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The map label for this gene is infC

Identifier: 78222624

GI number: 78222624

Start: 1581445

End: 1581876

Strand: Direct

Name: infC

Synonym: Gmet_1412

Alternate gene names: 78222624

Gene position: 1581445-1581876 (Clockwise)

Preceding gene: 78222623

Following gene: 78222625

Centisome position: 39.56

GC content: 50.23

Gene sequence:

>432_bases
ATGCCATTAAATGAGGCTCTCGCACTTGCGGAGAGTCAGCAGCTTGATCTTGTCGAGGTTTCTCCCACGGCCGTTCCTCC
TGTCTGCCGGATCATGGACTATGGTAAGTTCAAGTATCAGCAGAGCAAGAAGCTGCAGGAAGCCAAGAAGAAGCAATCAC
ACGTCGTGGTTAAGGAAGTAAAGCTTCGCCCCAAGACCGATGAGCATGATCTCCAGTTCAAGATCAAACACGTGCGTCGC
TTCATCGAAGAGGGGAACAAGGCAAAGGTGACTCTCGTATTTCGTGGCCGTGAAATTACGCATATGGAATTCGGGGTTCG
CGCCCTTGAGCGGGTTGCCAGTGAGATTGAAGATATCGCTGTCATCGAGATGAAGCCGAAGATGGAAGGGCGGAGTATGT
TCATGATAGTCGCCCCCAAAGTAAAAAAATAG

Upstream 100 bases:

>100_bases
AGGAGGTGGCGCCATAGCCAAGCCGACCGTAAATGTAAACCAAGCTATCAGAGCCCGTGAGATACGGGTTGTTGGAGCCA
ATAGCGAGCAGCTTGGTATT

Downstream 100 bases:

>100_bases
ATTTTGTTACACTTATAGAAAAGGAGAAAAGTAATGCCCAAGATCAAGACAAACCGTGGCGCAGCCAAGCGTTTCAGGAA
GACTGCCAGCGGTAAAATCA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MPLNEALALAESQQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEAKKKQSHVVVKEVKLRPKTDEHDLQFKIKHVRR
FIEEGNKAKVTLVFRGREITHMEFGVRALERVASEIEDIAVIEMKPKMEGRSMFMIVAPKVKK

Sequences:

>Translated_143_residues
MPLNEALALAESQQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEAKKKQSHVVVKEVKLRPKTDEHDLQFKIKHVRR
FIEEGNKAKVTLVFRGREITHMEFGVRALERVASEIEDIAVIEMKPKMEGRSMFMIVAPKVKK
>Mature_142_residues
PLNEALALAESQQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEAKKKQSHVVVKEVKLRPKTDEHDLQFKIKHVRRF
IEEGNKAKVTLVFRGREITHMEFGVRALERVASEIEDIAVIEMKPKMEGRSMFMIVAPKVKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=142, Percent_Identity=55.6338028169014, Blast_Score=145, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_GEOMG (Q39VS8)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384371.1
- ProteinModelPortal:   Q39VS8
- SMR:   Q39VS8
- STRING:   Q39VS8
- GeneID:   3738939
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1412
- NMPDR:   fig|269799.3.peg.1253
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- PhylomeDB:   Q39VS8
- ProtClustDB:   PRK00028
- BioCyc:   GMET269799:GMET_1412-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 16502; Mature: 16371

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNEALALAESQQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEAKKKQSHVVVKEV
CCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEE
KLRPKTDEHDLQFKIKHVRRFIEEGNKAKVTLVFRGREITHMEFGVRALERVASEIEDIA
ECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHEE
VIEMKPKMEGRSMFMIVAPKVKK
EEEECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
PLNEALALAESQQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEAKKKQSHVVVKEV
CCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEE
KLRPKTDEHDLQFKIKHVRRFIEEGNKAKVTLVFRGREITHMEFGVRALERVASEIEDIA
ECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHEE
VIEMKPKMEGRSMFMIVAPKVKK
EEEECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA