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The map label for this gene is speB1 [H]

Identifier: 78355621

GI number: 78355621

Start: 599539

End: 600438

Strand: Direct

Name: speB1 [H]

Synonym: Dde_0574

Alternate gene names: 78355621

Gene position: 599539-600438 (Clockwise)

Preceding gene: 78355620

Following gene: 78355625

Centisome position: 16.07

GC content: 64.11

Gene sequence:

>900_bases
ATGAGTTTGTGCGAACATGAAGAGCGTTTTCTGGACTCCGAGCTGGAGCCTGTGGCGCCCGGAAAGGCGCGGTTTCATAT
TATTCCGGCGGGCTACGAAGCCTCTGTATCGTACGGCGGAGGCACCTTCAGGGGGCCTGCCGCCATTCTGGCCGCATCGC
GGCAGCTGGAGCTGTGGGACGGGCTGTCCGACCCTTCACGGCTGGGGCTGTTCACCCACTGCCCTGTGGACTGCGATGCA
GAAACGGCAGAGGTGCTGATGCGTATCGAAGCCTCGGTGCAGGCCGCGCTGGACGCTGCGCCGGAGAATCCGCCTGTGCC
TGTGCTGCTGGGCGGAGAGCATACCGTCACGCTGGGAGCGCTGAGGGCTTTGTATAAACGGTACGGATCGTTCGGGGTGG
TGCAGTTTGACGCGCATGCCGATCTGAGAGAACGCTACGACGGTACCCCCTACAGCCACGCCTGCGTCATGCGCAGGGCG
CTTGAAATGGGCCTGCCGCTGGTGCAGGTGGGCGTGCGTGCCTGCAGCGAAGAAGAAGTCCGGGTGCGCACGGCACATGG
CGTGACATGCTGGGACGCCCGTCAGCTGGCGGAACACGGCCTGCCGGAGCATATTCTGCCGCCGGACTTTCCCTCGCGGG
TGTATGTGACGTTTGATGTGGACGGGCTGGACCCTGCGGTCATACGCGCCACGGGAACCCCCGTGCCGGGAGGACTGGGC
TGGTGGGACGCTCAGCACATGCTGCGGCAGGCAGTGGAAGGGCGCCATGTCCTTGGTATGGATGTCGTGGAACTGGCACC
GGATCTTGGTGACATTGCCTCGGACTTTGCCGCGGCGCAACTGGTGTACAACATGATGGGCATGGTGCAGCGGCATGCCG
CTGCAAAGGGGCGCGTCTGA

Upstream 100 bases:

>100_bases
CCTTCGGGTACGAAGACTTCAGAAACAGGCTTTCCTGAACCGGTGACCGCCCCGTGCCTTGCGGGGCGGTCTTGCGCGGT
GTGCCGCGCGAGGAGCTGAT

Downstream 100 bases:

>100_bases
CCCTGAGCTGTAGTTCGCCTTGCGCGCCGCTGCCCTCTACGGACATGCATTTTCTATCCGCCGCCGGAAGCCGTTTTTCA
ACGAGCAGTCCGGCGGCGGT

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase 1; AUH 1 [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSLCEHEERFLDSELEPVAPGKARFHIIPAGYEASVSYGGGTFRGPAAILAASRQLELWDGLSDPSRLGLFTHCPVDCDA
ETAEVLMRIEASVQAALDAAPENPPVPVLLGGEHTVTLGALRALYKRYGSFGVVQFDAHADLRERYDGTPYSHACVMRRA
LEMGLPLVQVGVRACSEEEVRVRTAHGVTCWDARQLAEHGLPEHILPPDFPSRVYVTFDVDGLDPAVIRATGTPVPGGLG
WWDAQHMLRQAVEGRHVLGMDVVELAPDLGDIASDFAAAQLVYNMMGMVQRHAAAKGRV

Sequences:

>Translated_299_residues
MSLCEHEERFLDSELEPVAPGKARFHIIPAGYEASVSYGGGTFRGPAAILAASRQLELWDGLSDPSRLGLFTHCPVDCDA
ETAEVLMRIEASVQAALDAAPENPPVPVLLGGEHTVTLGALRALYKRYGSFGVVQFDAHADLRERYDGTPYSHACVMRRA
LEMGLPLVQVGVRACSEEEVRVRTAHGVTCWDARQLAEHGLPEHILPPDFPSRVYVTFDVDGLDPAVIRATGTPVPGGLG
WWDAQHMLRQAVEGRHVLGMDVVELAPDLGDIASDFAAAQLVYNMMGMVQRHAAAKGRV
>Mature_298_residues
SLCEHEERFLDSELEPVAPGKARFHIIPAGYEASVSYGGGTFRGPAAILAASRQLELWDGLSDPSRLGLFTHCPVDCDAE
TAEVLMRIEASVQAALDAAPENPPVPVLLGGEHTVTLGALRALYKRYGSFGVVQFDAHADLRERYDGTPYSHACVMRRAL
EMGLPLVQVGVRACSEEEVRVRTAHGVTCWDARQLAEHGLPEHILPPDFPSRVYVTFDVDGLDPAVIRATGTPVPGGLGW
WDAQHMLRQAVEGRHVLGMDVVELAPDLGDIASDFAAAQLVYNMMGMVQRHAAAKGRV

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=195, Percent_Identity=31.2820512820513, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1789306, Length=252, Percent_Identity=31.7460317460317, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325146, Length=194, Percent_Identity=26.8041237113402, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 32414; Mature: 32283

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLCEHEERFLDSELEPVAPGKARFHIIPAGYEASVSYGGGTFRGPAAILAASRQLELWD
CCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHCCCHHHHC
GLSDPSRLGLFTHCPVDCDAETAEVLMRIEASVQAALDAAPENPPVPVLLGGEHTVTLGA
CCCCHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
LRALYKRYGSFGVVQFDAHADLRERYDGTPYSHACVMRRALEMGLPLVQVGVRACSEEEV
HHHHHHHHCCCCEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCE
RVRTAHGVTCWDARQLAEHGLPEHILPPDFPSRVYVTFDVDGLDPAVIRATGTPVPGGLG
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCC
WWDAQHMLRQAVEGRHVLGMDVVELAPDLGDIASDFAAAQLVYNMMGMVQRHAAAKGRV
HHHHHHHHHHHHCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLCEHEERFLDSELEPVAPGKARFHIIPAGYEASVSYGGGTFRGPAAILAASRQLELWD
CCCHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHCCCHHHHC
GLSDPSRLGLFTHCPVDCDAETAEVLMRIEASVQAALDAAPENPPVPVLLGGEHTVTLGA
CCCCHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
LRALYKRYGSFGVVQFDAHADLRERYDGTPYSHACVMRRALEMGLPLVQVGVRACSEEEV
HHHHHHHHCCCCEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCE
RVRTAHGVTCWDARQLAEHGLPEHILPPDFPSRVYVTFDVDGLDPAVIRATGTPVPGGLG
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCC
WWDAQHMLRQAVEGRHVLGMDVVELAPDLGDIASDFAAAQLVYNMMGMVQRHAAAKGRV
HHHHHHHHHHHHCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]