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The map label for this gene is alsR [H]

Identifier: 78066939

GI number: 78066939

Start: 2554269

End: 2555171

Strand: Direct

Name: alsR [H]

Synonym: Bcep18194_A5470

Alternate gene names: 78066939

Gene position: 2554269-2555171 (Clockwise)

Preceding gene: 78066935

Following gene: 78066940

Centisome position: 69.14

GC content: 68.0

Gene sequence:

>903_bases
ATGGAACTGAGGCAGTTGCGCTACTTCGTGGCGGTCGCCGAGGAGCTGCATTTCGGGCGCGCGGCGAAGCGCCTGTTCAT
CTCGCAGCCGGCGCTGAGTTTCGACATCCGCAAGTTCGAGGACGCGCTTGGCGTGCAGCTGTTCTCGCGCACCAACAAGA
CCGTCGCACTGACCAACGCGGGCGAGGTGCTGCTCGGCGAAGCGCGCCGGCTGCTGCTGCAGGCGGCCGAGGCCGAACGC
CTGACGGTGCGCTCCGCCTCCGGTCTCGCGGGCCGGCTGCGGATCGGCTTCGTTCATTCGATGCTGTATCGCGGGCTGCC
CGATGCCGTGCGGCGCTTCGAGGCCGACTACCCCGGTGTCGAAGTCGTGCTGAGCGAAATGAACACGCAGGCGCAGGTAC
AGGCGATCCAGCGCGGCCAGATCGATCTCGGCTATGCGCACTGGGGCCACTTCCCGCCCGAAGTCGAATCGACGCCCGTC
TATGCGGAGCCGTTCGTGTGCTGCCTGCCGGCCGCGCATCCGCTCGCGAAGCGCAAGCAGGTCGCGCTCGCCGCGCTGGC
CTCGGAGCCGTTCATCCTGTTTCCGCGCGAAGCGGCGCCCCACTATCACGACCTGATCATCGCGCAGTGCGTGAATGCCG
GCTTCAGCCCGCTGATCCGCCACGAGGCACGGCTGTGGCAGACGATCCTGTCGATGATCGAGTTCGGGATGGGTATCGCG
CTCGTGCCGCGCGTGCTGCAGCAGGTGAAGAGCGAGCGGCTCGCGTTCCGGTCGCTGAAGGATGCGTCGCTCGAATCGCG
CACGCTCGCGCTGAAGCGCAGCGGCACCACTGAGCCCGTGGCGCTGCGCTTCGCGGATTACGTCCGCGCGTCGATCGACG
CACTGCCCGCGCTGGCAGGCTGA

Upstream 100 bases:

>100_bases
CTTCCGCAGAGCGTAGGCGCGCGATCGATAAGCGTCCAATACAGGATTTATCCGGTACGATAGATATCGCTTATCGATGC
CGACGCCGCGAGGAGACACG

Downstream 100 bases:

>100_bases
GCTGGCCGACGGCCAATGGGTCTTGCGCGGGGGCGTGAAAAAAATTGCAGAAAGGGCTTTACAGACCCCAAAAGCTCTGA
CATAATCTTTTCTTCTTTGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEDALGVQLFSRTNKTVALTNAGEVLLGEARRLLLQAAEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGVEVVLSEMNTQAQVQAIQRGQIDLGYAHWGHFPPEVESTPV
YAEPFVCCLPAAHPLAKRKQVALAALASEPFILFPREAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
LVPRVLQQVKSERLAFRSLKDASLESRTLALKRSGTTEPVALRFADYVRASIDALPALAG

Sequences:

>Translated_300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEDALGVQLFSRTNKTVALTNAGEVLLGEARRLLLQAAEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGVEVVLSEMNTQAQVQAIQRGQIDLGYAHWGHFPPEVESTPV
YAEPFVCCLPAAHPLAKRKQVALAALASEPFILFPREAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
LVPRVLQQVKSERLAFRSLKDASLESRTLALKRSGTTEPVALRFADYVRASIDALPALAG
>Mature_300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEDALGVQLFSRTNKTVALTNAGEVLLGEARRLLLQAAEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGVEVVLSEMNTQAQVQAIQRGQIDLGYAHWGHFPPEVESTPV
YAEPFVCCLPAAHPLAKRKQVALAALASEPFILFPREAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
LVPRVLQQVKSERLAFRSLKDASLESRTLALKRSGTTEPVALRFADYVRASIDALPALAG

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=39.0438247011952, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=37.4045801526718, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=34.1296928327645, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI157672245, Length=302, Percent_Identity=31.1258278145695, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=30.8641975308642, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI145693105, Length=243, Percent_Identity=31.6872427983539, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790208, Length=284, Percent_Identity=28.8732394366197, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=28.6307053941909, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787530, Length=246, Percent_Identity=26.4227642276423, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788296, Length=299, Percent_Identity=26.4214046822742, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=28.8461538461538, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=196, Percent_Identity=32.6530612244898, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787601, Length=159, Percent_Identity=32.7044025157233, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081904, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=153, Percent_Identity=32.0261437908497, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=25, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790262, Length=299, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994962, Length=81, Percent_Identity=45.679012345679, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=248, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33256; Mature: 33256

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEDALGVQLFSRTNKTVALTNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GEVLLGEARRLLLQAAEAERLTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGV
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
EVVLSEMNTQAQVQAIQRGQIDLGYAHWGHFPPEVESTPVYAEPFVCCLPAAHPLAKRKQ
HHHHHHHCHHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHH
VALAALASEPFILFPREAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LVPRVLQQVKSERLAFRSLKDASLESRTLALKRSGTTEPVALRFADYVRASIDALPALAG
HHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEDALGVQLFSRTNKTVALTNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GEVLLGEARRLLLQAAEAERLTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGV
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
EVVLSEMNTQAQVQAIQRGQIDLGYAHWGHFPPEVESTPVYAEPFVCCLPAAHPLAKRKQ
HHHHHHHCHHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHH
VALAALASEPFILFPREAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LVPRVLQQVKSERLAFRSLKDASLESRTLALKRSGTTEPVALRFADYVRASIDALPALAG
HHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]