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The map label for this gene is moaA

Identifier: 78065694

GI number: 78065694

Start: 1156253

End: 1157365

Strand: Reverse

Name: moaA

Synonym: Bcep18194_A4222

Alternate gene names: 78065694

Gene position: 1157365-1156253 (Counterclockwise)

Preceding gene: 78065695

Following gene: 78065693

Centisome position: 31.33

GC content: 68.28

Gene sequence:

>1113_bases
ATGTCCCGACGCATCATTCCTCTCGCCGACGTCAGCGGGATGCCGGACGTCTCCGGCGTCGCGCACGCCCCGGACGGCAC
GCTGGCCGACACGTTCGCCAGGCCGCTGCGCGACCTGCGCATTTCGGTGACGGATCGCTGCAACTTCCGCTGCGTGTACT
GCATGCCGCGCGCCGTCTTCGACAAGGACTACCCGTTCCTGCCGCACAGCGCCCTGCTCACGCACGAGGAAATCGAACGC
GTGGCGCGACTCTTTGTCGCACATGGCGTCGAGAAGATCCGCATCACCGGTGGCGAGCCGCTGCTGCGCAAGAATCTCGA
ATTCCTGATCGAGCGCCTCGCACGCCTGACCACGCATGACGGCCGCCCGATCGACCTGACGCTCACGACCAACGGTTCGC
TGCTCGCTCGCAAGGCGCGCGCGCTGAAGGACGCCGGGCTCACGCGCGTGACGGTCAGCCTCGACGCGCTCGACGATACG
TTGTTCAAGCGCATGAACGATGCCGAATTCGCGAGCGCCGACGTGCTCGACGGCATCTTCGCGGCCCAGGCCGTGGGCCT
CGCGCCGGTCAAGGTCAACATGGTCGTGAAGCGCGGCACCAACGACAGCGAGATCCTGCCGATGGCCGAGCGTTTCCGCG
GGACCGGCGTGATCCTGCGCTTCATCGAATACATGGACGTCGGCACGTCGAACGGCTGGAACATGACCGAGGTGCTGCCG
TCGGCGGACGTCATCGCCCGGCTCGCCGAACACTTCCCGCTCGTGCCGCTCGATCCCCACACGGCGGCCGAAACCGCGCA
GCGCTGGGGCTATGCGGACGGCAGCGGCGAGATCGGCGTGATTTCGAGCGTCACGCAGGCGTTCTGCGGCGACTGCACGC
GCGCGCGGCTGTCGACCGAAGGCAAGCTGTACCTGTGCCTGTTCGCGTCGACGGGCCACGACCTGCGCGCGCTCGTACGC
GGCGGCGCGAGCGACGCCGAGATCGCGACCGCGATCGCCCGCATCTGGCAGGCCCGCACCGACCGTTATTCGCAGCTGCG
CGGCAGCGCGTCTGCCGACGCCGTGCCCGACGGCGCCGGCAAGCGGGTCGAAATGTCATATATCGGCGGCTGA

Upstream 100 bases:

>100_bases
CTCCGGCGGGCTTTTTCACGTCCGCGCTGCGGGTTTCCGCCCACCGGCCCGACCCGCCGCTTGCGGCTAAAATAGAGGTC
TGGTTCGCACTTCTTTCAAC

Downstream 100 bases:

>100_bases
CGCACGCCGCCCTTCCTGCCCGCCGACCATGCCCGCTTCCGCCTCTCCCTCGATTGCCGGCCTGCTGCTCGCAGGCGGGC
GTGCCACACGCATGGATGGT

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSRRIIPLADVSGMPDVSGVAHAPDGTLADTFARPLRDLRISVTDRCNFRCVYCMPRAVFDKDYPFLPHSALLTHEEIER
VARLFVAHGVEKIRITGGEPLLRKNLEFLIERLARLTTHDGRPIDLTLTTNGSLLARKARALKDAGLTRVTVSLDALDDT
LFKRMNDAEFASADVLDGIFAAQAVGLAPVKVNMVVKRGTNDSEILPMAERFRGTGVILRFIEYMDVGTSNGWNMTEVLP
SADVIARLAEHFPLVPLDPHTAAETAQRWGYADGSGEIGVISSVTQAFCGDCTRARLSTEGKLYLCLFASTGHDLRALVR
GGASDAEIATAIARIWQARTDRYSQLRGSASADAVPDGAGKRVEMSYIGG

Sequences:

>Translated_370_residues
MSRRIIPLADVSGMPDVSGVAHAPDGTLADTFARPLRDLRISVTDRCNFRCVYCMPRAVFDKDYPFLPHSALLTHEEIER
VARLFVAHGVEKIRITGGEPLLRKNLEFLIERLARLTTHDGRPIDLTLTTNGSLLARKARALKDAGLTRVTVSLDALDDT
LFKRMNDAEFASADVLDGIFAAQAVGLAPVKVNMVVKRGTNDSEILPMAERFRGTGVILRFIEYMDVGTSNGWNMTEVLP
SADVIARLAEHFPLVPLDPHTAAETAQRWGYADGSGEIGVISSVTQAFCGDCTRARLSTEGKLYLCLFASTGHDLRALVR
GGASDAEIATAIARIWQARTDRYSQLRGSASADAVPDGAGKRVEMSYIGG
>Mature_369_residues
SRRIIPLADVSGMPDVSGVAHAPDGTLADTFARPLRDLRISVTDRCNFRCVYCMPRAVFDKDYPFLPHSALLTHEEIERV
ARLFVAHGVEKIRITGGEPLLRKNLEFLIERLARLTTHDGRPIDLTLTTNGSLLARKARALKDAGLTRVTVSLDALDDTL
FKRMNDAEFASADVLDGIFAAQAVGLAPVKVNMVVKRGTNDSEILPMAERFRGTGVILRFIEYMDVGTSNGWNMTEVLPS
ADVIARLAEHFPLVPLDPHTAAETAQRWGYADGSGEIGVISSVTQAFCGDCTRARLSTEGKLYLCLFASTGHDLRALVRG
GASDAEIATAIARIWQARTDRYSQLRGSASADAVPDGAGKRVEMSYIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI22027536, Length=306, Percent_Identity=37.5816993464052, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI116734668, Length=305, Percent_Identity=37.7049180327869, Blast_Score=201, Evalue=6e-52,
Organism=Escherichia coli, GI1786999, Length=346, Percent_Identity=34.971098265896, Blast_Score=158, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17561210, Length=328, Percent_Identity=33.2317073170732, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=339, Percent_Identity=31.2684365781711, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI32566329, Length=328, Percent_Identity=31.4024390243902, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI28574488, Length=347, Percent_Identity=32.8530259365994, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28574490, Length=322, Percent_Identity=34.472049689441, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 40245; Mature: 40113

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIIPLADVSGMPDVSGVAHAPDGTLADTFARPLRDLRISVTDRCNFRCVYCMPRAVF
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECCCCCEEEEECCHHHH
DKDYPFLPHSALLTHEEIERVARLFVAHGVEKIRITGGEPLLRKNLEFLIERLARLTTHD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
GRPIDLTLTTNGSLLARKARALKDAGLTRVTVSLDALDDTLFKRMNDAEFASADVLDGIF
CCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
AAQAVGLAPVKVNMVVKRGTNDSEILPMAERFRGTGVILRFIEYMDVGTSNGWNMTEVLP
HHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHCC
SADVIARLAEHFPLVPLDPHTAAETAQRWGYADGSGEIGVISSVTQAFCGDCTRARLSTE
CHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCC
GKLYLCLFASTGHDLRALVRGGASDAEIATAIARIWQARTDRYSQLRGSASADAVPDGAG
CCEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KRVEMSYIGG
CEEEEEECCC
>Mature Secondary Structure 
SRRIIPLADVSGMPDVSGVAHAPDGTLADTFARPLRDLRISVTDRCNFRCVYCMPRAVF
CCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECCCCCEEEEECCHHHH
DKDYPFLPHSALLTHEEIERVARLFVAHGVEKIRITGGEPLLRKNLEFLIERLARLTTHD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
GRPIDLTLTTNGSLLARKARALKDAGLTRVTVSLDALDDTLFKRMNDAEFASADVLDGIF
CCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
AAQAVGLAPVKVNMVVKRGTNDSEILPMAERFRGTGVILRFIEYMDVGTSNGWNMTEVLP
HHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHCC
SADVIARLAEHFPLVPLDPHTAAETAQRWGYADGSGEIGVISSVTQAFCGDCTRARLSTE
CHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCC
GKLYLCLFASTGHDLRALVRGGASDAEIATAIARIWQARTDRYSQLRGSASADAVPDGAG
CCEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KRVEMSYIGG
CEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]