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The map label for this gene is dsbD [C]

Identifier: 78222668

GI number: 78222668

Start: 1625591

End: 1626811

Strand: Direct

Name: dsbD [C]

Synonym: Gmet_1456

Alternate gene names: 78222668

Gene position: 1625591-1626811 (Clockwise)

Preceding gene: 78222667

Following gene: 78222669

Centisome position: 40.67

GC content: 62.49

Gene sequence:

>1221_bases
ATGAACAGAACAGCCACGTCAAAAATAGTTGCCATGATGCTTGTTGTCGCGGTGGCCATCCCGGCCCTGGCGGCTGAACC
ACGGAATGGGGAGTCGGCCGGGGCCGATGCGGTCCTGACAAAAGCCATCGAGGATGCGCTCGGCAATGGCACGGGCTCCG
TCACTGTTGACCTGCCGCAGGCTGAAGGGAAGGCAAAAGCCGGCGATCTCGTGACGCTCCGCTATACCATGACCACGGCC
GACGGTGCCCTGGTGGCAACCACCGAGGAGTCGGTGGCCGCTGACAAGGGGCGCCCGCGCTCCGTGGCATTCACGGCCCG
AAGCCGCTACCGCCCCGAAGAGATCGTTGCCGGCGGCGAAGGGAATCTTCCGGGGGTGGCAGAGGCGGTCATCGGCATGG
CACCGGGGGAAAAGAAGCATCTGTCTCTCTCCGCCGACAAGGCGTTCGGTGCCCGTGACCCCCAGCGGGTCGTCACCATG
GCGACGGTGAAGAGTCTCCCCCGGACAGTCGCCATTCCGGCGGCTGACTACGTGAAGAATTTCGGTGCCTTGCCGGTGGT
GGGAAAGGAACTTCCGGTGGTTCCCTATTTTCCGGCCAGGGTCATCGAGGTGACCGAGCAGCAGGCAAAGCTGCAACTCC
TCGCCAGGGACGGCGAGCGGTTCACCGAAAGCTTCGGCGCCGTGGAGACGAAGGTGGATGGGGAGTCGGTGAAGATCCGT
CTGGTCCCCACCATCGGCGCTCCCTTTGAGTTCCGTGGGGCACGGGGGACCATCACCGCAGCCGGCGAGGAAAACTTCAC
GGTGGATTTCAACCATCCCCTGGCCGACCGGAGTGTGGTGCTCGATCTTGAAGTGGTTTCGCTGACCAAAGGGGAGAAGC
TCGCGGCCATATCCGTTCCGTGGCTCGAAAATCACGATCAGGGGCTTGAGAAGGCGAAACAAGAAGAGAAGCCCGCAGTG
CTGGTCCTCTACGCCGACTGGTGCCAGTGGTGCAAGAAGCTCTTTGGCGAAACCGCGGAGGATCCGCGGATAAAGGCGGT
TTCCGACCGTTTTGTCTGGATACGGGTGAACTCGGACAAGGAGAAGGCATACAAGGAACAATACGGCCAGGACGGCTATC
CGCTGATCGTACTCCTCGACCGGCAGGGAAAGGTGGCGAAGAAGCTGGACGGCTTCCGCGATGCCGCCGGCCTGCGGGAA
GAGCTGAATGCGCTGCTGTAG

Upstream 100 bases:

>100_bases
ACTACGGCTATCCCTTTGGCGGTGAGTCGCTGCGGTGCGACGTGAAGGCGGAGAGGTCGGAGCAGGTGGGGAAACGCTGA
GAGACAAGGGAGCGGCCACG

Downstream 100 bases:

>100_bases
TTCACAGACTCCTCCATTCAATTCAATGATCTGAAAGGCTTACCGACCATGACCACTATATTTCCGCCGATACCCGACCG
GTTGCGGCCCCTGCTTCGTA

Product: peptidylprolyl isomerase, FKBP-type

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: Protein-Disulfide Reductase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNRTATSKIVAMMLVVAVAIPALAAEPRNGESAGADAVLTKAIEDALGNGTGSVTVDLPQAEGKAKAGDLVTLRYTMTTA
DGALVATTEESVAADKGRPRSVAFTARSRYRPEEIVAGGEGNLPGVAEAVIGMAPGEKKHLSLSADKAFGARDPQRVVTM
ATVKSLPRTVAIPAADYVKNFGALPVVGKELPVVPYFPARVIEVTEQQAKLQLLARDGERFTESFGAVETKVDGESVKIR
LVPTIGAPFEFRGARGTITAAGEENFTVDFNHPLADRSVVLDLEVVSLTKGEKLAAISVPWLENHDQGLEKAKQEEKPAV
LVLYADWCQWCKKLFGETAEDPRIKAVSDRFVWIRVNSDKEKAYKEQYGQDGYPLIVLLDRQGKVAKKLDGFRDAAGLRE
ELNALL

Sequences:

>Translated_406_residues
MNRTATSKIVAMMLVVAVAIPALAAEPRNGESAGADAVLTKAIEDALGNGTGSVTVDLPQAEGKAKAGDLVTLRYTMTTA
DGALVATTEESVAADKGRPRSVAFTARSRYRPEEIVAGGEGNLPGVAEAVIGMAPGEKKHLSLSADKAFGARDPQRVVTM
ATVKSLPRTVAIPAADYVKNFGALPVVGKELPVVPYFPARVIEVTEQQAKLQLLARDGERFTESFGAVETKVDGESVKIR
LVPTIGAPFEFRGARGTITAAGEENFTVDFNHPLADRSVVLDLEVVSLTKGEKLAAISVPWLENHDQGLEKAKQEEKPAV
LVLYADWCQWCKKLFGETAEDPRIKAVSDRFVWIRVNSDKEKAYKEQYGQDGYPLIVLLDRQGKVAKKLDGFRDAAGLRE
ELNALL
>Mature_406_residues
MNRTATSKIVAMMLVVAVAIPALAAEPRNGESAGADAVLTKAIEDALGNGTGSVTVDLPQAEGKAKAGDLVTLRYTMTTA
DGALVATTEESVAADKGRPRSVAFTARSRYRPEEIVAGGEGNLPGVAEAVIGMAPGEKKHLSLSADKAFGARDPQRVVTM
ATVKSLPRTVAIPAADYVKNFGALPVVGKELPVVPYFPARVIEVTEQQAKLQLLARDGERFTESFGAVETKVDGESVKIR
LVPTIGAPFEFRGARGTITAAGEENFTVDFNHPLADRSVVLDLEVVSLTKGEKLAAISVPWLENHDQGLEKAKQEEKPAV
LVLYADWCQWCKKLFGETAEDPRIKAVSDRFVWIRVNSDKEKAYKEQYGQDGYPLIVLLDRQGKVAKKLDGFRDAAGLRE
ELNALL

Specific function: Required To Facilitate The Formation Of Correct Disulfide Bonds In Some Periplasmic Proteins And For The Assembly Of The Periplasmic C-Type Cytochromes. Acts By Transferring Electrons From Cytoplasmic Thioredoxin To The Periplasm, Thereby Maintaining The

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 43655; Mature: 43655

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTATSKIVAMMLVVAVAIPALAAEPRNGESAGADAVLTKAIEDALGNGTGSVTVDLPQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
AEGKAKAGDLVTLRYTMTTADGALVATTEESVAADKGRPRSVAFTARSRYRPEEIVAGGE
CCCCCCCCCEEEEEEEEEECCCEEEEECCHHHHHCCCCCCEEEEEHHHCCCHHHEEECCC
GNLPGVAEAVIGMAPGEKKHLSLSADKAFGARDPQRVVTMATVKSLPRTVAIPAADYVKN
CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHH
FGALPVVGKELPVVPYFPARVIEVTEQQAKLQLLARDGERFTESFGAVETKVDGESVKIR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEECCCEEEEE
LVPTIGAPFEFRGARGTITAAGEENFTVDFNHPLADRSVVLDLEVVSLTKGEKLAAISVP
EEEECCCCEEECCCCEEEEECCCCCEEEECCCCCCCCEEEEEEEEEEECCCCEEEEEECC
WLENHDQGLEKAKQEEKPAVLVLYADWCQWCKKLFGETAEDPRIKAVSDRFVWIRVNSDK
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCH
EKAYKEQYGQDGYPLIVLLDRQGKVAKKLDGFRDAAGLREELNALL
HHHHHHHHCCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRTATSKIVAMMLVVAVAIPALAAEPRNGESAGADAVLTKAIEDALGNGTGSVTVDLPQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
AEGKAKAGDLVTLRYTMTTADGALVATTEESVAADKGRPRSVAFTARSRYRPEEIVAGGE
CCCCCCCCCEEEEEEEEEECCCEEEEECCHHHHHCCCCCCEEEEEHHHCCCHHHEEECCC
GNLPGVAEAVIGMAPGEKKHLSLSADKAFGARDPQRVVTMATVKSLPRTVAIPAADYVKN
CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHH
FGALPVVGKELPVVPYFPARVIEVTEQQAKLQLLARDGERFTESFGAVETKVDGESVKIR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEECCCEEEEE
LVPTIGAPFEFRGARGTITAAGEENFTVDFNHPLADRSVVLDLEVVSLTKGEKLAAISVP
EEEECCCCEEECCCCEEEEECCCCCEEEECCCCCCCCEEEEEEEEEEECCCCEEEEEECC
WLENHDQGLEKAKQEEKPAVLVLYADWCQWCKKLFGETAEDPRIKAVSDRFVWIRVNSDK
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCH
EKAYKEQYGQDGYPLIVLLDRQGKVAKKLDGFRDAAGLREELNALL
HHHHHHHHCCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA