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The map label for this gene is engA

Identifier: 78066578

GI number: 78066578

Start: 2151077

End: 2152414

Strand: Reverse

Name: engA

Synonym: Bcep18194_A5109

Alternate gene names: 78066578

Gene position: 2152414-2151077 (Counterclockwise)

Preceding gene: 78066579

Following gene: 78066577

Centisome position: 58.27

GC content: 64.28

Gene sequence:

>1338_bases
ATGAAACCGGTCATTGCCCTTGTTGGGCGCCCCAATGTGGGGAAATCCACGCTGTTCAACCGGCTCACGCGCTCGCGTGA
TGCGCTGGTCGCCGACTTGCCGGGCCTGACGCGCGATCGCCATTACGGCGAAGGGCGCGTCGGCGAGCGGCCTTACCTGG
TCGTCGATACGGGCGGCTTCGAGCCCGTCGCGAAGGACGGCATCCTGCACGAGATGGCGCGCCAGACGCGGCAGGCCGTC
GAGGAAGCCGACGTCGTCGTGTTCATCGTCGACGGCCGCAACGGCCTTGCGCCGCAGGACAAGTCGATCGCCGACTACCT
GCGCAAGACCGGCCGGCCGATCTTCCTCGTCGTCAACAAGGCCGAGGGGATGAAGTACACGGCGGTCGCGACGGACTTCT
ACGAGCTCGGGCTCGGCGACCCGCGGGCGATCTCCGCCGCGCACGGCGACGGCGTGACCGACATGATCAACGAGGCGCTG
GAAGTCGCGTACGCCGGTCAGCCGGAGGAAGCGGACGAGGACGACCCGTCGCGCGGCATCAAGATCGCGATCGTCGGCCG
TCCGAACGTCGGCAAGTCGACGCTCGTGAACGCGCTGATCGGTGAAGATCGCGTGATCGCGTTCGACATGCCGGGCACGA
CGCGCGATTCGATCTACGTCGACTTCGAGCGTAACGGCAAGAAATACACGCTGATCGACACGGCCGGCCTGCGTCGTCGT
GGCAAGGTGTTCGAGGCGATCGAGAAATTCTCGGTCGTGAAGACGCTGCAGTCGATCTCCGATGCGAACGTCGTCATTCT
TCTGCTGGATGCGCAGCAGGACATTTCCGACCAGGACGCACACATCGCCGGCTTCGTCGTCGAACAGGGTCGCGCGCTCG
TGATCGGCGTCAACAAGTGGGACGGCCTCGACGAGCATGCGCGTGATCGCGCGAAAGCGGATTTGACCCGCAAGCTGAAA
TTCCTCGACTTCGCGAAATCGCATTACATTTCGGCCGCGAAGAAGACCGGCATCGGCGCGCTGATGCGCTCGGTCGACGA
CGCATACGCGGCGGCAATGGCGAAGCTGCCGACGCCGAAGCTCACGCGCGCGCTGATCGAGGCCGTCGAGTTCCAGCAGC
CGCGCCGTCGCGGCCCGGTGCGTCCGAAGCTGCGCTACGCGCACCAGGGCGGCCAGAATCCGCCGTTGATTGTCATCCAC
GGTAACGCGCTCGATGCGGTGACCGAAACGTACAAGCGTTACCTGGAAAACCGGTTCCGCGAAACTTTCTCACTGACAGG
GACTCCATTGCGCATAGAGTTCCGTTCGTCGAACAATCCGTACGCGGACAAGAGCTGA

Upstream 100 bases:

>100_bases
GCGCGCATCCGGCGCGGCGCGAATTCGTGATATTTTCATTCAGCGCAGCCGCCCGCAGCAGCGGGCCTCCCGCTGCTGCG
CATCACCGTAGAAAACACAG

Downstream 100 bases:

>100_bases
AGACGTCTGTTACACGCGTCACGCAAGGGGTTGGCCGCAAGGCCTATGCCCCGGGCGGGCCAGGCAAAATCGGCTATAGT
GTAGCGATTGGCGCCGGATC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYAGQPEEADEDDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRR
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARDRAKADLTRKLK
FLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIH
GNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSNNPYADKS

Sequences:

>Translated_445_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYAGQPEEADEDDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRR
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARDRAKADLTRKLK
FLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIH
GNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSNNPYADKS
>Mature_445_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYAGQPEEADEDDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRR
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARDRAKADLTRKLK
FLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIH
GNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSNNPYADKS

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=51.2820512820513, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=39.1304347826087, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.0645161290323, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=95, Percent_Identity=37.8947368421053, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=182, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49042; Mature: 49042

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEEADEDDPSRGI
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
KIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRR
EEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCHH
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKW
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCCC
DGLDEHARDRAKADLTRKLKFLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIHGNALDAVTETYKRYLENRFR
HHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ETFSLTGTPLRIEFRSSNNPYADKS
HHHCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEEADEDDPSRGI
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
KIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRR
EEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCHH
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKW
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCCC
DGLDEHARDRAKADLTRKLKFLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIHGNALDAVTETYKRYLENRFR
HHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ETFSLTGTPLRIEFRSSNNPYADKS
HHHCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA