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The map label for this gene is pdhR [H]

Identifier: 78067549

GI number: 78067549

Start: 3222474

End: 3223190

Strand: Reverse

Name: pdhR [H]

Synonym: Bcep18194_A6080

Alternate gene names: 78067549

Gene position: 3223190-3222474 (Counterclockwise)

Preceding gene: 78067554

Following gene: 78067548

Centisome position: 87.25

GC content: 70.01

Gene sequence:

>717_bases
ATGGCAGCGATGACGGCACGGGGCCGGACCGAAGTGGTGATGCGCAAGATCGAGACGGCGCTGCTCGACGGCACCTGGCC
GGCCGGCGCGCGTCTGCCGGCCGAGCGCGTGCTCGCGCAGGAATACGGCGTCGCGCGCAATACGGTGCGCGAGGCGACCC
AGCGGCTCGTCGCGCGCGGGCTGCTGCAGAGCCGGCGCGGCGCGGGCGTCTACGTGACCGACCAGTTGCGTGCCGGTATC
GCGTCACCGTGGGGCCAGCTGGTTGCCGATCATCCGGCGCTGCGCGACGACATCCTCGAGTTCCGCCGCGTGCTCGAAGG
CGCGACCGCCTATTTCGCCGCGCTGCGCGCCGATACGAACGACCGGCGCCGGATCCGTACGCTGCTGCGCGAGCTCGAAA
CCGCGCACGCGAACGGCGCCGCGGCCGTCGAAGCCGCGACCGACGCGAAGCTGCACGAGGCGATCGCGCTCGCGTCGCAC
AACACGATGTTCCTGCACCTGCATACGAGCGTGATCGGGATGCTGCGCGAACACATCTCGATCAACGTGGCGGGCATGAC
GACGCACGACGAGCAGGCGTCCGAGCTGCTGTTGCTGCAGCACCGCGTCGTGTGCGAAGCCATCTGCGCACAACGTCCCG
AAGAGGCGCGCACCGCGATGCAGACGCACATCGACTACGTGCGCAGCCATTTCGAGCGCAGCGGCGACGGAGCCTGA

Upstream 100 bases:

>100_bases
TGCGGGACGACGATTTCGCTGCATAATTCCCGCGACGGCGCCGTAGCTCAAATTGGTTGGGCCAATCGGCGCGGCACGCA
TTCCGCAGGGAGACGCGACG

Downstream 100 bases:

>100_bases
GATTGGTCGGACCGCTTCGACGCGTGGCCCGTGCGGCGGGCACCTCCGGTGCGGCGAGGCATCGATGCCCGGCAGGCGGG
TTCCCGTCCGCGGTCCGAAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAAMTARGRTEVVMRKIETALLDGTWPAGARLPAERVLAQEYGVARNTVREATQRLVARGLLQSRRGAGVYVTDQLRAGI
ASPWGQLVADHPALRDDILEFRRVLEGATAYFAALRADTNDRRRIRTLLRELETAHANGAAAVEAATDAKLHEAIALASH
NTMFLHLHTSVIGMLREHISINVAGMTTHDEQASELLLLQHRVVCEAICAQRPEEARTAMQTHIDYVRSHFERSGDGA

Sequences:

>Translated_238_residues
MAAMTARGRTEVVMRKIETALLDGTWPAGARLPAERVLAQEYGVARNTVREATQRLVARGLLQSRRGAGVYVTDQLRAGI
ASPWGQLVADHPALRDDILEFRRVLEGATAYFAALRADTNDRRRIRTLLRELETAHANGAAAVEAATDAKLHEAIALASH
NTMFLHLHTSVIGMLREHISINVAGMTTHDEQASELLLLQHRVVCEAICAQRPEEARTAMQTHIDYVRSHFERSGDGA
>Mature_237_residues
AAMTARGRTEVVMRKIETALLDGTWPAGARLPAERVLAQEYGVARNTVREATQRLVARGLLQSRRGAGVYVTDQLRAGIA
SPWGQLVADHPALRDDILEFRRVLEGATAYFAALRADTNDRRRIRTLLRELETAHANGAAAVEAATDAKLHEAIALASHN
TMFLHLHTSVIGMLREHISINVAGMTTHDEQASELLLLQHRVVCEAICAQRPEEARTAMQTHIDYVRSHFERSGDGA

Specific function: Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786303, Length=219, Percent_Identity=36.986301369863, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790032, Length=219, Percent_Identity=34.703196347032, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790780, Length=230, Percent_Identity=30, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789353, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994955, Length=227, Percent_Identity=26.431718061674, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082208, Length=216, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26229; Mature: 26098

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAMTARGRTEVVMRKIETALLDGTWPAGARLPAERVLAQEYGVARNTVREATQRLVARG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQSRRGAGVYVTDQLRAGIASPWGQLVADHPALRDDILEFRRVLEGATAYFAALRADTN
HHHHCCCCCEEEEHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DRRRIRTLLRELETAHANGAAAVEAATDAKLHEAIALASHNTMFLHLHTSVIGMLREHIS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHE
INVAGMTTHDEQASELLLLQHRVVCEAICAQRPEEARTAMQTHIDYVRSHFERSGDGA
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAMTARGRTEVVMRKIETALLDGTWPAGARLPAERVLAQEYGVARNTVREATQRLVARG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQSRRGAGVYVTDQLRAGIASPWGQLVADHPALRDDILEFRRVLEGATAYFAALRADTN
HHHHCCCCCEEEEHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DRRRIRTLLRELETAHANGAAAVEAATDAKLHEAIALASHNTMFLHLHTSVIGMLREHIS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHE
INVAGMTTHDEQASELLLLQHRVVCEAICAQRPEEARTAMQTHIDYVRSHFERSGDGA
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]