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The map label for this gene is kdsC [H]

Identifier: 78222493

GI number: 78222493

Start: 1440612

End: 1441127

Strand: Direct

Name: kdsC [H]

Synonym: Gmet_1279

Alternate gene names: 78222493

Gene position: 1440612-1441127 (Clockwise)

Preceding gene: 78222492

Following gene: 78222494

Centisome position: 36.04

GC content: 54.26

Gene sequence:

>516_bases
ATGAAAGAGCGTCTCAGCAAAATACGGCTTCTTCTCCTCGATGTGGACGGCGTCATGACCGACGGTCGGATTATCTTCGA
TTCCAACGGAATTGAGAGCAAATTCTTCAACGTCAAGGATGGTCATGGCATCAAAATGGTTCAGAGGGCAGGGATTGAGG
TGGGAATCATTTCGGGCCGCGGGTCGGTGGTCGTGTCTAACCGGGCTGCGGAACTGGGGATTTCTCTTGTCTACCAAAAG
TCCCTCGACAAACTAACCCCGTACCGGGAGATTCTGGGAAAAACCGGATTCACCGATGATCAGGTTGCCTTCGTGGGAGA
TGATGTCATCGATATCCCGGTGTTGCGCCGGGTCGGCTTTGCGGCGGCTCCGGCCGATGCCGTGGAGGATGTTTTTCCTC
ATGTCCACTTCACTACCCGCAATCGCGGTGGCTGGGGAGCCGTTCGCGAAGTCTGTGATCTGCTGCTCAGGGGGCAGGGG
AAATGGGATGAGATAACAGCACGTTATTTTAGTTGA

Upstream 100 bases:

>100_bases
AGTATTCCATTACTTCACTGTTTGTCTTTGAGGGTGACGACGATGCGCAACCGGTTGGAGTCATCCACCTGCATGACCTC
CTTAAAGCGGGGCTGGCCTG

Downstream 100 bases:

>100_bases
TTTTCAGCTTTCTCGCCTAAGGTTCATTCCACCCATCAACTCCCTCCTGCTGGTTACGCACCCAACTCTCGGCTTACGAA
AATTACATCAGCCCATACTC

Product: phosphatase kdsC

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKERLSKIRLLLLDVDGVMTDGRIIFDSNGIESKFFNVKDGHGIKMVQRAGIEVGIISGRGSVVVSNRAAELGISLVYQK
SLDKLTPYREILGKTGFTDDQVAFVGDDVIDIPVLRRVGFAAAPADAVEDVFPHVHFTTRNRGGWGAVREVCDLLLRGQG
KWDEITARYFS

Sequences:

>Translated_171_residues
MKERLSKIRLLLLDVDGVMTDGRIIFDSNGIESKFFNVKDGHGIKMVQRAGIEVGIISGRGSVVVSNRAAELGISLVYQK
SLDKLTPYREILGKTGFTDDQVAFVGDDVIDIPVLRRVGFAAAPADAVEDVFPHVHFTTRNRGGWGAVREVCDLLLRGQG
KWDEITARYFS
>Mature_171_residues
MKERLSKIRLLLLDVDGVMTDGRIIFDSNGIESKFFNVKDGHGIKMVQRAGIEVGIISGRGSVVVSNRAAELGISLVYQK
SLDKLTPYREILGKTGFTDDQVAFVGDDVIDIPVLRRVGFAAAPADAVEDVFPHVHFTTRNRGGWGAVREVCDLLLRGQG
KWDEITARYFS

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=158, Percent_Identity=34.1772151898734, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI2367202, Length=161, Percent_Identity=49.6894409937888, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18866; Mature: 18866

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERLSKIRLLLLDVDGVMTDGRIIFDSNGIESKFFNVKDGHGIKMVQRAGIEVGIISGR
CHHHHHHHEEEEEECCCEEECCEEEEECCCCCCCEEECCCCCCHHHHHHCCCEEEEEECC
GSVVVSNRAAELGISLVYQKSLDKLTPYREILGKTGFTDDQVAFVGDDVIDIPVLRRVGF
CCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECCCEECHHHHHHCCC
AAAPADAVEDVFPHVHFTTRNRGGWGAVREVCDLLLRGQGKWDEITARYFS
CCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKERLSKIRLLLLDVDGVMTDGRIIFDSNGIESKFFNVKDGHGIKMVQRAGIEVGIISGR
CHHHHHHHEEEEEECCCEEECCEEEEECCCCCCCEEECCCCCCHHHHHHCCCEEEEEECC
GSVVVSNRAAELGISLVYQKSLDKLTPYREILGKTGFTDDQVAFVGDDVIDIPVLRRVGF
CCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECCCEECHHHHHHCCC
AAAPADAVEDVFPHVHFTTRNRGGWGAVREVCDLLLRGQGKWDEITARYFS
CCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]