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The map label for this gene is lysN [H]

Identifier: 78067159

GI number: 78067159

Start: 2796432

End: 2797613

Strand: Direct

Name: lysN [H]

Synonym: Bcep18194_A5690

Alternate gene names: 78067159

Gene position: 2796432-2797613 (Clockwise)

Preceding gene: 78067158

Following gene: 78067160

Centisome position: 75.7

GC content: 68.87

Gene sequence:

>1182_bases
ATGAATCCGAGCGACCTGCATCCGCCGCACTGGCAGCTTTCCGAACGCGCACGCAAGCTGACGAGCTCTGCAATCCGCGA
AATCCTGAAGGTCACGGAACGCCCCGAGGTCATCTCGTTCGCCGGCGGCCTGCCCGCCCCTGCCACGTTCCCGGCCGAGC
GCATGCGCGCCGCCGCCGATCGCGTGCTGCGCGACGCGCCGGCCGCCGCGCTCCAGTACAGCGCGACCGAAGGCTACCTG
CCGCTGCGCGAATGGATCGCCGAGCGCTACAGCGTGCGCGTGTCGCAGGTGCTGATCACGACCGGCTCGCAGCAGGCGCT
CGACCTGCTCGGCAAGGCGCTCGTCGATCCGGGCAGCCCGATCCTCGTCGAAACCCCCACCTACCTCGGCGCGCTGCAGT
CGTTCTCGCTGTACGAGCCGCGCTACGTGCAGGTGCCGACCGACGAGCAGGGCCTGCTGCCGGACGGCCTCACGCCCGAA
CTCACGCAAGGCGCGCGCCTGCTGTACGCGCAGCCGAACTTCCAGAACCCGACCGGCCGCCGCCTGCCCGTCGAGCGCCG
CCGCGCGCTCGCCGCGTTCGCGCAATCGAGCCCGTTCCCGGTGCTGGAAGACGATCCGTACGGCGCGCTGAACTACCGCG
GCGAGCCGCTGCCGACGATGCTGTCGATGGCGCCCGATCACATCGTGCACCTCGGCACGTTCTCGAAGGTGCTCGCACCG
GGCCTGCGGATCGGCTACATCATTGCCCCCGAAGAACTCCACTTCAAGCTCGTACAGGCCAAGCAGGCCACCGACCTGCA
CACGCCGACGCTCACGCAGCGCATCGCGCACGAAGTGATCAAGGACGGCTTCCTCGACGAGCACATCCCGACGATCCGCG
AGCTGTACAGCGCGCAATGCGACGCGATGCTCGCCGCGCTCGAGCGCCACATGCCGGAAGGCATCACGTGGAACCGCCCG
GAAGGCGGGATGTTCATCTGGGTGAACCTGCCCGCGCAGATCGACAGCATGAAGCTGCTCGCCACGGCCGTCGACAACCA
CGTCGCCTTCGTGCCGGGCGCGCCGTTCTTCGCGGACAACGCGCAACAGAACACGCTGCGCCTGTCGTTCGTGACGGTGC
CGCCCGAGAAGATCGAGGAAGGCGTCGCGCGCCTCGGCAAGCTGCTGCGCGAGCGTCTCTGA

Upstream 100 bases:

>100_bases
CGAAGGCTCGATCGCGCTCGTGCCTGCCCACCCGGCAGCGTCGAAGCGATTTGCCCGAACGACCTTTCTTGACTGACCAC
GATATCCGAACGAGGAGACT

Downstream 100 bases:

>100_bases
TCCCCTTTTTCCTGTCACGACTCTCTACGAGGAATCGAATACATGGCTAACGTCTACGACAAACTCAAGTCGCTCGGCAT
CGAGCTCCCGACCGCCGGCG

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALVDPGSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPDGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQSSPFPVLEDDPYGALNYRGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQCDAMLAALERHMPEGITWNRP
EGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADNAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Sequences:

>Translated_393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALVDPGSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPDGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQSSPFPVLEDDPYGALNYRGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQCDAMLAALERHMPEGITWNRP
EGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADNAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
>Mature_393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALVDPGSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPDGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQSSPFPVLEDDPYGALNYRGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQCDAMLAALERHMPEGITWNRP
EGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADNAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=410, Percent_Identity=30.4878048780488, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI33469970, Length=410, Percent_Identity=30.4878048780488, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=28.0839895013123, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790797, Length=336, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788722, Length=343, Percent_Identity=25.6559766763848, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994949, Length=227, Percent_Identity=27.3127753303965, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=485, Percent_Identity=23.9175257731959, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321000, Length=264, Percent_Identity=28.7878787878788, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321929, Length=489, Percent_Identity=23.3128834355828, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356535, Length=392, Percent_Identity=26.530612244898, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43521; Mature: 43521

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYSVRVSQVLITTGSQQALDLLGKALVDPGSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPDGLTPELTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQSSPFPVLEDDPYGALNYRGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAMLAALERHMPEGITWNRPEGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADN
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYSVRVSQVLITTGSQQALDLLGKALVDPGSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPDGLTPELTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQSSPFPVLEDDPYGALNYRGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRELYSAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAMLAALERHMPEGITWNRPEGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADN
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA