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The map label for this gene is glmS [H]

Identifier: 78067622

GI number: 78067622

Start: 3300577

End: 3301584

Strand: Reverse

Name: glmS [H]

Synonym: Bcep18194_A6153

Alternate gene names: 78067622

Gene position: 3301584-3300577 (Counterclockwise)

Preceding gene: 78067623

Following gene: 78067621

Centisome position: 89.37

GC content: 71.73

Gene sequence:

>1008_bases
ATGCTTAAGGAAGCGCGCGAGTCCGCCCAGGTCGTCGCCGCGCAGATCGCCGACACCACGCGCGTCGAAGCGCTCGCCGG
CCAGTTGCTCGATCACCCGCCGGCCGTCGCGCTGACGGTCGCGCGCGGCAGCTCGGATCACGCCGCGAGCTATTTCGCGA
GCCTGACGATGAGCCGCCTCGGCGTGCCGGTCGCATCGCTGCCGATGTCGGTCGCGACGCTGCAGCAGGCGCCGCTGAAG
GTGCAGGACCAGCTCGCGATCGCCTTCTCCCAGTCGGGCAAGAGCCCCGATCTCGTCAATACGATGGCCGCGCTGCGCGA
AGCCGGCGCGCGCACCGTCGCCGCCGTGAACGTGCTGCCGTCGCCGCTCGCCGACGCATGCGAGCATCAGTTGCCGCTGC
TCGCCGGCCCCGAACTGTCGGTGGCCGCGACCAAGAGCTATATCGCGATGCTGTCGCTGTCCGCGCAGATCGTTGCGTAC
TGGCAGCGCGACGCCGCGCTGATGACCGCGCTGCGCGGCCTGCCCGACGTGCTCGCGCAGGCCGGCCAGCTCGACTGGTC
GCAGGCCGTTGCCGCGCTGGCGGGCGTCGAACGGATGATCGTGATCGGCCGCGGCCTGGGCCTCGCGATCGCGCAGGAAG
CCGCGCTGAAGCTGAAGGAAACGTCCGGCATCCAGGCCGAGGCGTTCTCGAGCGCCGAAGTCCGTCACGGCCCGATGGAG
CTGATCGACCGCGACTATCCGCTGCTCGTGTTCGCGCCGCCGGGGCCCGAGCAGGCCGGCCTGCTGCAGCTCGCCGCAGA
CATGCGCGCCCGCGGCGCCGCCGTGCTGCTCGCGGCACCCGCCGGCACGCCCGGCGCGACGCTGCCGCTTGCGCGGTCCG
CCCATTCGGCGCTCGACCCGATCGCCGCCATTCTTTCGTTCTACGTGATGGCGGCGGATCTCGCCGTCGCGCGCGGCCGC
AATCCCGACACGCCGCGCCACCTGAACAAAGTCACCGAAACGCACTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCCTCGAGCGCGGCGCATGGGCCGACCTCGCGGTGTTCGATCGCGACCTGAACCTCACCGCGACCTATGTCGA
AGGAGAATCGATTGTCGAAT

Downstream 100 bases:

>100_bases
TAGCCGAGACAGCCGATGAGACGCGCCGAGGAGTCCCAGTTGAAGAGCCCCACCCACGATCAGATCGTCCTGCTTGCCCC
GTTGACGGGGCCGATCGTCG

Product: glutamine-fructose-6-phosphate transaminase (isomerizing)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLAIAFSQSGKSPDLVNTMAALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAY
WQRDAALMTALRGLPDVLAQAGQLDWSQAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGATLPLARSAHSALDPIAAILSFYVMAADLAVARGR
NPDTPRHLNKVTETH

Sequences:

>Translated_335_residues
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLAIAFSQSGKSPDLVNTMAALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAY
WQRDAALMTALRGLPDVLAQAGQLDWSQAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGATLPLARSAHSALDPIAAILSFYVMAADLAVARGR
NPDTPRHLNKVTETH
>Mature_335_residues
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLAIAFSQSGKSPDLVNTMAALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAY
WQRDAALMTALRGLPDVLAQAGQLDWSQAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGATLPLARSAHSALDPIAAILSFYVMAADLAVARGR
NPDTPRHLNKVTETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=356, Percent_Identity=26.123595505618, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI205277386, Length=324, Percent_Identity=25.6172839506173, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1790167, Length=322, Percent_Identity=30.1242236024845, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17532897, Length=309, Percent_Identity=25.2427184466019, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17532899, Length=309, Percent_Identity=25.2427184466019, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17539970, Length=333, Percent_Identity=25.2252252252252, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322745, Length=309, Percent_Identity=25.5663430420712, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357745, Length=354, Percent_Identity=23.4463276836158, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 34768; Mature: 34768

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQDQLAIAFSQSGKSPDLVNTMAALREAGARTVAAVNVLP
CCCHHHHCHHHHHHHHCCCCHHHHEEEEECCCCCCCHHHHHHHHHHHCCCHHEEEECCCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAYWQRDAALMTALRGLPDVLAQ
CHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AGQLDWSQAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGATLPLARSAHSALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
IAAILSFYVMAADLAVARGRNPDTPRHLNKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQDQLAIAFSQSGKSPDLVNTMAALREAGARTVAAVNVLP
CCCHHHHCHHHHHHHHCCCCHHHHEEEEECCCCCCCHHHHHHHHHHHCCCHHEEEECCCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAYWQRDAALMTALRGLPDVLAQ
CHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AGQLDWSQAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGATLPLARSAHSALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
IAAILSFYVMAADLAVARGRNPDTPRHLNKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA