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The map label for this gene is algB [H]

Identifier: 78355365

GI number: 78355365

Start: 307459

End: 308934

Strand: Direct

Name: algB [H]

Synonym: Dde_0318

Alternate gene names: 78355365

Gene position: 307459-308934 (Clockwise)

Preceding gene: 78355364

Following gene: 78355366

Centisome position: 8.24

GC content: 58.74

Gene sequence:

>1476_bases
GTGAGTGATCGGACTGCAAAAGGCACGGCTTCTGCTGGTGTGACGCCTCTTGTGGAGGGGCTGTTTGCCATGTCGGTGGA
GGCCGGGCCGCTGCTCGATACCATTCCGCTGCCGCTGGCGGTTATTTCGCCGGAGCGTAAGGTATTGTTTATAAACGAGG
CCGCGCAGGTGCTCACCGGTTTTTCTCTGGAAGAAGCCCGCGGTCTGCACTGCATGTATGTCATGCGCAGCAGCCTGTGT
CCGGACAAGTGCCCGCTTGCCAAGGTGGAAGATACGGGTGCCGCTGTCTGTGTCGATGCCAACATAGTCAGCAAGGAACG
CAGGAAGATTCCTGTGCGGGCCACTTTTGCGCCGGTGCTTGCGCCGGACGGGAGCATCGCCGGTTATGTGGAGGCGCTGG
AAGACATACGCATCCTGCAGGAGCTTGAGATAAAGCAGGGCTGGTCGTACGGTTTCGGCGACATGATAGGGCATAGCCAC
GAGATGGAGCGCATCTTTCAGATGGTGCCCGGCATTGCCCAGACAGATTCATCCGTGCTGGTGACCGGTGAGACCGGAAC
CGGCAAAGACCTGCTGGCGGAGGCGATTCACAACGCTTCTGCCAGAGCCAAGGGGCCGTTTGTAAAAGTCAACTGCGGAG
CGCTGCCCGAAACGTTGCTGGAGTCGGAGTTGTTCGGCCATAGCAAGGGGGCGTTCACCGGTGCCACGGAAAGCAAGCCC
GGCCGGTTCCGCATGGCACACAACGGCACGCTTTTTCTGACGGAAATCGGTGATCTGCCGCTTTCGCTGCAGGTGAAGCT
GCTTACTTTTCTGGATGACAAAGTCATTCATCCGCTGGGCAGTACCAAAGGGGTCAACGTGGATGTGCGCATAGTGGCGG
CCACTCACAGGGATCTCAGGCAGATGGTGCGCGAGGGCAAGTTCCGCGAGGATCTTCTGTACCGGCTCAATGTGGTTCGT
TTTCATATGCCCCCCCTGCGCGAGCGCGGTGAGGACATTAATCTTTTCCTGAATCACTTCGTGCATGTGTTCAGCGAGGA
ATTCGGCAAGAAAGTTACCGGATTTTCGCAGGATGCGCTGTATTTTCTGGAAAATTACGCATTTCCCGGCAACGTGCGCG
AATTGCGCAATGTTGTGGAATACTGCGTCAACGTATGCGGTCAGGAAACCATAGAGGTGGAGCATCTGCCGCGGTATCTT
ATGGAGCAGCCGGCTGGTGTGCCTGCCGGAACGGGATACGGCGTGCAGCCTGCCCCCGAAGCGCCCCCTGCGGGCATGAT
GCCCCCGCCCGGCATGCCGGCACCTGTATCTTCTGCGGCGTCGGGCGCCGTCAACTGGGCCGACATGGAGCGCAAGATGA
TTCTGGACGCCCTGCTGCAGGCCAAGGGGCGCAAGAACAGGGCTGCGGAGATTCTGGGCTGGGCACGTTCCACACTGTGG
CGCAAGATGAAGCATTACGAAATAGAATCCTCCTGA

Upstream 100 bases:

>100_bases
ATTGCAAAGTTTTGATACATTCAGTATGTCTCGAATTCATATGATTTGAAACATACCGGTCCGCGTGTCTGCGGTATCCG
GGAAATGCGGGGGTATAGCT

Downstream 100 bases:

>100_bases
TACGCAGGAGGTATAAGGAGACCGCCGGATGGTGGCCTCGGGGGTGGTGTCGGACTATGAATAAAAGGATACTGGTCACG
CTGCACGGCAGCGATGTGGC

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSDRTAKGTASAGVTPLVEGLFAMSVEAGPLLDTIPLPLAVISPERKVLFINEAAQVLTGFSLEEARGLHCMYVMRSSLC
PDKCPLAKVEDTGAAVCVDANIVSKERRKIPVRATFAPVLAPDGSIAGYVEALEDIRILQELEIKQGWSYGFGDMIGHSH
EMERIFQMVPGIAQTDSSVLVTGETGTGKDLLAEAIHNASARAKGPFVKVNCGALPETLLESELFGHSKGAFTGATESKP
GRFRMAHNGTLFLTEIGDLPLSLQVKLLTFLDDKVIHPLGSTKGVNVDVRIVAATHRDLRQMVREGKFREDLLYRLNVVR
FHMPPLRERGEDINLFLNHFVHVFSEEFGKKVTGFSQDALYFLENYAFPGNVRELRNVVEYCVNVCGQETIEVEHLPRYL
MEQPAGVPAGTGYGVQPAPEAPPAGMMPPPGMPAPVSSAASGAVNWADMERKMILDALLQAKGRKNRAAEILGWARSTLW
RKMKHYEIESS

Sequences:

>Translated_491_residues
MSDRTAKGTASAGVTPLVEGLFAMSVEAGPLLDTIPLPLAVISPERKVLFINEAAQVLTGFSLEEARGLHCMYVMRSSLC
PDKCPLAKVEDTGAAVCVDANIVSKERRKIPVRATFAPVLAPDGSIAGYVEALEDIRILQELEIKQGWSYGFGDMIGHSH
EMERIFQMVPGIAQTDSSVLVTGETGTGKDLLAEAIHNASARAKGPFVKVNCGALPETLLESELFGHSKGAFTGATESKP
GRFRMAHNGTLFLTEIGDLPLSLQVKLLTFLDDKVIHPLGSTKGVNVDVRIVAATHRDLRQMVREGKFREDLLYRLNVVR
FHMPPLRERGEDINLFLNHFVHVFSEEFGKKVTGFSQDALYFLENYAFPGNVRELRNVVEYCVNVCGQETIEVEHLPRYL
MEQPAGVPAGTGYGVQPAPEAPPAGMMPPPGMPAPVSSAASGAVNWADMERKMILDALLQAKGRKNRAAEILGWARSTLW
RKMKHYEIESS
>Mature_490_residues
SDRTAKGTASAGVTPLVEGLFAMSVEAGPLLDTIPLPLAVISPERKVLFINEAAQVLTGFSLEEARGLHCMYVMRSSLCP
DKCPLAKVEDTGAAVCVDANIVSKERRKIPVRATFAPVLAPDGSIAGYVEALEDIRILQELEIKQGWSYGFGDMIGHSHE
MERIFQMVPGIAQTDSSVLVTGETGTGKDLLAEAIHNASARAKGPFVKVNCGALPETLLESELFGHSKGAFTGATESKPG
RFRMAHNGTLFLTEIGDLPLSLQVKLLTFLDDKVIHPLGSTKGVNVDVRIVAATHRDLRQMVREGKFREDLLYRLNVVRF
HMPPLRERGEDINLFLNHFVHVFSEEFGKKVTGFSQDALYFLENYAFPGNVRELRNVVEYCVNVCGQETIEVEHLPRYLM
EQPAGVPAGTGYGVQPAPEAPPAGMMPPPGMPAPVSSAASGAVNWADMERKMILDALLQAKGRKNRAAEILGWARSTLWR
KMKHYEIESS

Specific function: Positive regulator of the alginate biosynthetic gene algD [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=345, Percent_Identity=42.6086956521739, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1790299, Length=337, Percent_Identity=43.026706231454, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1789233, Length=336, Percent_Identity=41.6666666666667, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790437, Length=332, Percent_Identity=42.4698795180723, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI1789087, Length=343, Percent_Identity=41.6909620991254, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1788905, Length=237, Percent_Identity=50.6329113924051, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI87082117, Length=235, Percent_Identity=51.4893617021277, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI87082152, Length=229, Percent_Identity=49.7816593886463, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1786524, Length=350, Percent_Identity=38, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87081872, Length=343, Percent_Identity=35.8600583090379, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787583, Length=229, Percent_Identity=41.0480349344978, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI87081858, Length=378, Percent_Identity=28.8359788359788, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=40.625, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53695; Mature: 53563

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRTAKGTASAGVTPLVEGLFAMSVEAGPLLDTIPLPLAVISPERKVLFINEAAQVLTG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHC
FSLEEARGLHCMYVMRSSLCPDKCPLAKVEDTGAAVCVDANIVSKERRKIPVRATFAPVL
CCHHHHCCCCHHHHHHHCCCCCCCCCCEECCCCCEEEEECHHHHHHHHCCCEEEEECCEE
APDGSIAGYVEALEDIRILQELEIKQGWSYGFGDMIGHSHEMERIFQMVPGIAQTDSSVL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCEE
VTGETGTGKDLLAEAIHNASARAKGPFVKVNCGALPETLLESELFGHSKGAFTGATESKP
EECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCC
GRFRMAHNGTLFLTEIGDLPLSLQVKLLTFLDDKVIHPLGSTKGVNVDVRIVAATHRDLR
CCEEEECCCEEEEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHH
QMVREGKFREDLLYRLNVVRFHMPPLRERGEDINLFLNHFVHVFSEEFGKKVTGFSQDAL
HHHHCCCHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHH
YFLENYAFPGNVRELRNVVEYCVNVCGQETIEVEHLPRYLMEQPAGVPAGTGYGVQPAPE
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCC
APPAGMMPPPGMPAPVSSAASGAVNWADMERKMILDALLQAKGRKNRAAEILGWARSTLW
CCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RKMKHYEIESS
HHHHHCCCCCC
>Mature Secondary Structure 
SDRTAKGTASAGVTPLVEGLFAMSVEAGPLLDTIPLPLAVISPERKVLFINEAAQVLTG
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHC
FSLEEARGLHCMYVMRSSLCPDKCPLAKVEDTGAAVCVDANIVSKERRKIPVRATFAPVL
CCHHHHCCCCHHHHHHHCCCCCCCCCCEECCCCCEEEEECHHHHHHHHCCCEEEEECCEE
APDGSIAGYVEALEDIRILQELEIKQGWSYGFGDMIGHSHEMERIFQMVPGIAQTDSSVL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCEE
VTGETGTGKDLLAEAIHNASARAKGPFVKVNCGALPETLLESELFGHSKGAFTGATESKP
EECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCC
GRFRMAHNGTLFLTEIGDLPLSLQVKLLTFLDDKVIHPLGSTKGVNVDVRIVAATHRDLR
CCEEEECCCEEEEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHH
QMVREGKFREDLLYRLNVVRFHMPPLRERGEDINLFLNHFVHVFSEEFGKKVTGFSQDAL
HHHHCCCHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHH
YFLENYAFPGNVRELRNVVEYCVNVCGQETIEVEHLPRYLMEQPAGVPAGTGYGVQPAPE
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCC
APPAGMMPPPGMPAPVSSAASGAVNWADMERKMILDALLQAKGRKNRAAEILGWARSTLW
CCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RKMKHYEIESS
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]