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The map label for this gene is argA [H]

Identifier: 78066934

GI number: 78066934

Start: 2547809

End: 2549188

Strand: Direct

Name: argA [H]

Synonym: Bcep18194_A5465

Alternate gene names: 78066934

Gene position: 2547809-2549188 (Clockwise)

Preceding gene: 78066928

Following gene: 78066935

Centisome position: 68.97

GC content: 66.74

Gene sequence:

>1380_bases
ATGAATTCCCAAACCGACCTCCCCCCCGCCCAGACCGGCGCCACGACGCCGCCGGCTGCCGACGACTCGGCCGCCAGTCA
CGCGCAGTTCGTCGACTGGATGCGCTCCGTCGCGCCCTATATCCACAAGTTCCGCAACAGCACGTTCGTCGTGGGGTTTG
GCGGCGAGGTGGTGCAGCAGGGGCTGCTGAATGCGCTCGTGTCCGACATCGCGCTGCTGCAGGCGATGGGTATCCAGATC
GTGCTGGTGCACGGCTCGCGCCCGCAGGTCGAGGAGCAGCTGAGCCTGCATGGTGTCGAATCCGAGTTTTCGCACGGGCT
GCGCATCACCGATGCGCGCGCGCTCGAATCCGCGAAGGAAGCGGCCGGTGAAGTGCGTCTCGACATCGAGGCCGCGATCA
GCCAGGGTCTGCCGAACTCGCCGATGGCGCACGCGCACATCAGCGTCGTGTCGGGCAACTTCGTGACCGCGCGGCCGGTG
GGGATTCTCGACGGGGTCGATTTCGCGCATACGGGCATCGTGCGCAAGATCGACGCCGAATCGATCCGTCATTCGCTCTC
GAGCCGCAAGCTCGTGCTGCTGTCGCCGCTCGGGTTCTCGCCGACCGGCGAAGCGTTCAACCTGTCGATGGAAGACGTGG
CGTCGGCCGCCGCGATCGCGCTGCGCGCCGACAAGATCGTGTTCCTGACCGAAGGCCCCGGCATCGTCGACGACGAAGGC
GAGCTGATCCGCGAAATGTCGCTCGACGCGGCGGCCGAGCTGCTCGATTCCGGCAACGTCCAGGGCGACGACGCGTTCTT
CCTGAAGCATTCGATCCGCGCGTGCCGCGGCGGCGTGACCCGGGCGCACCTGATCCCGCAATCGCTCGACGGCAGCATGC
TGCTCGAACTGTTCCTGCACGACGGCGTCGGCACGATGATCTCGTACGAGAACCTCGAGAGCCTGCGCGAAGCGACGCCG
GACGACGTCGGCGGCATCCTGTCGCTGATCGAGCCGCTCGAGTCGGACGGCACGCTGGTGCGACGCGGCCGCCACCAGAT
CGAACGCGACATCGACCACTTCTCGGTGATCGAGCACGATGGCGTGCTGTTCGGCTGCGCGGCGCTGTATCCGTACCAGC
AGGAAAAGATCGGCGAGATGGCGTGCCTGACGGTCGCGCCGGAAGCGCAGGGCTCGGGCGACGGCGAACGCCTGCTCAAG
CGGATCGAGCAGCGCGCCCGCGCGCGCGGCCTCACGCATATCTTCGTGCTCACGACGCGCACCGAGCACTGGTTCCTCAA
GCGCGGCTTCGTCAAGGTCAGCGTCGACGACCTGCCGGAAGACCGCCGCAAACTCTATAACTGGCAGCGCAAGTCGCTCG
TGCTGATGAAACAGCTCTGA

Upstream 100 bases:

>100_bases
TCGGCCGCACCATCCGGGTGCCGGGCCGACGGCGTATTGGCCCGCGTCGGCGCGGGACTTTTAGAAACATTCGACATGGG
GGCGCATTATAATCCCGCCC

Downstream 100 bases:

>100_bases
GCGCAGGCACGACTGCCCTCCCCCAGACCGATTACAGGAGAAGTACACGATGGCTCGAATGATCCAATGCGCGAAGCTCG
GCAAGGAAGCCGAAGGCCTC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNSQTDLPPAQTGATTPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLSSRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIVFLTEGPGIVDDEG
ELIREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL

Sequences:

>Translated_459_residues
MNSQTDLPPAQTGATTPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLSSRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIVFLTEGPGIVDDEG
ELIREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
>Mature_459_residues
MNSQTDLPPAQTGATTPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLSSRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIVFLTEGPGIVDDEG
ELIREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=436, Percent_Identity=45.4128440366972, Blast_Score=417, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6320913, Length=285, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49958; Mature: 49958

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQTDLPPAQTGATTPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHCCCEEEHHHHHHHHHH
AAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFAHTGIVRKIDAE
HCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCHHHCCHHHCCCHH
SIRHSLSSRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIVFLTEGPGIVDDEG
HHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCCCCHH
ELIREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLH
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHCCCCCCCHHHHHHHHHH
DGVGTMISYENLESLREATPDDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHD
CCCCHHEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHEECC
GVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLTHIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEC
TEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
CHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSQTDLPPAQTGATTPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHCCCEEEHHHHHHHHHH
AAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFAHTGIVRKIDAE
HCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCHHHCCHHHCCCHH
SIRHSLSSRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIVFLTEGPGIVDDEG
HHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCCCCHH
ELIREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLH
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHCCCCCCCHHHHHHHHHH
DGVGTMISYENLESLREATPDDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHD
CCCCHHEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHEECC
GVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLTHIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEC
TEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
CHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]