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The map label for this gene is 78188204

Identifier: 78188204

GI number: 78188204

Start: 250060

End: 251286

Strand: Reverse

Name: 78188204

Synonym: Cag_0221

Alternate gene names: NA

Gene position: 251286-250060 (Counterclockwise)

Preceding gene: 78188208

Following gene: 78188203

Centisome position: 9.77

GC content: 43.68

Gene sequence:

>1227_bases
ATGCGTATTTTAACTTTTACGGGTAAAGGCGGAGTAGGTAAAACCAGTGTTTCAGCCGCAACGGCTGTCCGATTATCACA
ACTTGGCTACAGAACCCTCGTGCTTTCCACTGACCCTGCCCACAGCTTATCAGACTCTTACAATCTCCCGCTTGGCGCTG
AACCAACCAAAATTAAGGATAACCTCGATGCCATTGAGGTAAATCCTTACGTTGACCTCAAGCAAAATTGGCACTCCGTC
CAAAAGTACTACACCAAAGTCTTTATGGCGCAAGGCGTTTCGGGGGTTATGGCTGATGAAATGACCATTTTGCCCGGCAT
GGAAGAACTTTTTTCGCTCTTACGTATTAAGCGTTACAAAACAAGCGGCAAATACGATGTGCTTGTGCTCGATACAGCCC
CTACGGGCGAAACCCTTCGCCTCCTCTCCCTACCCGACACTCTGTCGTGGGGTATGAAAGCTGTAAAAAATGTCAATAAA
TATATTATTCGTCCGCTCAGCAAGCCGCTCTCAAAAATGTCGGATAAAATTGCTGACTTTATTCCCCCAACTGATGCAAT
AGACTCGGTGGATCAAGTTTTTGAGGAACTTGAAGATATCCGCAACATTTTAACTGACACAAAAAAATCCACCGTCCGCT
TGGTGATGAACGCTGAAAAAATGTCTATTAAAGAGACAATGCGTGCCCTCACCTATCTCAATCTTTACGGCTTTAATGTG
GATATGGTGTTAGTAAATCGCTTGCTCGACACCCAAGAAAATAGTGGCTACTTGGAAAACTGGAAAGCTATACAGCAAAA
ATATTTAGGCGAAATTGAAGAAGGCTTTGCTCCGCTTCCTGTTAAAAAGCTGAAAATGTATGATCAGGAAATTGTTGGGC
TAAAATCTCTTGAAGTGTTTGCGCACGACATGTATGGCGAAAGCGACCCATCGGTTACCATGCACGATGAACTGCCCATT
AAATTTGTACGTCGCGAAAATGTGTATGAAGTGCAGCTCAAGCTCATGTTTGTTAATCCCGTTGATATTGATATTTGGGT
TACGGGCGATGAGCTGTTTGTTCAAATTGGTAACCAGCGCAAAATTATTACGTTACCATTAAGCTTAACAGGACTTGAAC
CAGGTGAAGCTATCTTTAAAGACAAATGGCTGCACATTCCATTTGACCTCGACAAGAATAACCATACACGCTCCCAACAA
GAGCAGCAAGCCGCATCACGAAGATAA

Upstream 100 bases:

>100_bases
GGTAACAAAGCAAAAGTTCTAAGCACCTTGCTGACTGCTGCCGAACACCATGGAAAAAGCTCTTATTGTTTTTTTGCATT
TCAAAACAAGGTTCCGGTTC

Downstream 100 bases:

>100_bases
TGCTCGTTATGAGAGCGCTTGCTTAGATAAATATTTATGTTTAACTTTGTCGCAGTTAAATGAATCGTACCTCTTCTCAT
AACAGGGGCAATAATGAATG

Product: anion-transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSYNLPLGAEPTKIKDNLDAIEVNPYVDLKQNWHSV
QKYYTKVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKTSGKYDVLVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIIRPLSKPLSKMSDKIADFIPPTDAIDSVDQVFEELEDIRNILTDTKKSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
DMVLVNRLLDTQENSGYLENWKAIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLKSLEVFAHDMYGESDPSVTMHDELPI
KFVRRENVYEVQLKLMFVNPVDIDIWVTGDELFVQIGNQRKIITLPLSLTGLEPGEAIFKDKWLHIPFDLDKNNHTRSQQ
EQQAASRR

Sequences:

>Translated_408_residues
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSYNLPLGAEPTKIKDNLDAIEVNPYVDLKQNWHSV
QKYYTKVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKTSGKYDVLVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIIRPLSKPLSKMSDKIADFIPPTDAIDSVDQVFEELEDIRNILTDTKKSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
DMVLVNRLLDTQENSGYLENWKAIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLKSLEVFAHDMYGESDPSVTMHDELPI
KFVRRENVYEVQLKLMFVNPVDIDIWVTGDELFVQIGNQRKIITLPLSLTGLEPGEAIFKDKWLHIPFDLDKNNHTRSQQ
EQQAASRR
>Mature_408_residues
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSYNLPLGAEPTKIKDNLDAIEVNPYVDLKQNWHSV
QKYYTKVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKTSGKYDVLVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIIRPLSKPLSKMSDKIADFIPPTDAIDSVDQVFEELEDIRNILTDTKKSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
DMVLVNRLLDTQENSGYLENWKAIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLKSLEVFAHDMYGESDPSVTMHDELPI
KFVRRENVYEVQLKLMFVNPVDIDIWVTGDELFVQIGNQRKIITLPLSLTGLEPGEAIFKDKWLHIPFDLDKNNHTRSQQ
EQQAASRR

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=292, Percent_Identity=28.0821917808219, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17557003, Length=305, Percent_Identity=27.5409836065574, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320103, Length=319, Percent_Identity=29.4670846394984, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24586297, Length=302, Percent_Identity=28.8079470198675, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 46276; Mature: 46276

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSYNLPLGAEPTKIKD
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
NLDAIEVNPYVDLKQNWHSVQKYYTKVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYK
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHC
TSGKYDVLVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIIRPLSKPLSKMSDKIADF
CCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPPTDAIDSVDQVFEELEDIRNILTDTKKSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCH
DMVLVNRLLDTQENSGYLENWKAIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLKSLEVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHH
AHDMYGESDPSVTMHDELPIKFVRRENVYEVQLKLMFVNPVDIDIWVTGDELFVQIGNQR
HHHHCCCCCCCEEEECCCCEEEEECCCEEEEEEEEEEECCCEEEEEEECCEEEEEECCCC
KIITLPLSLTGLEPGEAIFKDKWLHIPFDLDKNNHTRSQQEQQAASRR
EEEEEEEEEECCCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSYNLPLGAEPTKIKD
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
NLDAIEVNPYVDLKQNWHSVQKYYTKVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYK
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHC
TSGKYDVLVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIIRPLSKPLSKMSDKIADF
CCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPPTDAIDSVDQVFEELEDIRNILTDTKKSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCH
DMVLVNRLLDTQENSGYLENWKAIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLKSLEVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHH
AHDMYGESDPSVTMHDELPIKFVRRENVYEVQLKLMFVNPVDIDIWVTGDELFVQIGNQR
HHHHCCCCCCCEEEECCCCEEEEECCCEEEEEEEEEEECCCEEEEEEECCEEEEEECCCC
KIITLPLSLTGLEPGEAIFKDKWLHIPFDLDKNNHTRSQQEQQAASRR
EEEEEEEEEECCCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]