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The map label for this gene is ybaL [H]

Identifier: 78355774

GI number: 78355774

Start: 747495

End: 749507

Strand: Direct

Name: ybaL [H]

Synonym: Dde_0727

Alternate gene names: 78355774

Gene position: 747495-749507 (Clockwise)

Preceding gene: 78355773

Following gene: 78355790

Centisome position: 20.04

GC content: 61.35

Gene sequence:

>2013_bases
ATGGAGTTACTAGGTAATCTTGTTCTTGTGCTTGCTTTTTCCGTGGGCGTGGTGCTGCTGGCCCAGAAATTCCGCATTCC
CGCCATGGTGGGATTTCTGCTGGCGGGTGTGGCTGCCGGACCTCATGCACTGGGTATGGTTTCCGACGTGGCCGCAGTGG
ACGTGCTGGCTGAAATAGGTGTTGTACTGCTGCTGTTTACACTGGGTATGGAATTTTCCATAGCCCGTCTGCGCGCATTG
TTCCGCGTGGCGCTGCTGGGCGGCGGCACACAGGTGGCCGTCACCGCGCTGGCGGCCGGCAGTGTGGCACACTGGCTGCT
GGGCATTGCATGGAACACCTCTGTTTTTATAGGTTTTCTCATTGCTCTTTCCAGTACGGCCATAGGTATCCGGCTGATGC
GTGACAAAGGCGACGTGGAAACACCCCACGGTACGGCCGCGCTGGGCATACTTATTTTTCAGGATATGGCCGTGGTGCCC
ATGATGCTGCTTGTACCGGTGCTTGCCGGGCAGGAGGGCAGCGTGGCGTGGGCGCTGGTCACGCTGACGGCCAAAACCGC
TCTGGTGGTGGCCGGCGTGCTGTTTCTTGCCGTGCGCGGGGTGCCGCACCTGCTGCATTATGTGGCCCGCTGGCGTAACC
GCGAGCTGTTTCTGCTCACGCTTCTTTCCATCTGCTTCGGGGTGGCGTGGGGCACCCATGCCGCCGGACTTTCGCTCGCG
CTGGGCGCTTTTCTGGCGGGGCTGGTCATTTCCGGTTCGGAATACGAACACTACGCGGCTTCTCAGGTGCTGCCGCTGCA
TGATCTTTTCATATGCTTCTTTTTCGTTTCGGTGGGTATGAGTCTGGATGTGGGGCTGGCACTGACAAATCCGCTCATCG
TGCTGACGCTCACAGCGTTGCTCATGCTGTCCAAGTTTGTGCTTGTGACCGGCTCTGCCCTGCTGCCGGGTCTGGGGTTT
GCCAGCGCGGTCATGACAGGCGGCATGCTGTGTCAGGTGGGTGAATTTTCCTTCATCCTTGCCCGGCTGGGTAACGAAGC
CGGACTTTTTTCCGGCGAGGCCATGCAGCTGTTTCTGGCCTCTGCGGTGGTCACCATGTTTCTTACACCGTGGGCCGCGG
GGTATGCGGGCCGTCTGGGACGTTTTCTGCGGCGCAGAGGCTCCTCGGCGCTGCGCGACCATACCGGCGTGACCAGCACG
GCGCAAAGCGACCATCTGGTCATTATCGGATACGGTCCCGGCGGCAGACATCTGGCGCAGGCGGCCCGTCTGTGGAACAT
CGATTACGTGGTCATAGACAGCAATCCCGACACGGTGCGTGATGAACGGGCGCGGGGTGTTCCCATCATGTTCGGCGATG
CGGCCAGCGAAACCATGCTGGAACATGCGGGCGTGGAGCGGGCGCGCGCGGTTGCGGTGGTGGTTTCCGACCCTGTGGCG
GCCCGGACAGTGACGGCGCTGGTGCGCGAATTGTCGCCCGATGTGCAGATAATCACCCGTGCGCGGTATCTTGGCGAATA
TGACGGCATGCGCGAGGCAGGCGCCAATGATGTGGTGCCGGCCGAGATGGAGGCCTCGGTGGCCATGGTGGGACGTGTTC
TGGAACGCTTTATGGTGGGCAGCGATGAACTGAAGGCGTTTCTTGAGCGCATCCGTGCCGAAGGCTACCAGATGGATGCC
GAAGAGCTGGAAAAGCGCGGGAAGTATTCCTTCCTGCCCTTTATGCAGCTGCGGCAGGTACATGTGGAAGAGGGTTCCGC
CGTGCAGGGCAAGACACTGGGTGAACTGCACATCCGCCGCAAGTACCGTGTGGCGGTGATGGCCGTGCGGCATAACGGCA
CAGTGCTGCCTGTGCCGGGGGCCAAGACGGAACTGCTGCCCGGTGATGAGGTTCTGCTTTCGGGCTGCCCCGGCGATATC
GGCATTGTGGCGTCCATGTTCAGCAAGGGCGGTGCGCCCCTGCCGGACGAAAACGATACAATACCCGCCGGAACGGCCTG
CCCCGTGGAATAG

Upstream 100 bases:

>100_bases
ATTTGTAGCATTTTGGAATGGCTGAAAAAAAACTGCTTCGGCACTATGGCCCGGTTTCGATTTGCGCTATGCTGATGGCC
GATCATCCGGAGGACATCGT

Downstream 100 bases:

>100_bases
CGGGAACGCGCGGCTGCGTTGCTTACTTTTAAAACGCATGAACCGGCACCTCTGACGGGGTGCCGGTGTTTTTTTCCGCA
GCGGGCACAGCAGGTGCACG

Product: glutathione-regulated potassium-efflux system protein KefB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MELLGNLVLVLAFSVGVVLLAQKFRIPAMVGFLLAGVAAGPHALGMVSDVAAVDVLAEIGVVLLLFTLGMEFSIARLRAL
FRVALLGGGTQVAVTALAAGSVAHWLLGIAWNTSVFIGFLIALSSTAIGIRLMRDKGDVETPHGTAALGILIFQDMAVVP
MMLLVPVLAGQEGSVAWALVTLTAKTALVVAGVLFLAVRGVPHLLHYVARWRNRELFLLTLLSICFGVAWGTHAAGLSLA
LGAFLAGLVISGSEYEHYAASQVLPLHDLFICFFFVSVGMSLDVGLALTNPLIVLTLTALLMLSKFVLVTGSALLPGLGF
ASAVMTGGMLCQVGEFSFILARLGNEAGLFSGEAMQLFLASAVVTMFLTPWAAGYAGRLGRFLRRRGSSALRDHTGVTST
AQSDHLVIIGYGPGGRHLAQAARLWNIDYVVIDSNPDTVRDERARGVPIMFGDAASETMLEHAGVERARAVAVVVSDPVA
ARTVTALVRELSPDVQIITRARYLGEYDGMREAGANDVVPAEMEASVAMVGRVLERFMVGSDELKAFLERIRAEGYQMDA
EELEKRGKYSFLPFMQLRQVHVEEGSAVQGKTLGELHIRRKYRVAVMAVRHNGTVLPVPGAKTELLPGDEVLLSGCPGDI
GIVASMFSKGGAPLPDENDTIPAGTACPVE

Sequences:

>Translated_670_residues
MELLGNLVLVLAFSVGVVLLAQKFRIPAMVGFLLAGVAAGPHALGMVSDVAAVDVLAEIGVVLLLFTLGMEFSIARLRAL
FRVALLGGGTQVAVTALAAGSVAHWLLGIAWNTSVFIGFLIALSSTAIGIRLMRDKGDVETPHGTAALGILIFQDMAVVP
MMLLVPVLAGQEGSVAWALVTLTAKTALVVAGVLFLAVRGVPHLLHYVARWRNRELFLLTLLSICFGVAWGTHAAGLSLA
LGAFLAGLVISGSEYEHYAASQVLPLHDLFICFFFVSVGMSLDVGLALTNPLIVLTLTALLMLSKFVLVTGSALLPGLGF
ASAVMTGGMLCQVGEFSFILARLGNEAGLFSGEAMQLFLASAVVTMFLTPWAAGYAGRLGRFLRRRGSSALRDHTGVTST
AQSDHLVIIGYGPGGRHLAQAARLWNIDYVVIDSNPDTVRDERARGVPIMFGDAASETMLEHAGVERARAVAVVVSDPVA
ARTVTALVRELSPDVQIITRARYLGEYDGMREAGANDVVPAEMEASVAMVGRVLERFMVGSDELKAFLERIRAEGYQMDA
EELEKRGKYSFLPFMQLRQVHVEEGSAVQGKTLGELHIRRKYRVAVMAVRHNGTVLPVPGAKTELLPGDEVLLSGCPGDI
GIVASMFSKGGAPLPDENDTIPAGTACPVE
>Mature_670_residues
MELLGNLVLVLAFSVGVVLLAQKFRIPAMVGFLLAGVAAGPHALGMVSDVAAVDVLAEIGVVLLLFTLGMEFSIARLRAL
FRVALLGGGTQVAVTALAAGSVAHWLLGIAWNTSVFIGFLIALSSTAIGIRLMRDKGDVETPHGTAALGILIFQDMAVVP
MMLLVPVLAGQEGSVAWALVTLTAKTALVVAGVLFLAVRGVPHLLHYVARWRNRELFLLTLLSICFGVAWGTHAAGLSLA
LGAFLAGLVISGSEYEHYAASQVLPLHDLFICFFFVSVGMSLDVGLALTNPLIVLTLTALLMLSKFVLVTGSALLPGLGF
ASAVMTGGMLCQVGEFSFILARLGNEAGLFSGEAMQLFLASAVVTMFLTPWAAGYAGRLGRFLRRRGSSALRDHTGVTST
AQSDHLVIIGYGPGGRHLAQAARLWNIDYVVIDSNPDTVRDERARGVPIMFGDAASETMLEHAGVERARAVAVVVSDPVA
ARTVTALVRELSPDVQIITRARYLGEYDGMREAGANDVVPAEMEASVAMVGRVLERFMVGSDELKAFLERIRAEGYQMDA
EELEKRGKYSFLPFMQLRQVHVEEGSAVQGKTLGELHIRRKYRVAVMAVRHNGTVLPVPGAKTELLPGDEVLLSGCPGDI
GIVASMFSKGGAPLPDENDTIPAGTACPVE

Specific function: Unknown

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=388, Percent_Identity=29.3814432989691, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1786685, Length=536, Percent_Identity=33.955223880597, Blast_Score=239, Evalue=6e-64,
Organism=Escherichia coli, GI1786232, Length=549, Percent_Identity=30.6010928961749, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1789749, Length=511, Percent_Identity=29.9412915851272, Blast_Score=209, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6322367, Length=383, Percent_Identity=25.065274151436, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 71049; Mature: 71049

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLGNLVLVLAFSVGVVLLAQKFRIPAMVGFLLAGVAAGPHALGMVSDVAAVDVLAEIG
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VVLLLFTLGMEFSIARLRALFRVALLGGGTQVAVTALAAGSVAHWLLGIAWNTSVFIGFL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IALSSTAIGIRLMRDKGDVETPHGTAALGILIFQDMAVVPMMLLVPVLAGQEGSVAWALV
HHHHCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TLTAKTALVVAGVLFLAVRGVPHLLHYVARWRNRELFLLTLLSICFGVAWGTHAAGLSLA
EHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
LGAFLAGLVISGSEYEHYAASQVLPLHDLFICFFFVSVGMSLDVGLALTNPLIVLTLTAL
HHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHH
LMLSKFVLVTGSALLPGLGFASAVMTGGMLCQVGEFSFILARLGNEAGLFSGEAMQLFLA
HHHHHHHHHCCCHHHCCCCHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHHHH
SAVVTMFLTPWAAGYAGRLGRFLRRRGSSALRDHTGVTSTAQSDHLVIIGYGPGGRHLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHH
AARLWNIDYVVIDSNPDTVRDERARGVPIMFGDAASETMLEHAGVERARAVAVVVSDPVA
HHHHCCCEEEEECCCCCCCHHHHCCCCCEEECCCHHHHHHHHCCCHHHHEEEEEECCCHH
ARTVTALVRELSPDVQIITRARYLGEYDGMREAGANDVVPAEMEASVAMVGRVLERFMVG
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SDELKAFLERIRAEGYQMDAEELEKRGKYSFLPFMQLRQVHVEEGSAVQGKTLGELHIRR
CHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KYRVAVMAVRHNGTVLPVPGAKTELLPGDEVLLSGCPGDIGIVASMFSKGGAPLPDENDT
EEEEEEEEEECCCEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
IPAGTACPVE
CCCCCCCCCC
>Mature Secondary Structure
MELLGNLVLVLAFSVGVVLLAQKFRIPAMVGFLLAGVAAGPHALGMVSDVAAVDVLAEIG
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VVLLLFTLGMEFSIARLRALFRVALLGGGTQVAVTALAAGSVAHWLLGIAWNTSVFIGFL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IALSSTAIGIRLMRDKGDVETPHGTAALGILIFQDMAVVPMMLLVPVLAGQEGSVAWALV
HHHHCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TLTAKTALVVAGVLFLAVRGVPHLLHYVARWRNRELFLLTLLSICFGVAWGTHAAGLSLA
EHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
LGAFLAGLVISGSEYEHYAASQVLPLHDLFICFFFVSVGMSLDVGLALTNPLIVLTLTAL
HHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHH
LMLSKFVLVTGSALLPGLGFASAVMTGGMLCQVGEFSFILARLGNEAGLFSGEAMQLFLA
HHHHHHHHHCCCHHHCCCCHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHHHH
SAVVTMFLTPWAAGYAGRLGRFLRRRGSSALRDHTGVTSTAQSDHLVIIGYGPGGRHLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHH
AARLWNIDYVVIDSNPDTVRDERARGVPIMFGDAASETMLEHAGVERARAVAVVVSDPVA
HHHHCCCEEEEECCCCCCCHHHHCCCCCEEECCCHHHHHHHHCCCHHHHEEEEEECCCHH
ARTVTALVRELSPDVQIITRARYLGEYDGMREAGANDVVPAEMEASVAMVGRVLERFMVG
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SDELKAFLERIRAEGYQMDAEELEKRGKYSFLPFMQLRQVHVEEGSAVQGKTLGELHIRR
CHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KYRVAVMAVRHNGTVLPVPGAKTELLPGDEVLLSGCPGDIGIVASMFSKGGAPLPDENDT
EEEEEEEEEECCCEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
IPAGTACPVE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]