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The map label for this gene is tcp [H]

Identifier: 78065556

GI number: 78065556

Start: 1013498

End: 1015033

Strand: Direct

Name: tcp [H]

Synonym: Bcep18194_A4084

Alternate gene names: 78065556

Gene position: 1013498-1015033 (Clockwise)

Preceding gene: 78065555

Following gene: 78065558

Centisome position: 27.44

GC content: 69.6

Gene sequence:

>1536_bases
ATGAAGCTGAGCTACAAGATTCCCCTCGCATTCGCCGTCGCGCTGCTGCTGATGTTCTGTGGCGCGCTGTACGGTATCCA
TATTCTCAATCGGTCGATCGATACGTTCGCCGAAGACGTGCAGACGAACGTCGGCGACGAACGGCTCGTGTCGGCCACGC
TCGTCCAGTTCAAGCTGCAAGTGCAGGAATGGAAGGACACGCTGTTGCGCGGCAAGCAGCCCGGCAAGCTCGACCAGTAC
TGGCAGGCGTTCCAGACGCGCGAGCGGACGGTCGATACGCTCGCCGCGCAGCTCGTTCACCAGTTGCCGCCCGGCGAGAG
CCGCTCGCTCGTCGAGCAGTTCATGCGCGCGCACACGGCGATGGGCGAAGGTTACCGGCGCGGGTTCGACGCATTCAAGG
CTGCCGGCTTCGAGCCGTCGGCCGGCGATGCCGCGGTGGCGGGCGTCGACCGCGAACCGGCGGCGCTGCTGGAGCGGGCC
GCGAAGTCGATCGCCGACGAGAGTGCCGCCGTGTCGGCGCAGGCGAGCCGCGACGCGCAGCACGCGACCACCGCGAGCCT
CGTGCTGATGCTGGTCGTGCTCGGCGTCGCGATGGTCGGCGCGTTCCTGTTCAGCCGCGCGATCCTGCGTCCGCTCGACC
GTGCGGTGGCGTGCGCGCAGGCCGTCGCCGAAGGCGACCTGACGCGCGACGTCGACACGGCCGGCCGCGACGAGATCGCC
GATCTGCTGCGCGCGTTGCAGACGATGCAGGCGAGCCTGTCGGGCGTCGTGCTCGAAGTGCGTACGCACGCCGAAGCCGT
CGCGACGGCGAGCGCACAGATCGCGTCGGGCAACCACGACCTGTCGGCGCGTACCGAGGCGCAGGCTGCATCGCTCGAGG
AGACCGCCGCCAGCATGACCGAGCTCACGGGCATCGTCCGCCAGTCGGCCGAACACGCGCAGCACGCGGCGCAATTGGCG
CACGACGCGTCGAACATCGCCGCGGCGGGCGGCGGCGTGATGACGGATGCCGTCGGCACGATGAACGGCATCGCCGACAG
CTCCGCAAAGGTCGGCGAGATCATCGCGGTGATCGACGGCATCGCGTTCCAGACCAACATCCTCGCGCTGAACGCGGCGG
TCGAGGCGGCTCGCGCGGGCGAACAGGGGCGCGGCTTCGCCGTCGTCGCGGCGGAAGTGCGTACGCTCGCGCAACGCAGC
GCCGCCGCGGCGAAGGAGATCAAGGGACTCATCGAGCAGTCGACGAAGCGGGTCGACGAGGGTGCCGTGCTGATCGGCCG
TGCGGGCGAATCGATTCACGAGATCGTCGGCGCGGTGCAGCGCGTCACGACGATCGTCGGCGAGATCTCGTCCGCATCGC
AGGAGCAGAGCGGCGGCATCCAGCAGGTGAACATCGCGGTGACGCAGATGGACGAAGCGACGCAGCGCAACGCCGCGCTC
GTCGAGCAGGCCTCGGCCGCGACGCAGGCGCTGGCCGAGCAGGCGAGCGCGCTGCGGCACGCGGTGGCCGTGTTCAGGCT
GCCGGAAATGGCGTGA

Upstream 100 bases:

>100_bases
GCTTTCTTCAGCTTTAAGCCCGCGCTTCCCGCGCCGTTAACACGGGGCGGCGGCCGGCGCCCGTGCCGGACCGCTTCGTT
CCCCGTCGATCCAAGGTCCC

Downstream 100 bases:

>100_bases
CGGCTGCGCCGTCGCGCCGGACTTCGACGGAACCGGGGGCCGGCGCGTCGGCGCCGGTTTCCCCCGGCCCGTCTCCCGCG
ATCACGCCGCGGCCGGATAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MKLSYKIPLAFAVALLLMFCGALYGIHILNRSIDTFAEDVQTNVGDERLVSATLVQFKLQVQEWKDTLLRGKQPGKLDQY
WQAFQTRERTVDTLAAQLVHQLPPGESRSLVEQFMRAHTAMGEGYRRGFDAFKAAGFEPSAGDAAVAGVDREPAALLERA
AKSIADESAAVSAQASRDAQHATTASLVLMLVVLGVAMVGAFLFSRAILRPLDRAVACAQAVAEGDLTRDVDTAGRDEIA
DLLRALQTMQASLSGVVLEVRTHAEAVATASAQIASGNHDLSARTEAQAASLEETAASMTELTGIVRQSAEHAQHAAQLA
HDASNIAAAGGGVMTDAVGTMNGIADSSAKVGEIIAVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRS
AAAAKEIKGLIEQSTKRVDEGAVLIGRAGESIHEIVGAVQRVTTIVGEISSASQEQSGGIQQVNIAVTQMDEATQRNAAL
VEQASAATQALAEQASALRHAVAVFRLPEMA

Sequences:

>Translated_511_residues
MKLSYKIPLAFAVALLLMFCGALYGIHILNRSIDTFAEDVQTNVGDERLVSATLVQFKLQVQEWKDTLLRGKQPGKLDQY
WQAFQTRERTVDTLAAQLVHQLPPGESRSLVEQFMRAHTAMGEGYRRGFDAFKAAGFEPSAGDAAVAGVDREPAALLERA
AKSIADESAAVSAQASRDAQHATTASLVLMLVVLGVAMVGAFLFSRAILRPLDRAVACAQAVAEGDLTRDVDTAGRDEIA
DLLRALQTMQASLSGVVLEVRTHAEAVATASAQIASGNHDLSARTEAQAASLEETAASMTELTGIVRQSAEHAQHAAQLA
HDASNIAAAGGGVMTDAVGTMNGIADSSAKVGEIIAVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRS
AAAAKEIKGLIEQSTKRVDEGAVLIGRAGESIHEIVGAVQRVTTIVGEISSASQEQSGGIQQVNIAVTQMDEATQRNAAL
VEQASAATQALAEQASALRHAVAVFRLPEMA
>Mature_511_residues
MKLSYKIPLAFAVALLLMFCGALYGIHILNRSIDTFAEDVQTNVGDERLVSATLVQFKLQVQEWKDTLLRGKQPGKLDQY
WQAFQTRERTVDTLAAQLVHQLPPGESRSLVEQFMRAHTAMGEGYRRGFDAFKAAGFEPSAGDAAVAGVDREPAALLERA
AKSIADESAAVSAQASRDAQHATTASLVLMLVVLGVAMVGAFLFSRAILRPLDRAVACAQAVAEGDLTRDVDTAGRDEIA
DLLRALQTMQASLSGVVLEVRTHAEAVATASAQIASGNHDLSARTEAQAASLEETAASMTELTGIVRQSAEHAQHAAQLA
HDASNIAAAGGGVMTDAVGTMNGIADSSAKVGEIIAVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRS
AAAAKEIKGLIEQSTKRVDEGAVLIGRAGESIHEIVGAVQRVTTIVGEISSASQEQSGGIQQVNIAVTQMDEATQRNAAL
VEQASAATQALAEQASALRHAVAVFRLPEMA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=341, Percent_Identity=51.6129032258064, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=57.6158940397351, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=53.2307692307692, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI2367378, Length=321, Percent_Identity=55.7632398753894, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1789453, Length=322, Percent_Identity=37.888198757764, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 53563; Mature: 53563

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]