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The map label for this gene is argD [H]

Identifier: 78188481

GI number: 78188481

Start: 585934

End: 587130

Strand: Reverse

Name: argD [H]

Synonym: Cag_0503

Alternate gene names: 78188481

Gene position: 587130-585934 (Counterclockwise)

Preceding gene: 78188487

Following gene: 78188480

Centisome position: 22.83

GC content: 46.62

Gene sequence:

>1197_bases
ATGAATCCTTTACCGGTAACTCAAGAAACCGAGCAACAGCTTTTTTTTCATAACTATGCCCGTTTACCGCTTGCCATTAC
GCATGGCGAAGGCGTGTGGCTTGTAAGTGCCGATGGCACTCGCTACCTCGATATGATTTCGGGCATTGGCGTTAATGCCC
TTGGTTATGGCGATCGCCGATTGGTTGAGGCAATTAGTGCCCAAGCCTCAAAGCTGATTCATGCGTCGAATCTTTTTTTG
CTTCAGCCGCAATTTGAGTTGGCTGAAAAGTTGCTTGCGCTGTCAGGCATGTCGAAAGTATTTTTTGCTAACAGCGGCAC
AGAGGCGGTTGAAGCTGCCATCAAGATTGCTCGTAAATGGGCTGGGCAGTTGGGTAAACCCAATAAAAAAGAGGTGCTCT
CATTAAGCAATTGCTTTCACGGACGTACTTATGGCGCTATGTCGCTCACCGCAAAAGCTGCCTATGTGGATGGTTTTGAG
CCTCTTGTGCCAAACGTTGGTATGGTTACCTTTAATGATATTGCGGACTTAGAAGCAAAGGTGTCGGGCAATACCGCCGC
CGTTTTTATTGAGATTGTGCAGGGCGAAGGTGGCATTCATAAAATTTCACAAGAGTTTGTTGATCGCTTAAAAGAGCTAC
GTGAGCAGTTCAACTTTCTTATTGTGGTTGATGATATTCAAGCAGGTTGTGGACGTACAGGTAGCTTTTTTAGCCACACA
ATGGTTAATGCTGAACCTGATCTTATCTGCCTTGCAAAGCCGCTTGGTGGTGGCTTGCCACTTGCCGCCGTGCTCGGTAG
CGAAAAAATGGCTGGCGTGCTTGGTTATGGCAACCACGGCACAACCTTTGGAGGCAATCCTATAGCATGTGCCGCAGGCG
TAGCAATGATTAATGCGATTGTAGAAGATAAGCTAATGGAAAATGCTACAACCGTTGGGCGTTACATTCGTGAAGGGTTT
GAGCAGCTCGCTAAAAAGCATCCGCAAATTCTTGATATTCGCCAATATGGCTTAATGATTGGGGTTACCGTTGATAAAGA
GGCAAAGCCCTACGTTATGAAAGCGCTGGAAAAAGGTGTGCTGGTAAATGCCACAAGCGTTAATGTGATTCGCTTGTTGC
CACCGCTTACCATTACTTGCGAAGAGGCGCAACGCTGCCTTACGGTGCTTGATGAAATTTTTAGTGCTGAAAAGTAA

Upstream 100 bases:

>100_bases
GGAGCTTCCACAGTACATCAGCCAATACAACCACCCGCCGCTTAGGTGGTAGTAGCTCGCTTGTTCAACCATTCCATTAT
TCAAACGCATCAAAAGAACC

Downstream 100 bases:

>100_bases
TGGCACCCAAGCAAGCGAAAAGTGAAGAAAGCGCCATGCCGCTCTCCACCATCAATTATATAATGATTGCTTGTGGAGTT
GTGGTAATTGCTGCAACCTA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNPLPVTQETEQQLFFHNYARLPLAITHGEGVWLVSADGTRYLDMISGIGVNALGYGDRRLVEAISAQASKLIHASNLFL
LQPQFELAEKLLALSGMSKVFFANSGTEAVEAAIKIARKWAGQLGKPNKKEVLSLSNCFHGRTYGAMSLTAKAAYVDGFE
PLVPNVGMVTFNDIADLEAKVSGNTAAVFIEIVQGEGGIHKISQEFVDRLKELREQFNFLIVVDDIQAGCGRTGSFFSHT
MVNAEPDLICLAKPLGGGLPLAAVLGSEKMAGVLGYGNHGTTFGGNPIACAAGVAMINAIVEDKLMENATTVGRYIREGF
EQLAKKHPQILDIRQYGLMIGVTVDKEAKPYVMKALEKGVLVNATSVNVIRLLPPLTITCEEAQRCLTVLDEIFSAEK

Sequences:

>Translated_398_residues
MNPLPVTQETEQQLFFHNYARLPLAITHGEGVWLVSADGTRYLDMISGIGVNALGYGDRRLVEAISAQASKLIHASNLFL
LQPQFELAEKLLALSGMSKVFFANSGTEAVEAAIKIARKWAGQLGKPNKKEVLSLSNCFHGRTYGAMSLTAKAAYVDGFE
PLVPNVGMVTFNDIADLEAKVSGNTAAVFIEIVQGEGGIHKISQEFVDRLKELREQFNFLIVVDDIQAGCGRTGSFFSHT
MVNAEPDLICLAKPLGGGLPLAAVLGSEKMAGVLGYGNHGTTFGGNPIACAAGVAMINAIVEDKLMENATTVGRYIREGF
EQLAKKHPQILDIRQYGLMIGVTVDKEAKPYVMKALEKGVLVNATSVNVIRLLPPLTITCEEAQRCLTVLDEIFSAEK
>Mature_398_residues
MNPLPVTQETEQQLFFHNYARLPLAITHGEGVWLVSADGTRYLDMISGIGVNALGYGDRRLVEAISAQASKLIHASNLFL
LQPQFELAEKLLALSGMSKVFFANSGTEAVEAAIKIARKWAGQLGKPNKKEVLSLSNCFHGRTYGAMSLTAKAAYVDGFE
PLVPNVGMVTFNDIADLEAKVSGNTAAVFIEIVQGEGGIHKISQEFVDRLKELREQFNFLIVVDDIQAGCGRTGSFFSHT
MVNAEPDLICLAKPLGGGLPLAAVLGSEKMAGVLGYGNHGTTFGGNPIACAAGVAMINAIVEDKLMENATTVGRYIREGF
EQLAKKHPQILDIRQYGLMIGVTVDKEAKPYVMKALEKGVLVNATSVNVIRLLPPLTITCEEAQRCLTVLDEIFSAEK

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=30.8673469387755, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=31.3131313131313, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI13994255, Length=421, Percent_Identity=29.4536817102138, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.9620853080569, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=28.1990521327014, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=24.822695035461, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226442709, Length=371, Percent_Identity=28.8409703504043, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI188536080, Length=455, Percent_Identity=24.1758241758242, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679950, Length=455, Percent_Identity=24.1758241758242, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679946, Length=455, Percent_Identity=24.1758241758242, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788044, Length=382, Percent_Identity=35.6020942408377, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789759, Length=377, Percent_Identity=33.6870026525199, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI145693181, Length=373, Percent_Identity=36.1930294906166, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=31.328320802005, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=32.75, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=30.188679245283, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=26.5671641791045, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=394, Percent_Identity=30.9644670050761, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=30.1401869158879, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=272, Percent_Identity=30.5147058823529, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=438, Percent_Identity=26.2557077625571, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71981843, Length=174, Percent_Identity=31.6091954022989, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=430, Percent_Identity=24.6511627906977, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=373, Percent_Identity=34.3163538873995, Blast_Score=229, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6323470, Length=417, Percent_Identity=32.1342925659472, Blast_Score=196, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=463, Percent_Identity=25.4859611231102, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=415, Percent_Identity=25.7831325301205, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=32.2834645669291, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=32.0185614849188, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=32.3185011709602, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21356575, Length=433, Percent_Identity=28.6374133949192, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281366494, Length=442, Percent_Identity=24.6606334841629, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667139, Length=442, Percent_Identity=24.6606334841629, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667143, Length=442, Percent_Identity=24.6606334841629, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42943; Mature: 42943

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLPVTQETEQQLFFHNYARLPLAITHGEGVWLVSADGTRYLDMISGIGVNALGYGDRR
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHCCCCCEECCCHHH
LVEAISAQASKLIHASNLFLLQPQFELAEKLLALSGMSKVFFANSGTEAVEAAIKIARKW
HHHHHHHHHHHHEEECCEEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AGQLGKPNKKEVLSLSNCFHGRTYGAMSLTAKAAYVDGFEPLVPNVGMVTFNDIADLEAK
HHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEHHHCCCCCHHHCCCCCEEEECCHHCCEEE
VSGNTAAVFIEIVQGEGGIHKISQEFVDRLKELREQFNFLIVVDDIQAGCGRTGSFFSHT
ECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHH
MVNAEPDLICLAKPLGGGLPLAAVLGSEKMAGVLGYGNHGTTFGGNPIACAAGVAMINAI
CCCCCCCEEEEECCCCCCCCHHHHHCCCHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
VEDKLMENATTVGRYIREGFEQLAKKHPQILDIRQYGLMIGVTVDKEAKPYVMKALEKGV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCEEEEEEECCCCCHHHHHHHHCCE
LVNATSVNVIRLLPPLTITCEEAQRCLTVLDEIFSAEK
EEEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPLPVTQETEQQLFFHNYARLPLAITHGEGVWLVSADGTRYLDMISGIGVNALGYGDRR
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHCCCCCEECCCHHH
LVEAISAQASKLIHASNLFLLQPQFELAEKLLALSGMSKVFFANSGTEAVEAAIKIARKW
HHHHHHHHHHHHEEECCEEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AGQLGKPNKKEVLSLSNCFHGRTYGAMSLTAKAAYVDGFEPLVPNVGMVTFNDIADLEAK
HHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEHHHCCCCCHHHCCCCCEEEECCHHCCEEE
VSGNTAAVFIEIVQGEGGIHKISQEFVDRLKELREQFNFLIVVDDIQAGCGRTGSFFSHT
ECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHH
MVNAEPDLICLAKPLGGGLPLAAVLGSEKMAGVLGYGNHGTTFGGNPIACAAGVAMINAI
CCCCCCCEEEEECCCCCCCCHHHHHCCCHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
VEDKLMENATTVGRYIREGFEQLAKKHPQILDIRQYGLMIGVTVDKEAKPYVMKALEKGV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCEEEEEEECCCCCHHHHHHHHCCE
LVNATSVNVIRLLPPLTITCEEAQRCLTVLDEIFSAEK
EEEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]