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The map label for this gene is dcrA [H]

Identifier: 78357627

GI number: 78357627

Start: 2601000

End: 2602658

Strand: Direct

Name: dcrA [H]

Synonym: Dde_2585

Alternate gene names: 78357627

Gene position: 2601000-2602658 (Clockwise)

Preceding gene: 78357626

Following gene: 78357628

Centisome position: 69.73

GC content: 51.12

Gene sequence:

>1659_bases
GTGACAAAAAGCATACAGACTATACTCATCCTGATACTTGTAGCCGTTGTAACAACTATCCTTACGGCTTTCGGTGCTCA
GAGCTACTATCTGGAGCAGACCAAGCAGCTCGCCCTGCTGACTAATGAAAGTAACCGTGCAGCGGCACGCCTTGCGGTCA
ACATGGCGTCCCCCATGTGGGAACTGGATGAAGATCTGGCAAGCGATGTGGTGGCTTCCGAAATGCAGGCAGAGAACGTC
CACACGGTGGTCATATGGGAACCTGATCAGGAAAAAATCTTTTACGGCCGCACCAAAGCAGGAACTGAAGAAGCCGAAGC
AGACCAGCTGCCTGAAGGTTCTGACTATATCACAGCAACAAGCGAAGTATTGCACAAAGAATCTGTCATAGGCGTCGCCG
GTGTAGCTGTCAGCAAAGCAAACATGCGCGCTGACCTTCGCGCCACCCTGCAAAAAATAGCGTTAACCACCATCACTATA
GATGCTCTGCTTATTTTCGCACTCTTCATGGCCATGCGGTCAGTTATCATAAAGCCCCTTAAATCCATCGAAGAATACGT
TGTGAGCATCAGTAACGGAAACTATGATGTGGGTTTCAGTGCCGCACGCTTTCTCGGCGAACTCAAGCGGCTGCGTACAG
CAGTTGAAACCATGGTAGAGAACCTGAAGCGCAATATATCTGAAATACAGATAAAAGAGAAAGAAGCAGCAAAAGCTGCA
GCGGAAGCAAAACAGGCATTCGCCGCTGCTGAAGAATCCAAAGAAAAAGCTGTAAGAGCGCGTCGCGAAGGTCTGCTGGA
AGCTGCAGGTGTTCTGAAAGGCATCGGCGGCCGCATAAGAGAAGCTTCGTCTGACCTTTCTGAAAAAGTGGATGCTGTGA
CGTCACGCAGCGACCAGCAGCGAGAACGGGCCACATCTACGGCCACCGCCATGGAAGAAATGAACGCAACGGTTCTGGAA
GTGGCCAGAAGTGCATCGGAAGCCGCACTCAGCGCTGAAGAATCACGTTCAACTGCGGGGCTCGGTTCCTCAAAAGTTGT
GGAACTGGTAACGACCATTAAAGACGTGGTACAGCAGACGGAAAACCTGAAAAACAGCCTGAATGTCCTTGGCAGCCATG
CCGAAGGCATCGGGCGTATCATGGGCGTAATTAACGATATTGCCGACCAGACTAACCTGCTGGCGCTCAATGCGGCTATC
GAAGCCGCACGGGCTGGTGACGCCGGCAGAGGTTTTGCCGTGGTGGCGGATGAAGTCCGCAAGCTGGCAGAAAAAACCAT
GCAGGCAACCAAAGAAGTTGAAACCGTTGTCCGTGATATACAAAGCAGCAGCCAGATAAACATATCCGGCATGGAGCAGA
CTTCTGAAGTGGTACGCACAAGTACAACCCTGGCAGAAGAAGCCGGGCGGTCTCTGGAGCAGATAGTCCGCACCATAGAA
ATGACATCAGATCAGGTGCGCAGCATCGCCACTGCAAGCGAAGAACAATCCGCGAGCAGTGAGGAAATTAACCAAGCCAT
GGTCCACATCAATGACTTGGCAGCAGAAATTGCAGACGATATGGCACTGGCCAATGATGCCATCAATGAGTTGTCGACCT
ATGCAAACAATCTTGCCGAGTTGATAGAAAAACTGGAACACGACGGAGAAGATAACTGA

Upstream 100 bases:

>100_bases
AAATTGAAGCTATTGTTGCCGGATATAAATAACTGAACAAAGCAGGAAGCCTTCGCACGGAGGCTTCCTGCTCCGGCCCC
GAAACAGCTCGGAGGGCATT

Downstream 100 bases:

>100_bases
CCCATACGGTTCCGAATACCCTGCGTCCAAAGCTCCCGATACCACGCAGGAGTACTGAAACCCGGTCCCCTTCTTTCACC
CTTGGTCTTCTTAGTCGGCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MTKSIQTILILILVAVVTTILTAFGAQSYYLEQTKQLALLTNESNRAAARLAVNMASPMWELDEDLASDVVASEMQAENV
HTVVIWEPDQEKIFYGRTKAGTEEAEADQLPEGSDYITATSEVLHKESVIGVAGVAVSKANMRADLRATLQKIALTTITI
DALLIFALFMAMRSVIIKPLKSIEEYVVSISNGNYDVGFSAARFLGELKRLRTAVETMVENLKRNISEIQIKEKEAAKAA
AEAKQAFAAAEESKEKAVRARREGLLEAAGVLKGIGGRIREASSDLSEKVDAVTSRSDQQRERATSTATAMEEMNATVLE
VARSASEAALSAEESRSTAGLGSSKVVELVTTIKDVVQQTENLKNSLNVLGSHAEGIGRIMGVINDIADQTNLLALNAAI
EAARAGDAGRGFAVVADEVRKLAEKTMQATKEVETVVRDIQSSSQINISGMEQTSEVVRTSTTLAEEAGRSLEQIVRTIE
MTSDQVRSIATASEEQSASSEEINQAMVHINDLAAEIADDMALANDAINELSTYANNLAELIEKLEHDGEDN

Sequences:

>Translated_552_residues
MTKSIQTILILILVAVVTTILTAFGAQSYYLEQTKQLALLTNESNRAAARLAVNMASPMWELDEDLASDVVASEMQAENV
HTVVIWEPDQEKIFYGRTKAGTEEAEADQLPEGSDYITATSEVLHKESVIGVAGVAVSKANMRADLRATLQKIALTTITI
DALLIFALFMAMRSVIIKPLKSIEEYVVSISNGNYDVGFSAARFLGELKRLRTAVETMVENLKRNISEIQIKEKEAAKAA
AEAKQAFAAAEESKEKAVRARREGLLEAAGVLKGIGGRIREASSDLSEKVDAVTSRSDQQRERATSTATAMEEMNATVLE
VARSASEAALSAEESRSTAGLGSSKVVELVTTIKDVVQQTENLKNSLNVLGSHAEGIGRIMGVINDIADQTNLLALNAAI
EAARAGDAGRGFAVVADEVRKLAEKTMQATKEVETVVRDIQSSSQINISGMEQTSEVVRTSTTLAEEAGRSLEQIVRTIE
MTSDQVRSIATASEEQSASSEEINQAMVHINDLAAEIADDMALANDAINELSTYANNLAELIEKLEHDGEDN
>Mature_551_residues
TKSIQTILILILVAVVTTILTAFGAQSYYLEQTKQLALLTNESNRAAARLAVNMASPMWELDEDLASDVVASEMQAENVH
TVVIWEPDQEKIFYGRTKAGTEEAEADQLPEGSDYITATSEVLHKESVIGVAGVAVSKANMRADLRATLQKIALTTITID
ALLIFALFMAMRSVIIKPLKSIEEYVVSISNGNYDVGFSAARFLGELKRLRTAVETMVENLKRNISEIQIKEKEAAKAAA
EAKQAFAAAEESKEKAVRARREGLLEAAGVLKGIGGRIREASSDLSEKVDAVTSRSDQQRERATSTATAMEEMNATVLEV
ARSASEAALSAEESRSTAGLGSSKVVELVTTIKDVVQQTENLKNSLNVLGSHAEGIGRIMGVINDIADQTNLLALNAAIE
AARAGDAGRGFAVVADEVRKLAEKTMQATKEVETVVRDIQSSSQINISGMEQTSEVVRTSTTLAEEAGRSLEQIVRTIEM
TSDQVRSIATASEEQSASSEEINQAMVHINDLAAEIADDMALANDAINELSTYANNLAELIEKLEHDGEDN

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=250, Percent_Identity=34.8, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788194, Length=387, Percent_Identity=27.6485788113695, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788195, Length=211, Percent_Identity=36.4928909952607, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787690, Length=379, Percent_Identity=27.9683377308707, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=28.3261802575107, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 59468; Mature: 59336

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSIQTILILILVAVVTTILTAFGAQSYYLEQTKQLALLTNESNRAAARLAVNMASPMW
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCHH
ELDEDLASDVVASEMQAENVHTVVIWEPDQEKIFYGRTKAGTEEAEADQLPEGSDYITAT
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCHHHHHCCCCCCCCCHHH
SEVLHKESVIGVAGVAVSKANMRADLRATLQKIALTTITIDALLIFALFMAMRSVIIKPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIEEYVVSISNGNYDVGFSAARFLGELKRLRTAVETMVENLKRNISEIQIKEKEAAKAA
HHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKQAFAAAEESKEKAVRARREGLLEAAGVLKGIGGRIREASSDLSEKVDAVTSRSDQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHH
RERATSTATAMEEMNATVLEVARSASEAALSAEESRSTAGLGSSKVVELVTTIKDVVQQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ENLKNSLNVLGSHAEGIGRIMGVINDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCHHHHHHHHH
KLAEKTMQATKEVETVVRDIQSSSQINISGMEQTSEVVRTSTTLAEEAGRSLEQIVRTIE
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSDQVRSIATASEEQSASSEEINQAMVHINDLAAEIADDMALANDAINELSTYANNLAE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEKLEHDGEDN
HHHHHHCCCCCC
>Mature Secondary Structure 
TKSIQTILILILVAVVTTILTAFGAQSYYLEQTKQLALLTNESNRAAARLAVNMASPMW
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCHH
ELDEDLASDVVASEMQAENVHTVVIWEPDQEKIFYGRTKAGTEEAEADQLPEGSDYITAT
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCHHHHHCCCCCCCCCHHH
SEVLHKESVIGVAGVAVSKANMRADLRATLQKIALTTITIDALLIFALFMAMRSVIIKPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIEEYVVSISNGNYDVGFSAARFLGELKRLRTAVETMVENLKRNISEIQIKEKEAAKAA
HHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKQAFAAAEESKEKAVRARREGLLEAAGVLKGIGGRIREASSDLSEKVDAVTSRSDQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHH
RERATSTATAMEEMNATVLEVARSASEAALSAEESRSTAGLGSSKVVELVTTIKDVVQQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ENLKNSLNVLGSHAEGIGRIMGVINDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCHHHHHHHHH
KLAEKTMQATKEVETVVRDIQSSSQINISGMEQTSEVVRTSTTLAEEAGRSLEQIVRTIE
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSDQVRSIATASEEQSASSEEINQAMVHINDLAAEIADDMALANDAINELSTYANNLAE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEKLEHDGEDN
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]