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The map label for this gene is mdtA [H]

Identifier: 78224320

GI number: 78224320

Start: 3524715

End: 3525827

Strand: Reverse

Name: mdtA [H]

Synonym: Gmet_3128

Alternate gene names: 78224320

Gene position: 3525827-3524715 (Counterclockwise)

Preceding gene: 78224321

Following gene: 78224319

Centisome position: 88.2

GC content: 68.82

Gene sequence:

>1113_bases
ATGAGGATGCGGACAATCACCGTCCTTCTCCTTTTCGCCGCTGCCGTACTGACGTTTTACGGCTGCGGCGGGGGGAAGGA
AGGAGCGGAGAAGAGAGAAAAACCCCCTGTCGTGACCGGGATCGCGGTGGAAAAGGTCGCCGCGGTGACGGTCCCCGAAG
GGATTGAAGCGGTGGGGACGGTGAAGGCCCGCAATGCCGCGGTGATCGCCGCCCGCATCCCCGGTACCGTCACCGGCGTC
TTTGCGGTCGAGGGGGATCGGGTCGGGCGGGGGAAGGTTCTCGTGACCCTGGAGGCCACGGAGAGCACGGCCCAGGCGGC
GGCCGCATCGGCCTCGGCGGAGGAGGCAAGGCGTGGGCTGGAGGAGGCCCGGGCCCGCAAGCGTCTTGCCGACGCCACTT
TTGAACGTTACCACAACCTTTTCAGGGAGGAGGCCGTTACGCGGCAGGAACTGGATAACCGGCGTGCCGACAAGGATGTG
GCCGACCAGGGGGTTGCCCGGGCCGAGGCCAGAGTTGCCGCAGCGCGGGAAGGCGCCCGGGCCGCCGGTGCCGTTGCCGG
CTACACCCGGATCACCGCACCCCTGACCGGGGTGGTCACGGCGAAACAGGTGGAGCGGGGGATGACGGTCTTCCCCGGCA
CGCCGCTTCTCACCGTTGAGGAGGAGGGGAACTACCGCCTTGAGGTGGCGGTTCCCGAGTCCCTGGTGGCCAAGGCCAAG
GTGGGCGCCACGGTGCGGGTGGCCGTGGATGGCGCCGGTGCGGCTGCATCCGGACGCATCGCCGAGGTGGTTCCGGCCGC
CGACCCGGCGAGCCGCACCTTCACCGCCAAGGTGGATATTGCCGGCAAGGGGCTGAAGTCGGGGATGTTCGGCCGGGTCC
TTTTATCCACCGGGGAAAAGAAGGGGATCCTCGTGCCACGGGGGGCGGTGCTGGAGCGGGGCGCCCTCACCTCGGTCTGG
GTGGTTGACGGGCGCAACATCGCCCGGATGCGGCTCGTGAAGCCCGGAGCGGTCCAAGGGGATCGGGTGGAGATCCTGAC
GGGGCTCACCGAGGGCGAGCGGGTCGTGACGAGCGGCATGGAGAAGGTTGTCGAAGGAGCGGAAGTCCGGTAG

Upstream 100 bases:

>100_bases
GCCGGGCGAGGACCGGACTCGTGGAGCGAGAGGCCGACCACCTGCTGGCAACGGCCCGGATATATTACACCGCCGGCATA
TTCCTGAAGGAGATGGCACC

Downstream 100 bases:

>100_bases
CACGGCTCCCATCACCCGTGGGGGGGTGCCTTGAGTGCGTCGCGACGATGACGATACCCGCAGCGGGAGGAGGTACCTTG
TCTGGTTCCTCTGCTTTGTG

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRMRTITVLLLFAAAVLTFYGCGGGKEGAEKREKPPVVTGIAVEKVAAVTVPEGIEAVGTVKARNAAVIAARIPGTVTGV
FAVEGDRVGRGKVLVTLEATESTAQAAAASASAEEARRGLEEARARKRLADATFERYHNLFREEAVTRQELDNRRADKDV
ADQGVARAEARVAAAREGARAAGAVAGYTRITAPLTGVVTAKQVERGMTVFPGTPLLTVEEEGNYRLEVAVPESLVAKAK
VGATVRVAVDGAGAAASGRIAEVVPAADPASRTFTAKVDIAGKGLKSGMFGRVLLSTGEKKGILVPRGAVLERGALTSVW
VVDGRNIARMRLVKPGAVQGDRVEILTGLTEGERVVTSGMEKVVEGAEVR

Sequences:

>Translated_370_residues
MRMRTITVLLLFAAAVLTFYGCGGGKEGAEKREKPPVVTGIAVEKVAAVTVPEGIEAVGTVKARNAAVIAARIPGTVTGV
FAVEGDRVGRGKVLVTLEATESTAQAAAASASAEEARRGLEEARARKRLADATFERYHNLFREEAVTRQELDNRRADKDV
ADQGVARAEARVAAAREGARAAGAVAGYTRITAPLTGVVTAKQVERGMTVFPGTPLLTVEEEGNYRLEVAVPESLVAKAK
VGATVRVAVDGAGAAASGRIAEVVPAADPASRTFTAKVDIAGKGLKSGMFGRVLLSTGEKKGILVPRGAVLERGALTSVW
VVDGRNIARMRLVKPGAVQGDRVEILTGLTEGERVVTSGMEKVVEGAEVR
>Mature_370_residues
MRMRTITVLLLFAAAVLTFYGCGGGKEGAEKREKPPVVTGIAVEKVAAVTVPEGIEAVGTVKARNAAVIAARIPGTVTGV
FAVEGDRVGRGKVLVTLEATESTAQAAAASASAEEARRGLEEARARKRLADATFERYHNLFREEAVTRQELDNRRADKDV
ADQGVARAEARVAAAREGARAAGAVAGYTRITAPLTGVVTAKQVERGMTVFPGTPLLTVEEEGNYRLEVAVPESLVAKAK
VGATVRVAVDGAGAAASGRIAEVVPAADPASRTFTAKVDIAGKGLKSGMFGRVLLSTGEKKGILVPRGAVLERGALTSVW
VVDGRNIARMRLVKPGAVQGDRVEILTGLTEGERVVTSGMEKVVEGAEVR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=359, Percent_Identity=27.8551532033426, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789929, Length=394, Percent_Identity=23.8578680203046, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081796, Length=314, Percent_Identity=24.5222929936306, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38560; Mature: 38560

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMRTITVLLLFAAAVLTFYGCGGGKEGAEKREKPPVVTGIAVEKVAAVTVPEGIEAVGT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEHHHHHEEEEECCCCCHHHEE
VKARNAAVIAARIPGTVTGVFAVEGDRVGRGKVLVTLEATESTAQAAAASASAEEARRGL
EEECCEEEEEEECCCCEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHH
EEARARKRLADATFERYHNLFREEAVTRQELDNRRADKDVADQGVARAEARVAAAREGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
AAGAVAGYTRITAPLTGVVTAKQVERGMTVFPGTPLLTVEEEGNYRLEVAVPESLVAKAK
HHHHHHCHHEECCCHHHHEEHHHHHCCCEEECCCEEEEEECCCCEEEEEECCHHHHHHHH
VGATVRVAVDGAGAAASGRIAEVVPAADPASRTFTAKVDIAGKGLKSGMFGRVLLSTGEK
CCCEEEEEEECCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCC
KGILVPRGAVLERGALTSVWVVDGRNIARMRLVKPGAVQGDRVEILTGLTEGERVVTSGM
CCEEECCCHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHH
EKVVEGAEVR
HHHHCCCCCC
>Mature Secondary Structure
MRMRTITVLLLFAAAVLTFYGCGGGKEGAEKREKPPVVTGIAVEKVAAVTVPEGIEAVGT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEHHHHHEEEEECCCCCHHHEE
VKARNAAVIAARIPGTVTGVFAVEGDRVGRGKVLVTLEATESTAQAAAASASAEEARRGL
EEECCEEEEEEECCCCEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHH
EEARARKRLADATFERYHNLFREEAVTRQELDNRRADKDVADQGVARAEARVAAAREGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
AAGAVAGYTRITAPLTGVVTAKQVERGMTVFPGTPLLTVEEEGNYRLEVAVPESLVAKAK
HHHHHHCHHEECCCHHHHEEHHHHHCCCEEECCCEEEEEECCCCEEEEEECCHHHHHHHH
VGATVRVAVDGAGAAASGRIAEVVPAADPASRTFTAKVDIAGKGLKSGMFGRVLLSTGEK
CCCEEEEEEECCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCC
KGILVPRGAVLERGALTSVWVVDGRNIARMRLVKPGAVQGDRVEILTGLTEGERVVTSGM
CCEEECCCHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHH
EKVVEGAEVR
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA