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The map label for this gene is hisC2

Identifier: 78067604

GI number: 78067604

Start: 3278844

End: 3279911

Strand: Direct

Name: hisC2

Synonym: Bcep18194_A6135

Alternate gene names: 78067604

Gene position: 3278844-3279911 (Clockwise)

Preceding gene: 78067603

Following gene: 78067608

Centisome position: 88.76

GC content: 67.04

Gene sequence:

>1068_bases
GTGAGCCGTTACTGGAGCGACATCGTTCAGCAACTCGTGCCTTACGTGCCGGGCGAGCAGCCCGCGCTCGCACACCCCGT
CAAGCTGAACACCAACGAGAATCCCTATCCGCCGTCACCGCGCGTCGTCGCGGCGATCGCGCGCGAACTCGGCGAGACCG
GCGACACGCTGCGCCGCTATCCCGACCCGGTCGCGCGCGCGCTGCGCGAGACGGTCGCGACCCATCACCGCATCAAGCCC
GAGCAGGTGTTCGTCGGCAACGGCTCCGACGAGGTGCTCGCGCACACGTTCCAGGCGCTGCTCAAGCACGACCGGCCGCT
GCGCTTCCCCGACATCACCTACAGCTTCTATCCCACCTATGCGCGCCTGTACGGCGTCCAGACGTCGAACGTGCCGCTCG
CGGACGATTTCTCGATCCGCGTGGACGACTATCTCGACGACGCCGGCGGCGTGCTGTTTCCGAACCCGAACGCGCCGACC
GGGCGCGCACTGCCGCTCGCGGACGTCGAGCGGATCGTGGCCGCGAATCCGTCGTCGGTCGTCGTGATCGATGAAGCCTA
CGTCGACTTCGGCGCGCAGTCCGCGATTACGCTGATCGACCGCTACCCGAACCTGCTCGTCGTGCACACGACGTCGAAGG
CGCGCTCGCTCGCGGGCATGCGCGTCGGCTTCGCGTTCGGCGAAGCAGCGCTGATCGACGCGCTGAACCGCGTGAAGGAC
AGCTTCAATTCGTACCCGCTCGACCGGCTCGCGCAGGTCGCCGCGCAGGCTGCGTACGAAGACACCGATTATTTCAACGC
AACCTGCCGGCGCGTGATCGACAGCCGGACACGTCTCACGCATGCGCTCGACGCGCTCGACTTCAACATCGTGCCGTCGG
CCGCGAATTTCGTGTTCGCGCGCCATCCCGCGCACGACGCAGGTGCGATTGCGGCAAAACTGAAGGAACGGGAAATTTTC
GTGCGGCACTTCCGGCTGCCGCGGATCGACCAGCACCTGCGCATCACCGTCGGCACCGACGCCGAATGCGATGCGCTCGT
CGCGGCGTTGCGCGAGCTGCTGGCCTGA

Upstream 100 bases:

>100_bases
CCGGCGCATCGAGCCGTCCGGCGCCGCCGGGCGGCCCCGCCGGCCCCTCCCTGCGCGCACATGCGGTAATCTGGTCGCTT
TGCCCGACAGGAGCCAAGCG

Downstream 100 bases:

>100_bases
AATGAACGAACCGGCGCCAGGCGGCGCCGGTCCGGATGCGTGACGTGCGTGCCGAAGAACCCGGGCACGCGCGCCACCGC
GGGGTCACGACGCGTCGTCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSRYWSDIVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRYPDPVARALRETVATHHRIKP
EQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTYARLYGVQTSNVPLADDFSIRVDDYLDDAGGVLFPNPNAPT
GRALPLADVERIVAANPSSVVVIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGEAALIDALNRVKD
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRTRLTHALDALDFNIVPSAANFVFARHPAHDAGAIAAKLKEREIF
VRHFRLPRIDQHLRITVGTDAECDALVAALRELLA

Sequences:

>Translated_355_residues
MSRYWSDIVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRYPDPVARALRETVATHHRIKP
EQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTYARLYGVQTSNVPLADDFSIRVDDYLDDAGGVLFPNPNAPT
GRALPLADVERIVAANPSSVVVIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGEAALIDALNRVKD
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRTRLTHALDALDFNIVPSAANFVFARHPAHDAGAIAAKLKEREIF
VRHFRLPRIDQHLRITVGTDAECDALVAALRELLA
>Mature_354_residues
SRYWSDIVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRYPDPVARALRETVATHHRIKPE
QVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTYARLYGVQTSNVPLADDFSIRVDDYLDDAGGVLFPNPNAPTG
RALPLADVERIVAANPSSVVVIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGEAALIDALNRVKDS
FNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRTRLTHALDALDFNIVPSAANFVFARHPAHDAGAIAAKLKEREIFV
RHFRLPRIDQHLRITVGTDAECDALVAALRELLA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily

Homologues:

Organism=Escherichia coli, GI1788332, Length=355, Percent_Identity=31.2676056338028, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788722, Length=242, Percent_Identity=29.3388429752066, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=364, Percent_Identity=29.6703296703297, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS82_BURS3 (Q39CT7)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_370373.1
- ProteinModelPortal:   Q39CT7
- STRING:   Q39CT7
- GeneID:   3751368
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A6135
- NMPDR:   fig|269483.3.peg.7616
- eggNOG:   COG0079
- HOGENOM:   HBG646350
- OMA:   MQAELND
- ProtClustDB:   PRK05387
- BioCyc:   BSP36773:BCEP18194_A6135-MONOMER
- HAMAP:   MF_01023
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR01141

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.9

Molecular weight: Translated: 39282; Mature: 39151

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYWSDIVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRY
CCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHC
PDPVARALRETVATHHRIKPEQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHH
ARLYGVQTSNVPLADDFSIRVDDYLDDAGGVLFPNPNAPTGRALPLADVERIVAANPSSV
HHHEECCCCCCCCCCCCEEEEHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCE
VVIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGEAALIDALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRTRLTHALDALDFNIVPSAANFVFA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEE
RHPAHDAGAIAAKLKEREIFVRHFRLPRIDQHLRITVGTDAECDALVAALRELLA
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SRYWSDIVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRY
CHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHC
PDPVARALRETVATHHRIKPEQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHH
ARLYGVQTSNVPLADDFSIRVDDYLDDAGGVLFPNPNAPTGRALPLADVERIVAANPSSV
HHHEECCCCCCCCCCCCEEEEHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCE
VVIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGEAALIDALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRTRLTHALDALDFNIVPSAANFVFA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEE
RHPAHDAGAIAAKLKEREIFVRHFRLPRIDQHLRITVGTDAECDALVAALRELLA
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA