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The map label for this gene is yggV [C]

Identifier: 78065576

GI number: 78065576

Start: 1033373

End: 1033999

Strand: Reverse

Name: yggV [C]

Synonym: Bcep18194_A4104

Alternate gene names: 78065576

Gene position: 1033999-1033373 (Counterclockwise)

Preceding gene: 78065577

Following gene: 78065575

Centisome position: 27.99

GC content: 70.49

Gene sequence:

>627_bases
ATGCCGGACGACCACACCATCGCGCCGCTGTCGCGCATCGTTCTCGCGTCGAACAACGCCGGCAAGCTGCGCGAATTCAC
CGCGCTGTTCTCGACGGTCGGCATCGAGATCGTCCCGCAGGGCGACCTCGCGGTGCCCGAGGCGGAAGAACCGTTCGGCA
CCTTCATCGAGAATGCGCTGACGAAAGCGCGCCACGCGTCGCGGCTCACCGGGCTGCCGGCGATCGCCGACGATTCGGGC
CTGTGCGTGCGCGTGCTGCGCGGCGCGCCGGGCGTCTATTCGGCGCGCTACGCGCAGCGCGCGGGCCGCGACAAGGGCGA
CGCGGCGAACAACGCGTATCTCGTCGAGCAACTGCGCGGCGTCGACGACCGGCGCGCATACTACTGCTGCGTGCTCGCGC
TCGTGCGCCATGCGGACGACCCCGAACCGCTGTTCGCCGAAGGGCGCTGGTCGGGCGAGATCGTCGACACGCCGCGCGGC
GAGCACGGATTCGGCTACGACCCGTATTTCTACCTGCCGTCGCTCGGCGCGACGGCCGCCGAACTCGAGCCGGCCGTGAA
GAACACGCACAGCCATCGCGCGCTGGCGCTGAAGGCGCTGCTGGCGCGGCTCGCGGAGGAAGCATGA

Upstream 100 bases:

>100_bases
GTGCCGTTCTCGCGCGCCGAGATGAATGCGCTGCTCGACCTCGCGCAAGGCGGGATCGCCGAGCTCGTGCAGCTCCAGAA
AGACGTGCTGGGCGCCTGAC

Downstream 100 bases:

>100_bases
GCATGCCCGATACCCGTTCGCCGACGGAGGTTGCATGAGCCAGGCCGCGGAAACCGGCGCGCGCGTTGTCGCGACCTTCA
CGTCGCCCGGCCAGGTGCGG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPDDHTIAPLSRIVLASNNAGKLREFTALFSTVGIEIVPQGDLAVPEAEEPFGTFIENALTKARHASRLTGLPAIADDSG
LCVRVLRGAPGVYSARYAQRAGRDKGDAANNAYLVEQLRGVDDRRAYYCCVLALVRHADDPEPLFAEGRWSGEIVDTPRG
EHGFGYDPYFYLPSLGATAAELEPAVKNTHSHRALALKALLARLAEEA

Sequences:

>Translated_208_residues
MPDDHTIAPLSRIVLASNNAGKLREFTALFSTVGIEIVPQGDLAVPEAEEPFGTFIENALTKARHASRLTGLPAIADDSG
LCVRVLRGAPGVYSARYAQRAGRDKGDAANNAYLVEQLRGVDDRRAYYCCVLALVRHADDPEPLFAEGRWSGEIVDTPRG
EHGFGYDPYFYLPSLGATAAELEPAVKNTHSHRALALKALLARLAEEA
>Mature_207_residues
PDDHTIAPLSRIVLASNNAGKLREFTALFSTVGIEIVPQGDLAVPEAEEPFGTFIENALTKARHASRLTGLPAIADDSGL
CVRVLRGAPGVYSARYAQRAGRDKGDAANNAYLVEQLRGVDDRRAYYCCVLALVRHADDPEPLFAEGRWSGEIVDTPRGE
HGFGYDPYFYLPSLGATAAELEPAVKNTHSHRALALKALLARLAEEA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=191, Percent_Identity=31.9371727748691, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI31657144, Length=145, Percent_Identity=35.1724137931034, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=53.2994923857868, Blast_Score=197, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17556833, Length=192, Percent_Identity=32.2916666666667, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=30.8510638297872, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22486; Mature: 22354

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDHTIAPLSRIVLASNNAGKLREFTALFSTVGIEIVPQGDLAVPEAEEPFGTFIENAL
CCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHH
TKARHASRLTGLPAIADDSGLCVRVLRGAPGVYSARYAQRAGRDKGDAANNAYLVEQLRG
HHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHC
VDDRRAYYCCVLALVRHADDPEPLFAEGRWSGEIVDTPRGEHGFGYDPYFYLPSLGATAA
CCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEECCCCCCCCCCCCCEEECCCCCCHHH
ELEPAVKNTHSHRALALKALLARLAEEA
HHCHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDDHTIAPLSRIVLASNNAGKLREFTALFSTVGIEIVPQGDLAVPEAEEPFGTFIENAL
CCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHH
TKARHASRLTGLPAIADDSGLCVRVLRGAPGVYSARYAQRAGRDKGDAANNAYLVEQLRG
HHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHC
VDDRRAYYCCVLALVRHADDPEPLFAEGRWSGEIVDTPRGEHGFGYDPYFYLPSLGATAA
CCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEECCCCCCCCCCCCCEEECCCCCCHHH
ELEPAVKNTHSHRALALKALLARLAEEA
HHCHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA