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The map label for this gene is cat1 [H]

Identifier: 78224237

GI number: 78224237

Start: 3431741

End: 3433336

Strand: Reverse

Name: cat1 [H]

Synonym: Gmet_3044

Alternate gene names: 78224237

Gene position: 3433336-3431741 (Counterclockwise)

Preceding gene: 78224238

Following gene: 78224234

Centisome position: 85.89

GC content: 60.96

Gene sequence:

>1596_bases
ATGTCAGAGTACGGCACACTGCAAGACCGCGTACGTTGCAAGTCACTGCTCAGTAAGGTCATGACCCCCGAGCAAACTGT
CCAGTTTTTCAAGCCGGGCATGAACCTCGGCTGGTCCGGTTTTACCCCGGCCGGTTATCCCAAGGCAGTGCCCATCGCAC
TGGCTGACCACGTTGAGAAGAACAACCTCCAGGGCAAGATGAAGTTCAACCTCTTCATCGGCGCCTCCGTCGGGGCCGAA
ACCGAAGACCGTTGGGCCACCCTCGACATGATCGACCGCCGTTGGCCGTACCAGACCGGCAAGAACATCGCCGCCGGCAT
CAACGAAGGCCGCATCCGGATGGGCGACAAGCACCTCTCTCTTTTCGCCCAGGACCTTGGCTACGGCTTCTACACCAAGG
ACAGCGAAACCGGCAAGCTTGACCTCGCCATCATCGAAGTCTCCGCCATCACCGAGGACGGCGGCCTGGTCCCCACAACC
TCCTGTGGCGTCATCCCCGAAATCCTCATGATCTGCGACAAGATCATCGTCGAGGTGAACACCGGCGAGCCCTCCTTCGA
GGGGATGCACGACATCGTTGTCTGCAACCATCCGCCGAAGCGCCAAATCCTCGGCATCACCCATGCCGGCGAGCGGATCG
GCACCACCTACGTGCCGTGCGACCCGAGCAAGATCATCGCCGTGGTCGAGTCCAAGCACCGGGACAAGGGGCGCGCCTTC
TCCGAGCAGGACGACACCTCCGAGGCCATTGCCAACAACATCATCGACTTCTTCAGCCACGAAGTGAAGATGGGCCGTCT
CCCCAAGAACCTCCTCCCGCTCCAGTCGGGCGTCGGTTCCATCGCCAACGCCGTTATCGGTGGGCTGGCAAAGGGGCCGT
TCACCAACCTGACTGTTTACACCGAGGTTCTTCAGGACACCATGCTTGACCTCTTCGACTCGGGCAAGCTGGACGCCGCT
TCCTCCTGCTCCCTTTCCCTCTCGGAGACTCCGGGATTCCCCCGCTTCTTCGAGAACTGGGATAAGTACTTCGACAAGAT
CACCCTCCGGCCCCTCTCCATCTCCAACGCGCCGGAACCGATCCGCCGCCTCGGGTGCATCGCCATGAACACCCCGGTCG
AGATCGACATCTATGCTCACGCTAACTCCACGCTGGTCGGCGGTACCCGGATGATCAACGGCCTTGGCGGTTCCGGCGAC
TTCCTCCGCAACGGCTTCCTGAAGATCATGCACACCCCGTCGAGCCGGCCGTCCAAGACCGACCCGACCGGTATCTCCTG
CGTGGTGCCGCACTGCTCCCACATCGACCACACCGAGCACGACCTTGACTGCGTCGTTACCGAGCAGGGTCTGGCCGACC
TCCGCGGTATGGCGCCGAAGGACCGGGCCAAGCGGATCATTGAAAAGTGCGCACACCCGGATTACAAGCCGATTCTCAGC
GAGTACCTGGAAATAGCCACCAAAGACTGCCTCGCCAAGAAGGTCGGTCACGAGCCGCAGCTGTGGGACCGCGCCTTCAA
GATGCATCTCAACCTGGCTCAGAACGGCACCATGAAGATCAAGAACTGGGACGTGAAGATCGACCTCTGCGAGTAA

Upstream 100 bases:

>100_bases
TTTGACGGATTTTTCGTTTCAGGTGTTTGGGTAGTGTCAACTTTTGTACCAGCGTTTACAGGCTTTGCTTGTAATCACCA
TCACAAAACGGAGGTAAGAG

Downstream 100 bases:

>100_bases
GATCAACAGTCAGTGCCAGACACGAAAAAAGCCCCGCCGGGAAACCGGCGGGGCTTTTTTCGTGTCTGCGGAGAGGAGCG
ACGGACGCCTTGAAGGAAGT

Product: Acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSEYGTLQDRVRCKSLLSKVMTPEQTVQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEKNNLQGKMKFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSLFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTT
SCGVIPEILMICDKIIVEVNTGEPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKHRDKGRAF
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFTNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSETPGFPRFFENWDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKIMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKDRAKRIIEKCAHPDYKPILS
EYLEIATKDCLAKKVGHEPQLWDRAFKMHLNLAQNGTMKIKNWDVKIDLCE

Sequences:

>Translated_531_residues
MSEYGTLQDRVRCKSLLSKVMTPEQTVQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEKNNLQGKMKFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSLFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTT
SCGVIPEILMICDKIIVEVNTGEPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKHRDKGRAF
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFTNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSETPGFPRFFENWDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKIMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKDRAKRIIEKCAHPDYKPILS
EYLEIATKDCLAKKVGHEPQLWDRAFKMHLNLAQNGTMKIKNWDVKIDLCE
>Mature_530_residues
SEYGTLQDRVRCKSLLSKVMTPEQTVQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEKNNLQGKMKFNLFIGASVGAET
EDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSLFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTTS
CGVIPEILMICDKIIVEVNTGEPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKHRDKGRAFS
EQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFTNLTVYTEVLQDTMLDLFDSGKLDAAS
SCSLSLSETPGFPRFFENWDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDF
LRNGFLKIMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKDRAKRIIEKCAHPDYKPILSE
YLEIATKDCLAKKVGHEPQLWDRAFKMHLNLAQNGTMKIKNWDVKIDLCE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=502, Percent_Identity=41.0358565737052, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319456, Length=525, Percent_Identity=56.3809523809524, Blast_Score=603, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 58494; Mature: 58363

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYGTLQDRVRCKSLLSKVMTPEQTVQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NNLQGKMKFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHH
LFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTTSCGVIPEILMICDKIIVEVN
HHHHHHCCCEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEE
TGEPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKHRDKGRAF
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEECCCCHHHEEEEEHHCCCCCCCCC
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFTNLTVY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSETPGFPRFFENWDKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHEEEEEEECCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHCCCEEEEECCCCCCCCC
DPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKDRAKRIIEKCAHPDYKPILS
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EYLEIATKDCLAKKVGHEPQLWDRAFKMHLNLAQNGTMKIKNWDVKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCEEEEEECEEEEEECC
>Mature Secondary Structure 
SEYGTLQDRVRCKSLLSKVMTPEQTVQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEK
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NNLQGKMKFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHH
LFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTTSCGVIPEILMICDKIIVEVN
HHHHHHCCCEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEE
TGEPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKHRDKGRAF
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEECCCCHHHEEEEEHHCCCCCCCCC
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFTNLTVY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSETPGFPRFFENWDKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHEEEEEEECCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHCCCEEEEECCCCCCCCC
DPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKDRAKRIIEKCAHPDYKPILS
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EYLEIATKDCLAKKVGHEPQLWDRAFKMHLNLAQNGTMKIKNWDVKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCEEEEEECEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]