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The map label for this gene is clpB [H]

Identifier: 78066617

GI number: 78066617

Start: 2193238

End: 2195835

Strand: Reverse

Name: clpB [H]

Synonym: Bcep18194_A5148

Alternate gene names: 78066617

Gene position: 2195835-2193238 (Counterclockwise)

Preceding gene: 78066618

Following gene: 78066614

Centisome position: 59.44

GC content: 64.74

Gene sequence:

>2598_bases
ATGAGAATCGACAAGCTCACCACCAAGTTCCAGGAAGCACTCGCGGATGCGCAAAGCCTCGCAGCAGGCCGCGACAATCA
ATACATCGAACCCGTTCACGTTCTCGCGGCGCTGGTCGCGCAGCAGGACGGTTCCGCCCGCTCGCTGATGTCGCGCGCGG
GCGTTCACATTCAGGCGCTGCAAGGCGCGCTGAACGAAGCCATCTCGCGCCTGCCGCAAGTGACGGGCACGGGCGGCGAC
ATCCAGATCGGCCGTGAACTCTCCGGGCTGCTGAACCAGGCCGACAAGGAAGCGCAGAAGCTCAACGACACGTTCATCGC
GAGCGAGATGTTCCTGCTCGCCGTGTCCGACGACAAGGGCGACGCCGGCAAGCTCGCGCGCCAGCACGGCCTCACGCGCA
AGGCGCTGGAAGCCGCGATCGCCGCGGTGCGCGGCGGCTCGCAGGTGCACAGCCAGGACGCCGAAAGTCAGCGCGAGGCA
CTGAAGAAATACACGGTCGACCTGACCGAGCGCGCCCGGGCGGGCAAGCTCGATCCGGTGATCGGCCGCGACGACGAAAT
CCGCCGTTCGATCCAGATCCTGCAGCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGTGTCGGCAAGACGG
CGATCGTCGAAGGGCTCGCGCAGCGGATCGTCAACGGCGAAGTGCCCGAGACGCTCAAGGGCAAGCGCGTGCTGTCGCTC
GACATGGCCGCACTGCTCGCCGGCGCGAAGTATCGCGGCGAATTCGAGGAGCGCCTGAAGGCGGTGCTCAACGACATCGC
GAAGGATGAAGGCCAGACGATCGTCTTCATCGACGAAATCCACACGATGGTCGGTGCAGGCAAGGCCGAAGGCGCGATGG
ATGCGGGCAACATGCTGAAGCCGGCGCTGTCGCGCGGCGAGCTGCATTGCATCGGCGCGACCACGCTCGACGAATACCGC
AAGTACATCGAGAAGGATGCCGCGCTCGAGCGCCGCTTCCAGAAGGTGCTCGTCGACGAGCCGAGCGTCGAGGCGACGAT
CGCGATCCTGCGCGGGCTGCAGGAGAAGTACGAACTGCACCACGGCGTCGACATCACCGACCCGGCGATCGTCGCCGCGG
CCGAGCTGTCGCACCGCTACATCACCGATCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGACGAAGCCGCTTCGAAG
ATCAAGATGGAAATCGATTCGAAGCCCGAAGAGATGGACAAGCTCGATCGTCGTCTGATCCAGCTGAAGATCGAGCGCGA
AGCCGTGAAGAAGGAGCAGGACGAAGCGTCGCAGAAGCGCCTGCAGCTGATCGAGGAAGAGATCGAACGCCTCGGCCGCG
AGTACGCGGATCTGGAAGAGATCTGGACCGCCGAGAAGGCCGCGGTGCAGGGCAGCGCACAGCTGAAGGAAGAGATCGAG
AAGGTGCGTGCGGACATCGCACGGCTGCAGCGTGACGGCAAGCTGGAGAAGGTTGCCGAGCTGCAGTACGGCAAGCTGCC
GCAGCTCGAGGCGCAACTGAAGCAGGTCACGCAGGCCGAAGAGCAGGAGCAGCACAACCCGACGCGTCCGCGCCTGCTGC
GCACGCAGGTCGGCGCCGAGGAAATCGCGGAAGTCGTGTCGCGTTCGACCGGGATTCCGGTGTCGCGAATGATGCAGGGC
GAACGCGAGAAGCTGCTGCACATCGAGGAAAAGCTGCATGAGCGCGTGGTCGGCCAGCACGAGGCGATCAGTGCGGTGGC
CGACGCGATCCGCCGTTCGCGCGCGGGTCTCGCCGATCCGAACCGTCCGTACGGCTCGTTCCTGTTCCTCGGCCCGACGG
GTGTCGGCAAGACCGAGCTGTGCAAGGCGCTGGCGTCGTTCCTGTTCGATTCGGAAGAGCACCTGATCCGCATCGACATG
AGCGAGTTCATGGAGAAGCACAGCGTCGCGCGGCTGATCGGCGCGCCGCCGGGCTATGTCGGCTACGAGGAAGGCGGCTA
CCTGACGGAAGCCGTGCGTCGCAAGCCGTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCGCATCCGGACGTGTTCA
ACGTGCTGCTGCAGGTGCTTGACGACGGCCGCATGACGGACGGGCAGGGGCGCACGGTCGACTTCAAGAACACGGTGATC
GTGATGACGTCGAACCTCGGCTCGCAGGTGATCCAGGCGATGACGGGTGCGCCGCAGGAAGAGATCAAGGATGCCGTGTG
GCTCGAGGTGAAGCAGCATTTCCGCCCCGAGTTCCTGAACCGGATCGACGACGTCGTCGTGTTCCATGCGCTCGACCGCA
GCAACATCGAGTCGATCGCGAAGATCCAGCTCGCACGCCTGCACGACCGGCTTGCGAAGCTCGACATGGCGCTCGACGTG
TCGGAAGCGGCGCTCGAACAGATCGGCAAGGTCGGCTACGATCCGCTGTTCGGTGCGCGTCCGCTGAAGCGCGCGATCCA
GCAGGAGATCGAGAACCCGGTCGCGAAGCTCATCCTCGCGGGCCGCTTCGGTCCGAAGGATGTGATTCCGGTCGATATCC
ACGACGGCAAGTTCGTGTTCGACCGCGTCGTTCACTGA

Upstream 100 bases:

>100_bases
ATATCCATCGATTTTTGCGCTGAATCAACCCGAATTTCGCTTGAAAGCCGCATAACCATCCTCATCTTGGTGTTAATCGA
AAATTGGAGGTCTCGACTAA

Downstream 100 bases:

>100_bases
TCGCTGCCTGCCGCCCGGCTCGTACCGGGCGCACCAAAACAAACACCCCGCTCAGGCGGGGTGTTTGCTTATGGGGTGTC
GCAACGATGCAGGGTTCGAA

Product: AAA ATPase, ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHIQALQGALNEAISRLPQVTGTGGD
IQIGRELSGLLNQADKEAQKLNDTFIASEMFLLAVSDDKGDAGKLARQHGLTRKALEAAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDKLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEEIE
KVRADIARLQRDGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAEEIAEVVSRSTGIPVSRMMQG
EREKLLHIEEKLHERVVGQHEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMTGAPQEEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLARLHDRLAKLDMALDV
SEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDIHDGKFVFDRVVH

Sequences:

>Translated_865_residues
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHIQALQGALNEAISRLPQVTGTGGD
IQIGRELSGLLNQADKEAQKLNDTFIASEMFLLAVSDDKGDAGKLARQHGLTRKALEAAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDKLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEEIE
KVRADIARLQRDGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAEEIAEVVSRSTGIPVSRMMQG
EREKLLHIEEKLHERVVGQHEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMTGAPQEEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLARLHDRLAKLDMALDV
SEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDIHDGKFVFDRVVH
>Mature_865_residues
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHIQALQGALNEAISRLPQVTGTGGD
IQIGRELSGLLNQADKEAQKLNDTFIASEMFLLAVSDDKGDAGKLARQHGLTRKALEAAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDKLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEEIE
KVRADIARLQRDGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAEEIAEVVSRSTGIPVSRMMQG
EREKLLHIEEKLHERVVGQHEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMTGAPQEEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLARLHDRLAKLDMALDV
SEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDIHDGKFVFDRVVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=36.5771812080537, Blast_Score=197, Evalue=5e-50,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=66.2790697674419, Blast_Score=1164, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=398, Percent_Identity=41.4572864321608, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=52.3876404494382, Blast_Score=754, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=42.7745664739884, Blast_Score=692, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96000; Mature: 96000

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHIQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQIGRELSGLLNQADKEAQKLNDTFIASEMFLLAVSDDKG
HHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
DAGKLARQHGLTRKALEAAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCEEHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDKLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVRADIARLQRDGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
EIAEVVSRSTGIPVSRMMQGEREKLLHIEEKLHERVVGQHEAISAVADAIRRSRAGLADP
HHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQAMTGAPQEEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIA
EEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
KIQLARLHDRLAKLDMALDVSEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDIHDGKFVFDRVVH
CCCCCCCCEEEECCCCCHHHHHHCC
>Mature Secondary Structure
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHIQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQIGRELSGLLNQADKEAQKLNDTFIASEMFLLAVSDDKG
HHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
DAGKLARQHGLTRKALEAAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCEEHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDKLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVRADIARLQRDGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
EIAEVVSRSTGIPVSRMMQGEREKLLHIEEKLHERVVGQHEAISAVADAIRRSRAGLADP
HHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQAMTGAPQEEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIA
EEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
KIQLARLHDRLAKLDMALDVSEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDIHDGKFVFDRVVH
CCCCCCCCEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]