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The map label for this gene is yfbG [C]

Identifier: 78222643

GI number: 78222643

Start: 1601768

End: 1602709

Strand: Direct

Name: yfbG [C]

Synonym: Gmet_1431

Alternate gene names: 78222643

Gene position: 1601768-1602709 (Clockwise)

Preceding gene: 78222642

Following gene: 78222644

Centisome position: 40.07

GC content: 57.75

Gene sequence:

>942_bases
ATGCGTGTTCTGGTAACCGGCGGGGCAGGGTTCATTGGCTCCCATCTGTGCGAGCGGTTGGTCAGTGACGGCCACGAGGT
TCTCTGTGTCGATAACTTCTTTACGGGGAGCAAACAAAACATCCTGCCGCTCTTGGGAAACCCCCGTTTCGAGTTGATCC
GCCACGATATAACCGAGCCGATTCTTCTGGAGGTGGACCAGATATATCATCTGGCCTGTCCCGCTTCGCCGGTCCATTAT
CAGTACAACCCGGTGAAGACCATCAAGACAAGCGTCATGGGGACCATCAACATGCTTGGCCTCGCCAAGCGGGTCCGGGC
GCGAATCCTTCTGGCCTCCACCTCTGAAGTCTACGGCGATCCCCAGGTGCATCCGCAGCCCGAGACCTACTGGGGGAACG
TTAACCCCATCGGAATCCGCAGCTGCTACGACGAAGGGAAGCGGGTTGCGGAAACCCTCATGATGGATTACCATCGCCAG
AATGGTGTCGACATCCGCATCGTCCGGATTTTCAACACCTTTGGCCCCCGCATGGCCGAGCATGACGGCAGGGTGGTGTC
GAACTTCATTGTTCAGGCTCTCAAAGGGGAAGACATAACGGTCTATGGCGACGGCAGCCAGACCCGCTCCTTCTGCTATG
TGAGCGACTTGGTGGAAGGGCTTGTCCGGACGATGTCATGTGAAGGCTTCACCGGTCCGGTCAACCTGGGCAACCCCGGT
GAAACTACTATCCTGGAATTTGCCCGGCGCATAATCGCACTGACCGGTTCCCAGTCGCAGATTGTTTTCAGGCCTCTCCC
GTCGGATGACCCCAAGCAGCGCCAACCCGATATAACCCTCGCCCGGACGACGCTTGGATGGGAGCCTATCGTGCCCCTGG
AAACGGGTCTCACAAAGACAGTTGATTATTTCTCCGGCCTCGGTGCCGGTTCGGGTTCATGA

Upstream 100 bases:

>100_bases
CCGGAACCTCTACAATCCGCGGCGGATGAAGGAGATCGGCTTCACGTACCACTCCATCGGCCGTAACGGTTCGGCCTTTA
CCGGTTAGCAGGAGCAAGCA

Downstream 100 bases:

>100_bases
CCAAAGGAGGAAGCATGCGGAAGCGGATGTACCTCGTCCCTGCCGGCTGCATACTCTTCATTCTCTTCTTCACCGTTTTC
GGCGAGCGGGGACTTCTGCG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRVLVTGGAGFIGSHLCERLVSDGHEVLCVDNFFTGSKQNILPLLGNPRFELIRHDITEPILLEVDQIYHLACPASPVHY
QYNPVKTIKTSVMGTINMLGLAKRVRARILLASTSEVYGDPQVHPQPETYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQ
NGVDIRIVRIFNTFGPRMAEHDGRVVSNFIVQALKGEDITVYGDGSQTRSFCYVSDLVEGLVRTMSCEGFTGPVNLGNPG
ETTILEFARRIIALTGSQSQIVFRPLPSDDPKQRQPDITLARTTLGWEPIVPLETGLTKTVDYFSGLGAGSGS

Sequences:

>Translated_313_residues
MRVLVTGGAGFIGSHLCERLVSDGHEVLCVDNFFTGSKQNILPLLGNPRFELIRHDITEPILLEVDQIYHLACPASPVHY
QYNPVKTIKTSVMGTINMLGLAKRVRARILLASTSEVYGDPQVHPQPETYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQ
NGVDIRIVRIFNTFGPRMAEHDGRVVSNFIVQALKGEDITVYGDGSQTRSFCYVSDLVEGLVRTMSCEGFTGPVNLGNPG
ETTILEFARRIIALTGSQSQIVFRPLPSDDPKQRQPDITLARTTLGWEPIVPLETGLTKTVDYFSGLGAGSGS
>Mature_313_residues
MRVLVTGGAGFIGSHLCERLVSDGHEVLCVDNFFTGSKQNILPLLGNPRFELIRHDITEPILLEVDQIYHLACPASPVHY
QYNPVKTIKTSVMGTINMLGLAKRVRARILLASTSEVYGDPQVHPQPETYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQ
NGVDIRIVRIFNTFGPRMAEHDGRVVSNFIVQALKGEDITVYGDGSQTRSFCYVSDLVEGLVRTMSCEGFTGPVNLGNPG
ETTILEFARRIIALTGSQSQIVFRPLPSDDPKQRQPDITLARTTLGWEPIVPLETGLTKTVDYFSGLGAGSGS

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=303, Percent_Identity=65.6765676567657, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI7657641, Length=330, Percent_Identity=27.8787878787879, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4507709, Length=318, Percent_Identity=25.1572327044025, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788589, Length=339, Percent_Identity=27.7286135693215, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=26.8436578171091, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=26.1261261261261, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=25.5882352941176, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788365, Length=325, Percent_Identity=24.6153846153846, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788366, Length=238, Percent_Identity=30.2521008403361, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539532, Length=304, Percent_Identity=62.828947368421, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=26.4880952380952, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115532424, Length=327, Percent_Identity=25.9938837920489, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982038, Length=337, Percent_Identity=25.5192878338279, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=335, Percent_Identity=25.3731343283582, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=292, Percent_Identity=23.972602739726, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=64.1935483870968, Blast_Score=415, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34524; Mature: 34524

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTGGAGFIGSHLCERLVSDGHEVLCVDNFFTGSKQNILPLLGNPRFELIRHDITEP
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCHHHHHHHHCCCH
ILLEVDQIYHLACPASPVHYQYNPVKTIKTSVMGTINMLGLAKRVRARILLASTSEVYGD
HHHHHHHHHEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHCCC
PQVHPQPETYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQNGVDIRIVRIFNTFGPRMAE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCHHHH
HDGRVVSNFIVQALKGEDITVYGDGSQTRSFCYVSDLVEGLVRTMSCEGFTGPVNLGNPG
CCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ETTILEFARRIIALTGSQSQIVFRPLPSDDPKQRQPDITLARTTLGWEPIVPLETGLTKT
HHHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHH
VDYFSGLGAGSGS
HHHHHCCCCCCCC
>Mature Secondary Structure
MRVLVTGGAGFIGSHLCERLVSDGHEVLCVDNFFTGSKQNILPLLGNPRFELIRHDITEP
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCHHHHHHHHCCCH
ILLEVDQIYHLACPASPVHYQYNPVKTIKTSVMGTINMLGLAKRVRARILLASTSEVYGD
HHHHHHHHHEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHCCC
PQVHPQPETYWGNVNPIGIRSCYDEGKRVAETLMMDYHRQNGVDIRIVRIFNTFGPRMAE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCHHHH
HDGRVVSNFIVQALKGEDITVYGDGSQTRSFCYVSDLVEGLVRTMSCEGFTGPVNLGNPG
CCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ETTILEFARRIIALTGSQSQIVFRPLPSDDPKQRQPDITLARTTLGWEPIVPLETGLTKT
HHHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHH
VDYFSGLGAGSGS
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]