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The map label for this gene is 78222396

Identifier: 78222396

GI number: 78222396

Start: 1306210

End: 1307772

Strand: Direct

Name: 78222396

Synonym: Gmet_1180

Alternate gene names: NA

Gene position: 1306210-1307772 (Clockwise)

Preceding gene: 78222395

Following gene: 78222397

Centisome position: 32.68

GC content: 54.06

Gene sequence:

>1563_bases
TTGAAGATAGAAATCGCCATTGTCCTAATCCTTGCAGCCGCCGGGCTTGGATACTTTGTGGGAAACATGCTGCGCAAGCG
TATTTCCGACACCCTCGTCAGCAAGGCAGAAGAGCTTGCGTCAAAGATTGTCGATGACGCAAAGCGTGAAGCGGAAACGA
TAACCAAGGAAGCAGAACTCAAGGCCAAGGATGAAGTATTTCAGGCAAAGGCTGAGGCGGAGCGAGATGCCAAGGAGAAG
CGCAAGGATCTTCAGGCCCTGGAAAAACGTCTCCAGCAGAAGGAAGAGAATCTCGATAAGAAGATGAACCTCTTTGACCA
ACGCGACGCTGACCTTACGAAAAAGGATCAGGCGCTTCTTAACCGTGAGCAAGGACTTGTTCAGAAGGAAGAGAGGCTTG
ACGGTCTCATTGCGGAGCAAAGGGAAAAACTTGAGAGTATTTCCGGCCTTTCGTCTACAGAGGCAAAGAAAATCCTCATG
GATGCCATGGAGAGCGAGGCCAAGCTCGATGCCGCCAAGCGGATCAAGGTCATCGAGGAGGAGGCTCGCGAAACGGCCGA
CAAGAAGTCGAAGGAGATAATGGCCCTGGCCATCCAACGTTACGCGGGCGAGTACGTTGCCGAGCGGTCCGTGTCGGTTG
TGGCGCTCCCTTCGGATGAGATGAAAGGGCGGATTATAGGTCGTGAAGGCCGGAATATCAGGGCATTGGAGGCTGCTACC
GGTATTGATCTCATCATCGATGACACTCCCGAGGCGGTTATTCTGTCCGGTTTCAACCCGGTTCGCCGCGAAGTGGCAAA
GATTGCCCTGGAAAAACTCATCACTGATGGCCGCATTCATCCCGGCCGCATCGAAGAGGTTGTGGCCAAGGCCGAAGAGG
AAGTTGAGCAGACTATCAAAGAAGCCGGCGATCAGGCTGCTTTCGACCTTGGTGTGCACGGCATTCACCCTGAAATATTG
AAGCTGATCGGTCGCCTCAAGTATCGCACCTCTTACAGCCAGAATGTTTACCAACACTCTCTTGAGGTTGCGTTCCTCTG
CGGCATCATGGCTTCCGAGCTTGGTATCAACGTTAAGCAAGCCAAGCGCGCCGGCCTTCTTCACGATTTGGGCAAGGCGG
TTGATCACGAGGTCGAGGGATCCCACGCGGTTATTGGCGCGGAGCTTGCGCGCAAGTATGGCGAATCCCCGAAGATCGTT
CACGCTATCATGGCCCACCACGAAGACGAGAAGCCCAATACCGTTCTTGCGGTTCTTGTTCAAGCCGCCGATGCTTTGTC
CGGTGCCCGCCCCGGAGCCCGGCGCGAGATGATGGAAACATACGTGAAACGCCTTGATGATCTGGAGCGTATTGCCACAT
CGTTTGTCGGAGTCAACAATTCCTTCGCCATTCAGGCAGGACGCGAAATCAGGGTTATGGTTTCGAGCGATGAAGTCACC
GACGAGCGGGCTGTTGTTCTCGCTAAAGACATAGCAAAGAAGATCGAAGCCGAGATGACCTACCCGGGGCAGATCAAGGT
TAACGTGATCCGGGAAACCCGGGCCATTGAGTATGCCCGTTAA

Upstream 100 bases:

>100_bases
TGTCGCGGAATCCCATGACGTCGCAGTCGATGTCATTATCACCGAGAAGAGAGTTATCACTCTTCACGGTTATCAATAGA
TCAAGGGAGGTATCAAGACA

Downstream 100 bases:

>100_bases
TATCCTTTTTATTGGTGATATCGTTGGCGCCCCGGGCCGTCAGGCCGTGTCCCGCGAGCTCCACCGCCTCATTGACCGTT
ACCGGATAGATCTGGTCATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKIEIAIVLILAAAGLGYFVGNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAELKAKDEVFQAKAEAERDAKEK
RKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALLNREQGLVQKEERLDGLIAEQREKLESISGLSSTEAKKILM
DAMESEAKLDAAKRIKVIEEEARETADKKSKEIMALAIQRYAGEYVAERSVSVVALPSDEMKGRIIGREGRNIRALEAAT
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQTIKEAGDQAAFDLGVHGIHPEIL
KLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIV
HAIMAHHEDEKPNTVLAVLVQAADALSGARPGARREMMETYVKRLDDLERIATSFVGVNNSFAIQAGREIRVMVSSDEVT
DERAVVLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR

Sequences:

>Translated_520_residues
MKIEIAIVLILAAAGLGYFVGNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAELKAKDEVFQAKAEAERDAKEK
RKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALLNREQGLVQKEERLDGLIAEQREKLESISGLSSTEAKKILM
DAMESEAKLDAAKRIKVIEEEARETADKKSKEIMALAIQRYAGEYVAERSVSVVALPSDEMKGRIIGREGRNIRALEAAT
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQTIKEAGDQAAFDLGVHGIHPEIL
KLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIV
HAIMAHHEDEKPNTVLAVLVQAADALSGARPGARREMMETYVKRLDDLERIATSFVGVNNSFAIQAGREIRVMVSSDEVT
DERAVVLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
>Mature_520_residues
MKIEIAIVLILAAAGLGYFVGNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAELKAKDEVFQAKAEAERDAKEK
RKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALLNREQGLVQKEERLDGLIAEQREKLESISGLSSTEAKKILM
DAMESEAKLDAAKRIKVIEEEARETADKKSKEIMALAIQRYAGEYVAERSVSVVALPSDEMKGRIIGREGRNIRALEAAT
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQTIKEAGDQAAFDLGVHGIHPEIL
KLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIV
HAIMAHHEDEKPNTVLAVLVQAADALSGARPGARREMMETYVKRLDDLERIATSFVGVNNSFAIQAGREIRVMVSSDEVT
DERAVVLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_GEOMG (Q39WF6)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384143.1
- ProteinModelPortal:   Q39WF6
- SMR:   Q39WF6
- STRING:   Q39WF6
- GeneID:   3739953
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1180
- NMPDR:   fig|269799.3.peg.1748
- eggNOG:   COG1418
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   GMET269799:GMET_1180-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 57742; Mature: 57742

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1167bb44)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEIAIVLILAAAGLGYFVGNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAEL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKDEVFQAKAEAERDAKEKRKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NREQGLVQKEERLDGLIAEQREKLESISGLSSTEAKKILMDAMESEAKLDAAKRIKVIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARETADKKSKEIMALAIQRYAGEYVAERSVSVVALPSDEMKGRIIGREGRNIRALEAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEECCCCCCEEEEHHCC
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQTIK
CCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EAGDQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQ
HCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIVHAIMAHHEDEKPNTVLAVLV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
QAADALSGARPGARREMMETYVKRLDDLERIATSFVGVNNSFAIQAGREIRVMVSSDEVT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCCCC
DERAVVLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCH
>Mature Secondary Structure
MKIEIAIVLILAAAGLGYFVGNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAEL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKDEVFQAKAEAERDAKEKRKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NREQGLVQKEERLDGLIAEQREKLESISGLSSTEAKKILMDAMESEAKLDAAKRIKVIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARETADKKSKEIMALAIQRYAGEYVAERSVSVVALPSDEMKGRIIGREGRNIRALEAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEECCCCCCEEEEHHCC
GIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQTIK
CCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EAGDQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQ
HCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIVHAIMAHHEDEKPNTVLAVLV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
QAADALSGARPGARREMMETYVKRLDDLERIATSFVGVNNSFAIQAGREIRVMVSSDEVT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCCCC
DERAVVLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA