Click here to switch to the map view.

The map label for this gene is nrfC [H]

Identifier: 78224702

GI number: 78224702

Start: 3952525

End: 3953298

Strand: Direct

Name: nrfC [H]

Synonym: Gmet_3519

Alternate gene names: 78224702

Gene position: 3952525-3953298 (Clockwise)

Preceding gene: 78224701

Following gene: 78224703

Centisome position: 98.88

GC content: 62.14

Gene sequence:

>774_bases
ATGAATAGACGCGAGTTTCTCAAGCGGAGCATGGTTGTCGTGGCCGGCATGGCGGTGCCGGCGGCGGCCCTACACCTCAT
CGACCCGAAACAGCTTCTGGCAGCAAAGCCGGAACTCCGCTGGGCCTTCCTGGTGGATGCCTACAAGTGCGTCGGCTGCG
GATTCTGCGTCAAGGCGTGCAAACTGGAGAACGAGGTACCCTATGAGGCCAATGTTTCCCGCACCTGGGTGGAGCGCTAT
GTGGTGAAGAAGGACGGTGAAGTCCTGATAGACTCCCCCAAGGCGGCCCGGGATGGGTTCACCACGAAGAAAATCGAGGT
GGGAGAAGGGAAGTTCCGGGAGGTGAAGGACGAGGAGATCGAGAAGGCCTTCTTTGTGCCGAAACTCTGCAACCAGTGCG
AGAATCCCCCCTGCGTTCAGGTCTGTCCCGTGGGGGCCACCTACGCCACGGCGGACGGGGTGGTGCTCGTGGACCGGAAG
TGGTGCATCGGCTGCGGTTACTGCATCATGGGGTGCCCCTACGGGGTCCGCTTCTTCCACCCGGTCCACAAGACGGCGGA
GAAATGCAACTTCTGCTACCACCGGATCACCAAGGGGATGAAGTCGGCCTGCGTCGACGCCTGCCCCTTCGGGGCCCGGC
AGATCGGCAACCTCCGGGACCCCGACGACCCGGTCACCAAGGTGATCATGACCGAGCGGGTCGGCATCCTCAAGGAGGAG
TACGGAACCAAGCCCCAGGTCTACTACATCGGCCTGTCCAAGGAGGTACGCTAG

Upstream 100 bases:

>100_bases
TCGAAGATCCGCGGCATCGATCCCGAGACCCACAATCCCGAGGCCGAATGCAGCCTCTGCCACGACCCCCACCACCCGAA
CCTGGAGGAGCTGAAACGCC

Downstream 100 bases:

>100_bases
CCATGCTGCATGGGGAAGCCTGGACCGTTAAGGAGCTCTTCGTCTATCCCAACGAGTATATCTACTGGACCATCCAGATC
GTCATGTACCCGTTCCTCAC

Product: twin-arginine translocation pathway signal

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNRREFLKRSMVVVAGMAVPAAALHLIDPKQLLAAKPELRWAFLVDAYKCVGCGFCVKACKLENEVPYEANVSRTWVERY
VVKKDGEVLIDSPKAARDGFTTKKIEVGEGKFREVKDEEIEKAFFVPKLCNQCENPPCVQVCPVGATYATADGVVLVDRK
WCIGCGYCIMGCPYGVRFFHPVHKTAEKCNFCYHRITKGMKSACVDACPFGARQIGNLRDPDDPVTKVIMTERVGILKEE
YGTKPQVYYIGLSKEVR

Sequences:

>Translated_257_residues
MNRREFLKRSMVVVAGMAVPAAALHLIDPKQLLAAKPELRWAFLVDAYKCVGCGFCVKACKLENEVPYEANVSRTWVERY
VVKKDGEVLIDSPKAARDGFTTKKIEVGEGKFREVKDEEIEKAFFVPKLCNQCENPPCVQVCPVGATYATADGVVLVDRK
WCIGCGYCIMGCPYGVRFFHPVHKTAEKCNFCYHRITKGMKSACVDACPFGARQIGNLRDPDDPVTKVIMTERVGILKEE
YGTKPQVYYIGLSKEVR
>Mature_257_residues
MNRREFLKRSMVVVAGMAVPAAALHLIDPKQLLAAKPELRWAFLVDAYKCVGCGFCVKACKLENEVPYEANVSRTWVERY
VVKKDGEVLIDSPKAARDGFTTKKIEVGEGKFREVKDEEIEKAFFVPKLCNQCENPPCVQVCPVGATYATADGVVLVDRK
WCIGCGYCIMGCPYGVRFFHPVHKTAEKCNFCYHRITKGMKSACVDACPFGARQIGNLRDPDDPVTKVIMTERVGILKEE
YGTKPQVYYIGLSKEVR

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI2367345, Length=214, Percent_Identity=35.981308411215, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI226510944, Length=222, Percent_Identity=32.4324324324324, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787122, Length=210, Percent_Identity=29.5238095238095, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787872, Length=213, Percent_Identity=28.169014084507, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790326, Length=198, Percent_Identity=29.7979797979798, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787740, Length=118, Percent_Identity=39.8305084745763, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787478, Length=117, Percent_Identity=39.3162393162393, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787749, Length=221, Percent_Identity=28.9592760180996, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789370, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787963, Length=227, Percent_Identity=25.5506607929515, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367245, Length=178, Percent_Identity=29.7752808988764, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082180, Length=107, Percent_Identity=38.3177570093458, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082179, Length=102, Percent_Identity=36.2745098039216, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017567
- InterPro:   IPR006311 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 28789; Mature: 28789

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRREFLKRSMVVVAGMAVPAAALHLIDPKQLLAAKPELRWAFLVDAYKCVGCGFCVKAC
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
KLENEVPYEANVSRTWVERYVVKKDGEVLIDSPKAARDGFTTKKIEVGEGKFREVKDEEI
HCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHCCCCCEEEECCCCCHHHCCHHHH
EKAFFVPKLCNQCENPPCVQVCPVGATYATADGVVLVDRKWCIGCGYCIMGCPYGVRFFH
HHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCEEEEECCHHHCCCHHHHCCCCCHHHHH
PVHKTAEKCNFCYHRITKGMKSACVDACPFGARQIGNLRDPDDPVTKVIMTERVGILKEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGTKPQVYYIGLSKEVR
HCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNRREFLKRSMVVVAGMAVPAAALHLIDPKQLLAAKPELRWAFLVDAYKCVGCGFCVKAC
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
KLENEVPYEANVSRTWVERYVVKKDGEVLIDSPKAARDGFTTKKIEVGEGKFREVKDEEI
HCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHCCCCCEEEECCCCCHHHCCHHHH
EKAFFVPKLCNQCENPPCVQVCPVGATYATADGVVLVDRKWCIGCGYCIMGCPYGVRFFH
HHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCEEEEECCHHHCCCHHHHCCCCCHHHHH
PVHKTAEKCNFCYHRITKGMKSACVDACPFGARQIGNLRDPDDPVTKVIMTERVGILKEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGTKPQVYYIGLSKEVR
HCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]