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The map label for this gene is asd [H]

Identifier: 78355301

GI number: 78355301

Start: 236496

End: 237542

Strand: Direct

Name: asd [H]

Synonym: Dde_0254

Alternate gene names: 78355301

Gene position: 236496-237542 (Clockwise)

Preceding gene: 78355300

Following gene: 78355302

Centisome position: 6.34

GC content: 57.88

Gene sequence:

>1047_bases
ATGTCCAAGGAACGTTTGGTCGTTGCGGTTGTAGGTGCCACGGGTGCTGTGGGCCGCGAAATGCTGAAGACGCTGGAAGA
TCGTGAATTTCCCGCTCATGAGGTGCGCGCGCTGGCCTCTGCCCGCAGCGCAGGAACCACCGTACCCTTCAAGGGTGGCG
AGCTCACCGTGCGCGAACTTACCGAAGACTCCTTTGAAGGTGTTGATATCGCATTGTTTTCTGCAGGCGGCGGCACTTCG
GCCCGGTTTGCCCCCCATGCCGTGAAATCCGGCTGCGTGGTGGTGGACAACTCCAGCAACTGGCGCATGGATGAGCGCTG
CCCGCTGGTGGTGCCCGAGGTGAACCCCGACGCCCTCAAGCTGCACAACGGCATCATTGCCAACCCCAACTGCTCGACCA
TCCAGATGGTTGTGGCCCTCAAGCCTCTGCATGATGCGGCAGGCGTACGCCGCGTGGTGGTTTCCACCTATCAGGCTGTT
TCCGGTACCGGCCAGAAGGCCATATCCGAACTGGAAAAACAGGTGCGGCAGATGTTTAACATGCAGGAGCCCGAAGCTTC
GGTCTATCCGTATCAGATAGCGTTCAACTGTCTGCCGCACATCGATGTTTTCCTTGAAGACGGCTACACCAAGGAAGAAC
TGAAGATGGTGCAGGAAACCGTGAAGATAATGGGCGACCCGTCGGTGAAGGTTACCGCCACCACCGTGCGCGTGCCGGTT
TTTTACGGCCATTCCGAATCGCTGAACATCGAAACGGAGAAAAAACTGACCGCGGCGCAGGCCCGCGCCGTGCTGGCGCA
GGCTCCCGGCGTGCGTGTACTGGATAATCCTTCGGAAAATATCTACCCCATGGCCATTCATGCCGCAGGTGAGGATGAAA
CCTTTGTCGGGCGCATCCGTGAAGACCATACCATTGAAAACGGTCTGAACATGTGGGTGGTGGCTGACAACCTGCGCAAA
GGCGCCGCACTTAATGCCGTACAGATTGCCGAAGAACTGGTGGAGCGTTCTCTGCTGGATATCGCCGATCCCGGAAAATT
CCTGTAA

Upstream 100 bases:

>100_bases
GTGATAAGGAGCTGGGCAGATTCCTGCGTTCGCGGGGCGTTACCGCATAGTCCGGAAAACGGGCGGCGGCACATGTTTTT
CCACTCACAAGGAGTTTTTA

Downstream 100 bases:

>100_bases
TACAACGGAGCAGTTGCGTTGATACCTGTTCTTGATACCGATGCGTGGGTGGAAAAGCTGCTTTCGACACGCCGCAGTGC
CGAAGGCAAGATTCTTGCGT

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSKERLVVAVVGATGAVGREMLKTLEDREFPAHEVRALASARSAGTTVPFKGGELTVRELTEDSFEGVDIALFSAGGGTS
ARFAPHAVKSGCVVVDNSSNWRMDERCPLVVPEVNPDALKLHNGIIANPNCSTIQMVVALKPLHDAAGVRRVVVSTYQAV
SGTGQKAISELEKQVRQMFNMQEPEASVYPYQIAFNCLPHIDVFLEDGYTKEELKMVQETVKIMGDPSVKVTATTVRVPV
FYGHSESLNIETEKKLTAAQARAVLAQAPGVRVLDNPSENIYPMAIHAAGEDETFVGRIREDHTIENGLNMWVVADNLRK
GAALNAVQIAEELVERSLLDIADPGKFL

Sequences:

>Translated_348_residues
MSKERLVVAVVGATGAVGREMLKTLEDREFPAHEVRALASARSAGTTVPFKGGELTVRELTEDSFEGVDIALFSAGGGTS
ARFAPHAVKSGCVVVDNSSNWRMDERCPLVVPEVNPDALKLHNGIIANPNCSTIQMVVALKPLHDAAGVRRVVVSTYQAV
SGTGQKAISELEKQVRQMFNMQEPEASVYPYQIAFNCLPHIDVFLEDGYTKEELKMVQETVKIMGDPSVKVTATTVRVPV
FYGHSESLNIETEKKLTAAQARAVLAQAPGVRVLDNPSENIYPMAIHAAGEDETFVGRIREDHTIENGLNMWVVADNLRK
GAALNAVQIAEELVERSLLDIADPGKFL
>Mature_347_residues
SKERLVVAVVGATGAVGREMLKTLEDREFPAHEVRALASARSAGTTVPFKGGELTVRELTEDSFEGVDIALFSAGGGTSA
RFAPHAVKSGCVVVDNSSNWRMDERCPLVVPEVNPDALKLHNGIIANPNCSTIQMVVALKPLHDAAGVRRVVVSTYQAVS
GTGQKAISELEKQVRQMFNMQEPEASVYPYQIAFNCLPHIDVFLEDGYTKEELKMVQETVKIMGDPSVKVTATTVRVPVF
YGHSESLNIETEKKLTAAQARAVLAQAPGVRVLDNPSENIYPMAIHAAGEDETFVGRIREDHTIENGLNMWVVADNLRKG
AALNAVQIAEELVERSLLDIADPGKFL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=335, Percent_Identity=37.6119402985075, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=26.1971830985915, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=394, Percent_Identity=27.9187817258883, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37779; Mature: 37647

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKERLVVAVVGATGAVGREMLKTLEDREFPAHEVRALASARSAGTTVPFKGGELTVREL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
TEDSFEGVDIALFSAGGGTSARFAPHAVKSGCVVVDNSSNWRMDERCPLVVPEVNPDALK
CCCCCCCEEEEEEECCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCEEEECCCCCCEE
LHNGIIANPNCSTIQMVVALKPLHDAAGVRRVVVSTYQAVSGTGQKAISELEKQVRQMFN
ECCCEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
MQEPEASVYPYQIAFNCLPHIDVFLEDGYTKEELKMVQETVKIMGDPSVKVTATTVRVPV
CCCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
FYGHSESLNIETEKKLTAAQARAVLAQAPGVRVLDNPSENIYPMAIHAAGEDETFVGRIR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEECCCCCHHHHHHC
EDHTIENGLNMWVVADNLRKGAALNAVQIAEELVERSLLDIADPGKFL
CCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKERLVVAVVGATGAVGREMLKTLEDREFPAHEVRALASARSAGTTVPFKGGELTVREL
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
TEDSFEGVDIALFSAGGGTSARFAPHAVKSGCVVVDNSSNWRMDERCPLVVPEVNPDALK
CCCCCCCEEEEEEECCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCEEEECCCCCCEE
LHNGIIANPNCSTIQMVVALKPLHDAAGVRRVVVSTYQAVSGTGQKAISELEKQVRQMFN
ECCCEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
MQEPEASVYPYQIAFNCLPHIDVFLEDGYTKEELKMVQETVKIMGDPSVKVTATTVRVPV
CCCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
FYGHSESLNIETEKKLTAAQARAVLAQAPGVRVLDNPSENIYPMAIHAAGEDETFVGRIR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEECCCCCHHHHHHC
EDHTIENGLNMWVVADNLRKGAALNAVQIAEELVERSLLDIADPGKFL
CCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]