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The map label for this gene is trxB [H]

Identifier: 78065549

GI number: 78065549

Start: 1004174

End: 1005214

Strand: Reverse

Name: trxB [H]

Synonym: Bcep18194_A4077

Alternate gene names: 78065549

Gene position: 1005214-1004174 (Counterclockwise)

Preceding gene: 78065553

Following gene: 78065548

Centisome position: 27.21

GC content: 65.61

Gene sequence:

>1041_bases
ATGACGGCATCCCGGTCACCCCGGATCGTACGGCGAGCCCTACCCCGCCCGCCGCGGCCGCCTTTTACGGATTCGCACAT
GTCCACGCCCAAACACGCCAAAGTCCTGATTCTCGGTTCCGGCCCCGCCGGCTACACGGCTGCCGTATACGCGGCACGCG
CCAACCTGTCCCCGGTGCTGATCACCGGCATCGCGCAGGGCGGCCAGCTGATGACCACGACCGACGTCGAAAACTGGCCG
GCAGACGCGAAAGGCGTGCAGGGTCCGGAGCTGATGGCCCGCTTCCTCGAGCACGCCGAGCGCTTCAACACCGAAATCAT
CTTCGACCACATCCACACCGCGAAGCTGCACGAGCAGCCGATCCGCCTGATCGGCGACTCGGGCGAATACACGTGCGACT
CGCTGATCATCGCGACCGGCGCGTCCGCGCAGTATCTCGGCCTGCCGTCCGAAGAATTGTTCATGGGCAAGGGCGTGTCG
GCCTGCGCGACCTGCGACGGCTTCTTCTATCGCGGCCAGGAAGTCGCGGTGATCGGCGGCGGCAACACGGCCGTCGAGGA
AGCGCTCTACCTCACTGGCATCGCGAAGAAGGTCACGGTGATCCACCGTCGCGACAAGTTCCGCGCGGAGCCGATCCTGA
TCGACCGCCTGCTGGAGAAGGAAAAGGAAGGCGCCGTCGTGATCAAGTGGGATCACGTGCTCGACGAAGTCACCGGCGAA
GATTCGGGCGTCACGGGCCTGCGCATCAAGAACGTGAAGACCGGCGCGACGGAAGATCTCGCCGTGCAAGGCGTGTTCGT
CGCGATCGGCCACAAGCCGAACACCGACCTGTTCCAGGGTCAGCTCGAGATGAAGGACGGCTACATCCTGACGAAGAGCG
GCCTGCACGGCAACGCGACGTCGACGAGCGTCGCCGGCGTGTTCGCCGCGGGCGACGTGCAGGACAACGTGTACCGCCAG
GCGATCACCAGCGCCGGCACGGGCTGCATGGCCGCGCTCGACGCGCAGCGCTACCTCGAAAGCCTGCACGACAAGAAGTA
A

Upstream 100 bases:

>100_bases
GTGCGCGGCCGTTGCACTGCCCGACACTATCGCCACGATTGAAACTCTCGTTCGGCAACGCAGCAACGGGGCCTTTATAA
TGCGCGTCTGATACCCATCT

Downstream 100 bases:

>100_bases
GCCGCGAGACCTGTCGCGCCGGGCGCTACAATGGCGTCCGCTGCCGCGATGCGGGTCTGGCCGGACAAGCCGCTGCCGCC
GTGCAGCGGCTTTTTTTTGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTASRSPRIVRRALPRPPRPPFTDSHMSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWP
ADAKGVQGPELMARFLEHAERFNTEIIFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYLGLPSEELFMGKGVS
ACATCDGFFYRGQEVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKEKEGAVVIKWDHVLDEVTGE
DSGVTGLRIKNVKTGATEDLAVQGVFVAIGHKPNTDLFQGQLEMKDGYILTKSGLHGNATSTSVAGVFAAGDVQDNVYRQ
AITSAGTGCMAALDAQRYLESLHDKK

Sequences:

>Translated_346_residues
MTASRSPRIVRRALPRPPRPPFTDSHMSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWP
ADAKGVQGPELMARFLEHAERFNTEIIFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYLGLPSEELFMGKGVS
ACATCDGFFYRGQEVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKEKEGAVVIKWDHVLDEVTGE
DSGVTGLRIKNVKTGATEDLAVQGVFVAIGHKPNTDLFQGQLEMKDGYILTKSGLHGNATSTSVAGVFAAGDVQDNVYRQ
AITSAGTGCMAALDAQRYLESLHDKK
>Mature_345_residues
TASRSPRIVRRALPRPPRPPFTDSHMSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPA
DAKGVQGPELMARFLEHAERFNTEIIFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYLGLPSEELFMGKGVSA
CATCDGFFYRGQEVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKEKEGAVVIKWDHVLDEVTGED
SGVTGLRIKNVKTGATEDLAVQGVFVAIGHKPNTDLFQGQLEMKDGYILTKSGLHGNATSTSVAGVFAAGDVQDNVYRQA
ITSAGTGCMAALDAQRYLESLHDKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=67.601246105919, Blast_Score=453, Evalue=1e-129,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=35.2564102564103, Blast_Score=140, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321898, Length=340, Percent_Identity=45.8823529411765, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=47.2222222222222, Blast_Score=271, Evalue=1e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 37185; Mature: 37054

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASRSPRIVRRALPRPPRPPFTDSHMSTPKHAKVLILGSGPAGYTAAVYAARANLSPVL
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEHHCCCCEEE
ITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFLEHAERFNTEIIFDHIHTAKLHEQP
EEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCC
IRLIGDSGEYTCDSLIIATGASAQYLGLPSEELFMGKGVSACATCDGFFYRGQEVAVIGG
CEEECCCCCCEECEEEEEECCCCEEECCCCHHHHHCCCCCHHHCCCCCEECCCEEEEEEC
GNTAVEEALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKEKEGAVVIKWDHVLDEVTGE
CCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHCCC
DSGVTGLRIKNVKTGATEDLAVQGVFVAIGHKPNTDLFQGQLEMKDGYILTKSGLHGNAT
CCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHCCEEEECCCEEEEECCCCCCCC
STSVAGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK
CCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TASRSPRIVRRALPRPPRPPFTDSHMSTPKHAKVLILGSGPAGYTAAVYAARANLSPVL
CCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEHHCCCCEEE
ITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFLEHAERFNTEIIFDHIHTAKLHEQP
EEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCC
IRLIGDSGEYTCDSLIIATGASAQYLGLPSEELFMGKGVSACATCDGFFYRGQEVAVIGG
CEEECCCCCCEECEEEEEECCCCEEECCCCHHHHHCCCCCHHHCCCCCEECCCEEEEEEC
GNTAVEEALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKEKEGAVVIKWDHVLDEVTGE
CCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHCCC
DSGVTGLRIKNVKTGATEDLAVQGVFVAIGHKPNTDLFQGQLEMKDGYILTKSGLHGNAT
CCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHCCEEEECCCEEEEECCCCCCCC
STSVAGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK
CCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]