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The map label for this gene is moaE [H]

Identifier: 78066620

GI number: 78066620

Start: 2197386

End: 2197862

Strand: Reverse

Name: moaE [H]

Synonym: Bcep18194_A5151

Alternate gene names: 78066620

Gene position: 2197862-2197386 (Counterclockwise)

Preceding gene: 78066621

Following gene: 78066618

Centisome position: 59.5

GC content: 65.62

Gene sequence:

>477_bases
ATGGCAACGGTACGAATCCAGACCGACGACTTCGATCTGAACGCGGAAGTCGCGGCACTGCGCGCACGCAACCCGAAGAT
CGGCGCAGTCGCATGCTTCGTCGGCACGGTGCGTGATCTGAACGAAGGCGAATCGGTTGCGGCGATGGAGCTCGAGCACT
ATCCGGGGATGACCGAGAAGGCGCTCGAGAAGATTGCCGCCGAGGCCGGCCGACGCTGGCCGGGCATCGACGTCGCGATC
GTGCATCGCGTCGGCAAGCTCCTGCCGCTCGACCAGATCGTGATGGTCGCAACGGTTGCGTCGCACCGCGGCGATGCGTT
CGCGTCGTGCGAGTTCGTGATGGACTACCTGAAGACCGAGGCGCCGTTCTGGAAGAAGGAAACCACGCCGGACGGCGAGC
GCTGGGTTGATGCGCGCAGCACCGACGATGCCGCGCTCGCGCGCTGGGGCATCGAATCGGGCAATACGCGGCGCTGA

Upstream 100 bases:

>100_bases
ATGGCGTGCAATCACGAGATGACCGATCCCGACACGCGGCTCACCGAAGGCTGCGAGGTCGCTTTCTTTCCGCCGGTGAC
GGGCGGTTGAGGCACGGGCG

Downstream 100 bases:

>100_bases
GCACGGCGTGAGGGTGGTGCGGCGAGGTGCCGCGTGCGCGCAAGCGTCGCGCGTCACGGCTGCCCGTTACGCGTCCGGAT
CGCTGCTGCGCCCGATGATC

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MATVRIQTDDFDLNAEVAALRARNPKIGAVACFVGTVRDLNEGESVAAMELEHYPGMTEKALEKIAAEAGRRWPGIDVAI
VHRVGKLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTEAPFWKKETTPDGERWVDARSTDDAALARWGIESGNTRR

Sequences:

>Translated_158_residues
MATVRIQTDDFDLNAEVAALRARNPKIGAVACFVGTVRDLNEGESVAAMELEHYPGMTEKALEKIAAEAGRRWPGIDVAI
VHRVGKLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTEAPFWKKETTPDGERWVDARSTDDAALARWGIESGNTRR
>Mature_157_residues
ATVRIQTDDFDLNAEVAALRARNPKIGAVACFVGTVRDLNEGESVAAMELEHYPGMTEKALEKIAAEAGRRWPGIDVAIV
HRVGKLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTEAPFWKKETTPDGERWVDARSTDDAALARWGIESGNTRR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=33.6283185840708, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1787003, Length=139, Percent_Identity=52.5179856115108, Blast_Score=152, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17509279, Length=129, Percent_Identity=31.0077519379845, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356259, Length=128, Percent_Identity=34.375, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17402; Mature: 17271

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVRIQTDDFDLNAEVAALRARNPKIGAVACFVGTVRDLNEGESVAAMELEHYPGMTEK
CCEEEEECCCCCCCHHHHEEECCCCCCEEHHHHHHHHHCCCCCCCEEEEEHHHCCCCHHH
ALEKIAAEAGRRWPGIDVAIVHRVGKLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTE
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
APFWKKETTPDGERWVDARSTDDAALARWGIESGNTRR
CCCCCCCCCCCHHHEECCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATVRIQTDDFDLNAEVAALRARNPKIGAVACFVGTVRDLNEGESVAAMELEHYPGMTEK
CEEEEECCCCCCCHHHHEEECCCCCCEEHHHHHHHHHCCCCCCCEEEEEHHHCCCCHHH
ALEKIAAEAGRRWPGIDVAIVHRVGKLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTE
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
APFWKKETTPDGERWVDARSTDDAALARWGIESGNTRR
CCCCCCCCCCCHHHEECCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]