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The map label for this gene is ftsK2 [H]

Identifier: 78065550

GI number: 78065550

Start: 1005577

End: 1007886

Strand: Direct

Name: ftsK2 [H]

Synonym: Bcep18194_A4078

Alternate gene names: 78065550

Gene position: 1005577-1007886 (Clockwise)

Preceding gene: 78065546

Following gene: 78065551

Centisome position: 27.22

GC content: 67.36

Gene sequence:

>2310_bases
ATGGCAAAAGCTCCTTATTCCGCCCAGGCACAGGCGTTGCCGCACCGGATGTCGAAGCTCCTCACGGAGATCCGCTGGAT
TCTCCAGGTCGCGCTCTGCGCATTTCTGGTGATGGCCCTGCTGAGCTACAGCCGGCGCGATCCGAGCTGGACGCACGCCG
CCCAGGTGGACCACATCACGAACTGGGCCGGCCGCGTCGGCGCCTGGACGGCCGACATCATCCTGCTGCTGTTCGGCCTG
TCGGCCTACTGGTTGATCGTGCCGCTCGCGCGGCGCATCGCCGTCAACTATCGCCGCATCACGCGCCATGAGGCGGTCCC
GGACGAACCCGAGCGGCCGATTGGCTGGCTCACCGAAATCCTCGCGTTCGTGCTCGTCGTGCTGGCATGCGACGGCATCG
AGGCGCTGCGCATGTGGTCGCTGAAGGTGCAGTTGCCGCGTGCGCCGGGCGGCGTCGTCGGCGAGGCCGTCGCGGGCGCG
ATGTCGCACGCGTTCGGTTTCACGGGCGGCACGCTGCTGCTGCTGATCGCACTGGCGATCGGCCTGTCGCTGTATTTCCG
CTTCTCGTGGCTGTCGGTCGCCGAGCGTGTCGGCGGTGCGATCCTGTCCGCCGTCAACGTCGCGAAGCTGCGCCGCGAGG
CCGAGCGCGACCGCAAGCTCGGCGAGGCCGCGGCCGTGCGCCGCGAAGGCAAGGTCGAAGAAGAGCGCGTGCGCATCGAG
GATCACGAGCCCGTGACGATCGTGCCGCCGGTCGTCACGCCTGCCAAGTCCGAGCGCGTCGAGCGCGAGCGCCAGGTGCC
GCTCTTCACCGACCTGCCGGGCGATTCGACGCTGCCGGCGGTATCGCTGCTCGACCCGGAGCCGAAGGCGCAGGAGGCGA
TTTCCGCCGACACGCTCGAATTCACGTCGCGCCTGATCGAGAAGAAGCTGAAGGACTTCGGCGTCGAGGCGAGTGTCGTC
GCCGCGTATCCGGGCCCGGTCGTCACGCGCTACGAGATCGAGCCGGCCACCGGCGTGAAGGGCAGCCAGATCGTCAACCT
CGCGAAGGATCTCGCGCGCTCGCTGTCGCTCGTGTCGATCCGCGTCGTCGAGACGATTCCCGGCAAGAACTACATGGCGC
TCGAGCTGCCGAACCAGCGCCGCCAGACGGTCCACCTGTCCGAGATCATCGGTTCCGAGGTGTACGCGGCCGCCTCGTCG
GCGCTGACGCTGAGCCTCGGCAAGGACATCGGCGGCAAGCCGGTGTGCGCGGATCTCGCGAAGATGCCGCACCTGCTGGT
GGCCGGCACGACCGGTTCGGGCAAGTCGGTCGGGATCAACGCGATGATCCTGTCGCTGCTGTATAAAGCGACCGCCGAGC
AGGTACGCCTGATCCTGATCGATCCGAAGATGCTCGAAATGAGCGTCTACGAAGGCATTCCGCACCTGCTGTGCCCGGTC
GTCACCGACATGCGCCAGGCCGGCAACGCGCTGAACTGGACGGTCGCGGAGATGGAGCGCCGCTACAAGCTGATGAGCAA
GCTCGGCGTGCGCAATCTCGCGGGCTACAACAACAAGATCGACGAGGCCGCGAAGCGCGAGGAGAAGCTGCCGAATCCGT
TCAGCCTGACGCCGGAAGATCCTGAGCCGCTCGGCCGCCTGCCGAACATCGTCGTCGTGATCGACGAGCTGGCCGACCTG
ATGATGGTCGTCGGCAAGAAGGTCGAGGAACTGATTGCACGGATCGCGCAGAAGGCGCGCGCGGCCGGCATCCACCTGAT
CCTCGCGACGCAGCGTCCGTCGGTCGACGTGATCACCGGCCTCATCAAGGCCAACGTGCCGACGCGGATCGCGTTCCAGG
TGTCGTCGAAGATCGACTCGCGCACGATTCTCGACCAGATGGGCGCCGAATCGCTGCTCGGGATGGGCGACATGCTGTAT
CTGGCGCCGGGCACCGGGCTGCCGGTGCGCGTGCACGGCGCGTTCGTCGCGGATGACGAAGTGCACCGCGTCGTCGAGAA
GCTCAAGGAGCAGGGCGAGCCGAACTACATCGAGGGCCTGCTCGAAGGCGGCACCGCCGACGGCGACGAGGGCTCGGCCG
GTGCGGGAACCGGCGAAGGCGGCGACGAGTCTGATCCGCTGTACGACCAGGCGGTCGAGATCGTCATCAAGAACCGCCGC
GCGTCGATCTCGCTCGTGCAGCGCCACCTGCGGATCGGCTATAACCGCGCGGCGCGGCTGCTCGAGCAGATGGAGCAGTC
GGGGCTCGTGTCGGCGATGTCGTCGAGCGGCAACCGCGAAATTCTTGTGCCGGCGCGCGACGCGGAATGA

Upstream 100 bases:

>100_bases
TATGTAACCGTCATTTACACTTGGCGGCCCGGTGCAGCGTTTACAATAAGCGGGATCGAACGACAGGCGGGCGCATGGCC
CGTCCTCTTTATACGGATTC

Downstream 100 bases:

>100_bases
GTCCGCGGCGTTCGCAGCGCCGGCCACCCAGGGAGAAAACCGCAATATGCAGCAACATTCGTTCGCAATGTCCCTTCGTT
CGACGCGGCGCTGGCTCGGC

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MAKAPYSAQAQALPHRMSKLLTEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHITNWAGRVGAWTADIILLLFGL
SAYWLIVPLARRIAVNYRRITRHEAVPDEPERPIGWLTEILAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGA
MSHAFGFTGGTLLLLIALAIGLSLYFRFSWLSVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREGKVEEERVRIE
DHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPAVSLLDPEPKAQEAISADTLEFTSRLIEKKLKDFGVEASVV
AAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNYMALELPNQRRQTVHLSEIIGSEVYAAASS
ALTLSLGKDIGGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVYEGIPHLLCPV
VTDMRQAGNALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKLPNPFSLTPEDPEPLGRLPNIVVVIDELADL
MMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLY
LAPGTGLPVRVHGAFVADDEVHRVVEKLKEQGEPNYIEGLLEGGTADGDEGSAGAGTGEGGDESDPLYDQAVEIVIKNRR
ASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPARDAE

Sequences:

>Translated_769_residues
MAKAPYSAQAQALPHRMSKLLTEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHITNWAGRVGAWTADIILLLFGL
SAYWLIVPLARRIAVNYRRITRHEAVPDEPERPIGWLTEILAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGA
MSHAFGFTGGTLLLLIALAIGLSLYFRFSWLSVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREGKVEEERVRIE
DHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPAVSLLDPEPKAQEAISADTLEFTSRLIEKKLKDFGVEASVV
AAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNYMALELPNQRRQTVHLSEIIGSEVYAAASS
ALTLSLGKDIGGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVYEGIPHLLCPV
VTDMRQAGNALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKLPNPFSLTPEDPEPLGRLPNIVVVIDELADL
MMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLY
LAPGTGLPVRVHGAFVADDEVHRVVEKLKEQGEPNYIEGLLEGGTADGDEGSAGAGTGEGGDESDPLYDQAVEIVIKNRR
ASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPARDAE
>Mature_768_residues
AKAPYSAQAQALPHRMSKLLTEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHITNWAGRVGAWTADIILLLFGLS
AYWLIVPLARRIAVNYRRITRHEAVPDEPERPIGWLTEILAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGAM
SHAFGFTGGTLLLLIALAIGLSLYFRFSWLSVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREGKVEEERVRIED
HEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPAVSLLDPEPKAQEAISADTLEFTSRLIEKKLKDFGVEASVVA
AYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNYMALELPNQRRQTVHLSEIIGSEVYAAASSA
LTLSLGKDIGGKPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVYEGIPHLLCPVV
TDMRQAGNALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKLPNPFSLTPEDPEPLGRLPNIVVVIDELADLM
MVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLYL
APGTGLPVRVHGAFVADDEVHRVVEKLKEQGEPNYIEGLLEGGTADGDEGSAGAGTGEGGDESDPLYDQAVEIVIKNRRA
SISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPARDAE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=494, Percent_Identity=63.7651821862348, Blast_Score=617, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83597; Mature: 83466

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPYSAQAQALPHRMSKLLTEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
NWAGRVGAWTADIILLLFGLSAYWLIVPLARRIAVNYRRITRHEAVPDEPERPIGWLTEI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGAMSHAFGFTGGTLLLLIALAI
HHHHHHHHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLSLYFRFSWLSVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREGKVEEERVRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEC
DHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPAVSLLDPEPKAQEAISADTLE
CCCCEEEECCCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHH
FTSRLIEKKLKDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSI
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEE
RVVETIPGKNYMALELPNQRRQTVHLSEIIGSEVYAAASSALTLSLGKDIGGKPVCADLA
EEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVYEGIPHLLCPV
HCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCHHHHHHH
VTDMRQAGNALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKLPNPFSLTPED
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
PEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITG
CHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
LIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLYLAPGTGLPVRVHGAFVADDE
HHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEEECEEECCHH
VHRVVEKLKEQGEPNYIEGLLEGGTADGDEGSAGAGTGEGGDESDPLYDQAVEIVIKNRR
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
ASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPARDAE
HHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure 
AKAPYSAQAQALPHRMSKLLTEIRWILQVALCAFLVMALLSYSRRDPSWTHAAQVDHIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
NWAGRVGAWTADIILLLFGLSAYWLIVPLARRIAVNYRRITRHEAVPDEPERPIGWLTEI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LAFVLVVLACDGIEALRMWSLKVQLPRAPGGVVGEAVAGAMSHAFGFTGGTLLLLIALAI
HHHHHHHHHCCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLSLYFRFSWLSVAERVGGAILSAVNVAKLRREAERDRKLGEAAAVRREGKVEEERVRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEC
DHEPVTIVPPVVTPAKSERVERERQVPLFTDLPGDSTLPAVSLLDPEPKAQEAISADTLE
CCCCEEEECCCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHH
FTSRLIEKKLKDFGVEASVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSI
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEE
RVVETIPGKNYMALELPNQRRQTVHLSEIIGSEVYAAASSALTLSLGKDIGGKPVCADLA
EEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KMPHLLVAGTTGSGKSVGINAMILSLLYKATAEQVRLILIDPKMLEMSVYEGIPHLLCPV
HCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCHHHHHHH
VTDMRQAGNALNWTVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKLPNPFSLTPED
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
PEPLGRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITG
CHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
LIKANVPTRIAFQVSSKIDSRTILDQMGAESLLGMGDMLYLAPGTGLPVRVHGAFVADDE
HHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEEECEEECCHH
VHRVVEKLKEQGEPNYIEGLLEGGTADGDEGSAGAGTGEGGDESDPLYDQAVEIVIKNRR
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
ASISLVQRHLRIGYNRAARLLEQMEQSGLVSAMSSSGNREILVPARDAE
HHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]