAGGGSALGTASATLLARAGVPLCLTAGSAEAAARIHNAFSAAHLSCPP
CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCC
VLIVRMEDTTRADALPEQAAAAAGMPAAYLLDLMHTDHESLLASASPDTISAYIEANITW
EEEEEECCCCCHHCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCEEEEEEEECCHH
RARLVRAVSRHMLHRRCGRMVFVSSTAAALPAAGQGLYAAAKLAAEALYRSTGTELAARG
HHHHHHHHHHHHHHHHHCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
ITTCSLRLGYVAAGRGARYLKQHPDLLQRIPLQRAVDVHEAAGALAFLLSDGAAAINATA
CEEEEEEECEEECCCCCHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ITMDGGLTACK
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10464226; 10984043 [H]