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The map label for this gene is sugE [H]

Identifier: 78188264

GI number: 78188264

Start: 309615

End: 309938

Strand: Reverse

Name: sugE [H]

Synonym: Cag_0283

Alternate gene names: 78188264

Gene position: 309938-309615 (Counterclockwise)

Preceding gene: 78188265

Following gene: 78188255

Centisome position: 12.05

GC content: 50.93

Gene sequence:

>324_bases
ATGGCGTGGGTATATCTTCTACTTGCAGGGTGCCTTGAATGCGCATGGGCAATTGGCTTAAAATATAGTGCAGGCTTTAC
AAAGCCGCTCCCCTCAGCGTTCACAGCAAGCGCCATGCTTGCAAGCTTTTGGTTACTTTCACTTGCTATGAAAAGCATTC
CCGTAGGCACAGCTTATGCCGTTTGGACGGGCATTGGCGCTACGGGTGTTGCCTTGCTTGGTATGGTGCTTTTTGACGAA
TCGCGCGATGTGGCACGCTTGCTCTGCCTTTTGCTCATTCTTGCTGGTGTGGTAGGCTTGCGCATTTTTTCAGGGGGAGA
GTAA

Upstream 100 bases:

>100_bases
CTGGATGCCGCCACCTTTGCTGATGGCTTAATGATTCAACGAGTACTGCACGCAGGCACCGAGTCGCATCAGCAACGCAA
CTGGGTAAAAATTTAAGCAG

Downstream 100 bases:

>100_bases
AGTACACCTCATTCTCCCCTTCCCTTCGCAGCCTTAAAAAAGAGAATGTTGCTGATAAGCATCACGCTTATTGCTTCCAT
TATTAGAACTTACCGCAATT

Product: SugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MAWVYLLLAGCLECAWAIGLKYSAGFTKPLPSAFTASAMLASFWLLSLAMKSIPVGTAYAVWTGIGATGVALLGMVLFDE
SRDVARLLCLLLILAGVVGLRIFSGGE

Sequences:

>Translated_107_residues
MAWVYLLLAGCLECAWAIGLKYSAGFTKPLPSAFTASAMLASFWLLSLAMKSIPVGTAYAVWTGIGATGVALLGMVLFDE
SRDVARLLCLLLILAGVVGLRIFSGGE
>Mature_106_residues
AWVYLLLAGCLECAWAIGLKYSAGFTKPLPSAFTASAMLASFWLLSLAMKSIPVGTAYAVWTGIGATGVALLGMVLFDES
RDVARLLCLLLILAGVVGLRIFSGGE

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=54.9019607843137, Blast_Score=113, Evalue=3e-27,
Organism=Escherichia coli, GI1786755, Length=85, Percent_Identity=38.8235294117647, Blast_Score=63, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11231; Mature: 11099

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVYLLLAGCLECAWAIGLKYSAGFTKPLPSAFTASAMLASFWLLSLAMKSIPVGTAYA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGIGATGVALLGMVLFDESRDVARLLCLLLILAGVVGLRIFSGGE
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AWVYLLLAGCLECAWAIGLKYSAGFTKPLPSAFTASAMLASFWLLSLAMKSIPVGTAYA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGIGATGVALLGMVLFDESRDVARLLCLLLILAGVVGLRIFSGGE
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]