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The map label for this gene is exbB [H]

Identifier: 78065826

GI number: 78065826

Start: 1309899

End: 1310687

Strand: Reverse

Name: exbB [H]

Synonym: Bcep18194_A4355

Alternate gene names: 78065826

Gene position: 1310687-1309899 (Counterclockwise)

Preceding gene: 78065827

Following gene: 78065825

Centisome position: 35.48

GC content: 67.68

Gene sequence:

>789_bases
ATGATCAACCGTACCCGCAAGGCCGCCCTGGTGACGGCACTGTTCCTCGCGGCCAGCGCCGCCCACGCCGCCACCGATAC
GGTGACGAATCCCTACGGCCTCGACGCGCTCTGGAAAGGCGGGGATTTCATCGCACGAGGCACGCTGCTCATCCTGGTCG
TCATGTCGATGGGCAGCTGGTACATCATCGTCGCGAAACTGCTCGAGCAAGCGCGTGTCCTGCGCCGCGCGAAGGCAGCG
GAAACGGGTTTCTGGAAAGCGGGCAGTCTCAGCGAAGGCACGAAGAAACTGGACACCGGCAGCCCGTTCCGCTTCATCGC
CGAAACAGGTCTCGCGGCATTCGACCATCACGAAGGCGCGCTGGTCGAACAGGTCGACCTCAACCAGTGGGTCGCGGCGG
CCATCGAGCGGGCGACCACGTCCGTCTCGAGCCGCCTGCAGGACGGCCTCGCGTTTCTCGGCACCGTCGGCTCGACCGCG
CCGTTCATCGGACTGTTCGGCACGGTGTGGGGCATCTATCACGCGCTGACTGCGATCGGCATCGCGGGCCAGGCCTCCAT
CGACAAGGTCGCGGGGCCGGTCGGCGAAGCGCTGATCATGACCGCGATCGGCCTGGCCGTCGCGGTGCCCGCCGTGCTCG
GCTACAACTGGCTCGTGCGCCGCAACAAGGCGGTGATGGAGCGCGTGCGCGGGTTTTCGACGGAATTGCACATCGTCCTC
CTGACCGGCACGACCACGGCCGCCGCCGCCGCCGCGACCAAGGCCGCCGCCCTCACCCGCGTGGGGTAA

Upstream 100 bases:

>100_bases
AGGAAGTCCGCGTGCAGGTGCCCTTCTCTTTCAAGCTCGATTGAGGCTGCGCTCGACAGCCGTTCCCTTTCTACTTGCCA
ACGCATTTCAGGAGACGTTC

Downstream 100 bases:

>100_bases
GCCATGGCCATGACCGTAGGCCCGCGCGAGGGCGCCGAGCACGACGAGACCATGTCGTCCATCAACACGACGCCACTGGT
CGACGTGATGCTGGTGCTGC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MINRTRKAALVTALFLAASAAHAATDTVTNPYGLDALWKGGDFIARGTLLILVVMSMGSWYIIVAKLLEQARVLRRAKAA
ETGFWKAGSLSEGTKKLDTGSPFRFIAETGLAAFDHHEGALVEQVDLNQWVAAAIERATTSVSSRLQDGLAFLGTVGSTA
PFIGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKAVMERVRGFSTELHIVL
LTGTTTAAAAAATKAAALTRVG

Sequences:

>Translated_262_residues
MINRTRKAALVTALFLAASAAHAATDTVTNPYGLDALWKGGDFIARGTLLILVVMSMGSWYIIVAKLLEQARVLRRAKAA
ETGFWKAGSLSEGTKKLDTGSPFRFIAETGLAAFDHHEGALVEQVDLNQWVAAAIERATTSVSSRLQDGLAFLGTVGSTA
PFIGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKAVMERVRGFSTELHIVL
LTGTTTAAAAAATKAAALTRVG
>Mature_262_residues
MINRTRKAALVTALFLAASAAHAATDTVTNPYGLDALWKGGDFIARGTLLILVVMSMGSWYIIVAKLLEQARVLRRAKAA
ETGFWKAGSLSEGTKKLDTGSPFRFIAETGLAAFDHHEGALVEQVDLNQWVAAAIERATTSVSSRLQDGLAFLGTVGSTA
PFIGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKAVMERVRGFSTELHIVL
LTGTTTAAAAAATKAAALTRVG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=222, Percent_Identity=34.2342342342342, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789381, Length=193, Percent_Identity=30.0518134715026, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 27434; Mature: 27434

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRTRKAALVTALFLAASAAHAATDTVTNPYGLDALWKGGDFIARGTLLILVVMSMGSW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCH
YIIVAKLLEQARVLRRAKAAETGFWKAGSLSEGTKKLDTGSPFRFIAETGLAAFDHHEGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCHHHHHHHCCHHHCCCCCC
LVEQVDLNQWVAAAIERATTSVSSRLQDGLAFLGTVGSTAPFIGLFGTVWGIYHALTAIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
IAGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKAVMERVRGFSTELHIVL
CCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHCCCCEEEEEE
LTGTTTAAAAAATKAAALTRVG
EECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINRTRKAALVTALFLAASAAHAATDTVTNPYGLDALWKGGDFIARGTLLILVVMSMGSW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCH
YIIVAKLLEQARVLRRAKAAETGFWKAGSLSEGTKKLDTGSPFRFIAETGLAAFDHHEGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCHHHHHHHCCHHHCCCCCC
LVEQVDLNQWVAAAIERATTSVSSRLQDGLAFLGTVGSTAPFIGLFGTVWGIYHALTAIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
IAGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKAVMERVRGFSTELHIVL
CCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHCCCCEEEEEE
LTGTTTAAAAAATKAAALTRVG
EECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]