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The map label for this gene is pcpR [H]

Identifier: 78067205

GI number: 78067205

Start: 2840562

End: 2841488

Strand: Direct

Name: pcpR [H]

Synonym: Bcep18194_A5736

Alternate gene names: 78067205

Gene position: 2840562-2841488 (Clockwise)

Preceding gene: 78067203

Following gene: 78067206

Centisome position: 76.89

GC content: 69.69

Gene sequence:

>927_bases
ATGATGCATCCCGATCTACGCCGCCTCGACCTGAACCTGCTGCTCGTGTTCGATGCGCTGTACCGTCACCGCTCCGTCGC
CGCGGCCGCACACGAGCTCGCGTTGAGCCCGTCCGCGTTGAGCCACGCGCTCGCGCGGCTGCGCGACGCGATCGGCGACG
CACTGTTCGTGCGCCTCGGCAACGAGATGCAGCCGACCGTGCGCGCCGACGACATCGCGACCTGGGCCGGCGATGCGCTC
GACACGATGTCGAAGGGGCTCGCCCGCGCGCGCCGCTTCGATCCCGCGCAAAGCGACCGCACGTTCGTGTTCGCGGCGAC
CGACTACACGGCCTTCGCCGTATTGCCGGCGTTTCTCGCACGCATCCAGCATGTGGCGCCGCGACTGCGGATCCGCGTCG
TGCATTCCGACCGGAAAATCTCCGTCGACGAACTCGCGGCCGGCCGCATCGATTTCGCGCTCGGCTATCACGAGGAATCG
GCGGCCGACGCGCCGGGCATCGAGGACTTCGACTGGTTCTCCGACGACTACGTCGTGATCGCGAGCGCCACGCATCCGGA
CATCCGCCGGCGGCTGACGCTCGACCAGTACCTGGCGGCACGCCACGTGGTCGTCACGCCGTGGAACGAGTCGCGCGGCG
TCGTCGACCATGTGCTCGACCGGCTCGGCCTCGCGCGGCAGGTCGCCGTGCAGTTGCCGACCGTGCTGGCCGCGCCGTTC
GTGATCGCGGAATCCGCGCTGCTGATGACCGTGCCGAACCGCGCCGCGCAGGCGCTGCGGCACGCGGCGCCGATCCGCAT
CTTTCCCGCGCCGTTCGAGATCCCGCGCTACACCGTGAAGGTCTACTCGCACGCGAAGCATGCGCGCACCGATGCGCATC
GCTGGATTCGCGCGCAGTTGCTCGAGGCCAGGCCCGCCACACCCTGA

Upstream 100 bases:

>100_bases
GGGAAACGGCGCCGCGCAGCCGCGCTGGCGCCCATCAGATCGTCATGCTACGTTCACGCAGCGCCTGCAGGAAGTGCAGT
TTCTTCATCCGGACCTGAAC

Downstream 100 bases:

>100_bases
CCAACGCACGTCGGAACATCGCGCTGCGCGTTGCCGGACAAGGGTTTCAGGCAGCGGCTGGCCCTCTCCGGCAGCCGCTC
ATTCATTACGAAATACTTAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDAL
DTMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLARIQHVAPRLRIRVVHSDRKISVDELAAGRIDFALGYHEES
AADAPGIEDFDWFSDDYVVIASATHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDHVLDRLGLARQVAVQLPTVLAAPF
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLEARPATP

Sequences:

>Translated_308_residues
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDAL
DTMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLARIQHVAPRLRIRVVHSDRKISVDELAAGRIDFALGYHEES
AADAPGIEDFDWFSDDYVVIASATHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDHVLDRLGLARQVAVQLPTVLAAPF
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLEARPATP
>Mature_308_residues
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDAL
DTMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLARIQHVAPRLRIRVVHSDRKISVDELAAGRIDFALGYHEES
AADAPGIEDFDWFSDDYVVIASATHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDHVLDRLGLARQVAVQLPTVLAAPF
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLEARPATP

Specific function: Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation. Essential for PCP degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=26.0586319218241, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87081766, Length=271, Percent_Identity=25.830258302583, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790147, Length=271, Percent_Identity=27.6752767527675, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786820, Length=62, Percent_Identity=46.7741935483871, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34285; Mature: 34285

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHCC
NEMQPTVRADDIATWAGDALDTMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLA
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHH
RIQHVAPRLRIRVVHSDRKISVDELAAGRIDFALGYHEESAADAPGIEDFDWFSDDYVVI
HHHHHCCCEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
ASATHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDHVLDRLGLARQVAVQLPTVLAAPF
EECCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQL
HHHCCEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LEARPATP
HHCCCCCC
>Mature Secondary Structure
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHCC
NEMQPTVRADDIATWAGDALDTMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLA
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHH
RIQHVAPRLRIRVVHSDRKISVDELAAGRIDFALGYHEESAADAPGIEDFDWFSDDYVVI
HHHHHCCCEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
ASATHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDHVLDRLGLARQVAVQLPTVLAAPF
EECCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQL
HHHCCEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LEARPATP
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12169590 [H]