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The map label for this gene is zraR [H]

Identifier: 78355706

GI number: 78355706

Start: 676075

End: 677505

Strand: Direct

Name: zraR [H]

Synonym: Dde_0659

Alternate gene names: 78355706

Gene position: 676075-677505 (Clockwise)

Preceding gene: 78355705

Following gene: 78355707

Centisome position: 18.12

GC content: 60.94

Gene sequence:

>1431_bases
ATGACCGGAACATCTTCATGCAGCGATTTGGTGGCCGAAGTGGTTGCCACCATTAGTGAAGGGCTGATGCTTGTTTCTCC
GCAGGGCAAGATAGAAATGGTCAATCCCGCGCTGGAGCGTCTGACGGGATATTCCGCTGCGGAGCTGACGGGGCAGCCGT
GCACTGTGCTGGGCTGCGGTGCGTGCGATGAAGCGCGGCGCGGTGCTTCCGGCTGGTGCCGGTTGTTTGAACGCGGGACC
GAGAGCAGCCGCCGGTGTGATATTGTGCGCAAAGACGGTGTGCGGGTGCCGGTTTCAAAAAATGCCCGCGTGGTGCGCAA
GGACGGCCGTGTTGCAGGAGCGGTGGAAACGTTCACCGACATGAGCGAAGTTGTAGAGCGTGACAGGCGCATCGAGGCGC
TGGCACGCATGCTGGACAGGGCTGACGGATTTGCCGGTATGGTGGGTGTTTCTCCGGCCATGCAGCGTGTTTACCGCATC
GTGGAACGCGCTGCGGACAGCGATGCGCCGGTGCTCATACTGGGGCCGTCCGGCTGCGGCAAAGAGCTTGCCGCACGGGC
TGTGCACGATCTGGGACACCGGGCAAACGGCCCGTATGTGCCGCTTAACTGCTCAGCCCTGAATGAATCTTTGCTGGAAA
GTGAACTGTTCGGGCACGCCAGAGGTTCGTTCAGCGGGGCAGTACGCGACAGACAAGGCCGTTTTGAGGCAGCGCACGGG
GGCGATCTTTTTCTGGATGAAGTGGGGGATCTGCCCCTTGCCACGCAGGTCAAGCTGCTGCGCGTGCTTGAGACAAAGCA
TATCGAGCGGGTGGGGGAAAACAGGTCGCGGGCGGTTGATGTACGGATCATCTGTGCCACTCATAGAGATCTCGGCAGCC
TTGTCCGGACAGGACAGTTCCGCGAAGACCTGCTGTTCCGCATCAACGTCATTCCCGTGGTACTGCCTGCGCTGCGTCAG
CGCGCGGAAGATATTCCGCTGCTGGCAGCGCATTTTGTTGCGGGTATCCGGCAGAGAACAGGCAAGGATATCGAAGGGTT
TACTCCTGATGCCATGCACCGCCTGACAGCCTACGACTGGCCGGGCAATGTGCGCGAACTGCGCAGCGCCGTTGAGTATG
CCTTTGTGCTGGCTGACCGCGGGCGGCTGGGGGTGGAACATCTGCCGGCACACATCACGGGAACCCGTGCGGAGTGTTGT
CCTCAGACTCTGCATGTCGCTTCCTTTGCCGGGGAGGATCTGGCTGCACAGCAAGCGGAACAGCGGAATCAGGAACACGA
TGAGCTGCTGCGGGCACTGCGCCGGACCGGTGGCAATATGGCTGCAGCGGCGCGCCTGCTGGGCGTGCACAGAGGCACGG
TGCGTAACAGAATGCTGAAATACGGCATGAACCTGCGTAAGGAAATACGTGACGGAACCACTGAAGGATGA

Upstream 100 bases:

>100_bases
TTATAATCGGAATATTGAACGCATTGTGGGCATGCGGGTTGCCGTGCGTTGTGATAATGTCTAATCATATGGTTAGACAT
ATGTTGAAACGGGAGAAGCA

Downstream 100 bases:

>100_bases
AAACTGGACGCCGCCTCCGGCTATGCCCTGGCGACCACACTGTGCGGCACCTCGGCTGACCGTTGCAGGCCGGTGCCGCG
TGCAACCCCGCCGGAGCGTG

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTGTSSCSDLVAEVVATISEGLMLVSPQGKIEMVNPALERLTGYSAAELTGQPCTVLGCGACDEARRGASGWCRLFERGT
ESSRRCDIVRKDGVRVPVSKNARVVRKDGRVAGAVETFTDMSEVVERDRRIEALARMLDRADGFAGMVGVSPAMQRVYRI
VERAADSDAPVLILGPSGCGKELAARAVHDLGHRANGPYVPLNCSALNESLLESELFGHARGSFSGAVRDRQGRFEAAHG
GDLFLDEVGDLPLATQVKLLRVLETKHIERVGENRSRAVDVRIICATHRDLGSLVRTGQFREDLLFRINVIPVVLPALRQ
RAEDIPLLAAHFVAGIRQRTGKDIEGFTPDAMHRLTAYDWPGNVRELRSAVEYAFVLADRGRLGVEHLPAHITGTRAECC
PQTLHVASFAGEDLAAQQAEQRNQEHDELLRALRRTGGNMAAAARLLGVHRGTVRNRMLKYGMNLRKEIRDGTTEG

Sequences:

>Translated_476_residues
MTGTSSCSDLVAEVVATISEGLMLVSPQGKIEMVNPALERLTGYSAAELTGQPCTVLGCGACDEARRGASGWCRLFERGT
ESSRRCDIVRKDGVRVPVSKNARVVRKDGRVAGAVETFTDMSEVVERDRRIEALARMLDRADGFAGMVGVSPAMQRVYRI
VERAADSDAPVLILGPSGCGKELAARAVHDLGHRANGPYVPLNCSALNESLLESELFGHARGSFSGAVRDRQGRFEAAHG
GDLFLDEVGDLPLATQVKLLRVLETKHIERVGENRSRAVDVRIICATHRDLGSLVRTGQFREDLLFRINVIPVVLPALRQ
RAEDIPLLAAHFVAGIRQRTGKDIEGFTPDAMHRLTAYDWPGNVRELRSAVEYAFVLADRGRLGVEHLPAHITGTRAECC
PQTLHVASFAGEDLAAQQAEQRNQEHDELLRALRRTGGNMAAAARLLGVHRGTVRNRMLKYGMNLRKEIRDGTTEG
>Mature_475_residues
TGTSSCSDLVAEVVATISEGLMLVSPQGKIEMVNPALERLTGYSAAELTGQPCTVLGCGACDEARRGASGWCRLFERGTE
SSRRCDIVRKDGVRVPVSKNARVVRKDGRVAGAVETFTDMSEVVERDRRIEALARMLDRADGFAGMVGVSPAMQRVYRIV
ERAADSDAPVLILGPSGCGKELAARAVHDLGHRANGPYVPLNCSALNESLLESELFGHARGSFSGAVRDRQGRFEAAHGG
DLFLDEVGDLPLATQVKLLRVLETKHIERVGENRSRAVDVRIICATHRDLGSLVRTGQFREDLLFRINVIPVVLPALRQR
AEDIPLLAAHFVAGIRQRTGKDIEGFTPDAMHRLTAYDWPGNVRELRSAVEYAFVLADRGRLGVEHLPAHITGTRAECCP
QTLHVASFAGEDLAAQQAEQRNQEHDELLRALRRTGGNMAAAARLLGVHRGTVRNRMLKYGMNLRKEIRDGTTEG

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=49.2012779552716, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI87082117, Length=363, Percent_Identity=41.8732782369146, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789087, Length=379, Percent_Identity=42.2163588390501, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1788550, Length=336, Percent_Identity=41.6666666666667, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1788905, Length=361, Percent_Identity=40.4432132963989, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=43.9759036144578, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI87082152, Length=301, Percent_Identity=43.8538205980066, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=38.006230529595, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=46.9298245614035, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1786524, Length=333, Percent_Identity=38.7387387387387, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=37.1165644171779, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87081858, Length=325, Percent_Identity=30.4615384615385, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1789828, Length=262, Percent_Identity=36.2595419847328, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51954; Mature: 51823

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50112 PAS ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTSSCSDLVAEVVATISEGLMLVSPQGKIEMVNPALERLTGYSAAELTGQPCTVLGCG
CCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCHHHHHHCCCCHHHCCCCCCEEEECC
ACDEARRGASGWCRLFERGTESSRRCDIVRKDGVRVPVSKNARVVRKDGRVAGAVETFTD
CCHHHHCCHHHHHHHHHHCCCCCHHCCHHHCCCEECCCCCCCEEEECCCCCHHHHHHHHH
MSEVVERDRRIEALARMLDRADGFAGMVGVSPAMQRVYRIVERAADSDAPVLILGPSGCG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCC
KELAARAVHDLGHRANGPYVPLNCSALNESLLESELFGHARGSFSGAVRDRQGRFEAAHG
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEECCCC
GDLFLDEVGDLPLATQVKLLRVLETKHIERVGENRSRAVDVRIICATHRDLGSLVRTGQF
CCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHCCCH
REDLLFRINVIPVVLPALRQRAEDIPLLAAHFVAGIRQRTGKDIEGFTPDAMHRLTAYDW
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
PGNVRELRSAVEYAFVLADRGRLGVEHLPAHITGTRAECCPQTLHVASFAGEDLAAQQAE
CCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHCHHHHHHHHHCCCHHHHHHHH
QRNQEHDELLRALRRTGGNMAAAARLLGVHRGTVRNRMLKYGMNLRKEIRDGTTEG
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TGTSSCSDLVAEVVATISEGLMLVSPQGKIEMVNPALERLTGYSAAELTGQPCTVLGCG
CCCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCHHHHHHCCCCHHHCCCCCCEEEECC
ACDEARRGASGWCRLFERGTESSRRCDIVRKDGVRVPVSKNARVVRKDGRVAGAVETFTD
CCHHHHCCHHHHHHHHHHCCCCCHHCCHHHCCCEECCCCCCCEEEECCCCCHHHHHHHHH
MSEVVERDRRIEALARMLDRADGFAGMVGVSPAMQRVYRIVERAADSDAPVLILGPSGCG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCC
KELAARAVHDLGHRANGPYVPLNCSALNESLLESELFGHARGSFSGAVRDRQGRFEAAHG
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEECCCC
GDLFLDEVGDLPLATQVKLLRVLETKHIERVGENRSRAVDVRIICATHRDLGSLVRTGQF
CCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHCCCH
REDLLFRINVIPVVLPALRQRAEDIPLLAAHFVAGIRQRTGKDIEGFTPDAMHRLTAYDW
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
PGNVRELRSAVEYAFVLADRGRLGVEHLPAHITGTRAECCPQTLHVASFAGEDLAAQQAE
CCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHCHHHHHHHHHCCCHHHHHHHH
QRNQEHDELLRALRRTGGNMAAAARLLGVHRGTVRNRMLKYGMNLRKEIRDGTTEG
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]