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The map label for this gene is ribE [H]

Identifier: 78065535

GI number: 78065535

Start: 988305

End: 988940

Strand: Reverse

Name: ribE [H]

Synonym: Bcep18194_A4063

Alternate gene names: 78065535

Gene position: 988940-988305 (Counterclockwise)

Preceding gene: 78065536

Following gene: 78065533

Centisome position: 26.77

GC content: 64.31

Gene sequence:

>636_bases
ATGTTTAGCGGCATTGTCGCGGCCGTCGGCCGTATCGAATCGATCCAGCCGCTCGGCGCGTCGGCCGATGCGGGTGTGCG
CCTCACCGTGCTGGCCGGCGGGCTCGACCTCGCCGATGTGGCGCTCGGCGACAGCATCGCGATCCAGGGCGCATGCATGA
CGGTGATCGAAAAATCCGACGCCGCGTTCGACGTCGACGTGTCGCGCGAAAGCCTGAACCGCACAGTCGGCCTCGCAACA
CCCGGCGACGTGAACCTCGAGAAGGCATTGCGCGCGCACGACCGCCTCGGCGGGCACATCGTGTCGGGTCATGTGGACGG
ACTCGGCACGGTGTCGCGGTTCGAGCCCGTCGGCGAATCGCACGAACTGCGCATCGTCGCGCCGCGCGAACTCGGCCGCT
ATCTCGCGTACAAGGGGTCGATCACGGTCAACGGCGTGAGCCTGACCGTCAACACGATCGACGATCGCGCGGACGGCTGC
GAGTTCTCGATCAACCTGATTCCGCATACGGTCGAGGTCACGACGCTGCGGCACGTGAAAGCCGGCGACAAGGTCAATCT
CAAAGTCGACATGATCGCGCGGTATGTCGAACGAATGATGAGCGCGGCTAAGGACAGCCATATGACATCGAAATAG

Upstream 100 bases:

>100_bases
CGCGGTTGTCGTTCCACGGGTTCGAGCGGGTCGGCGACGATCTGCGAATCCTCGCGCGCTTCGCGCCGCCCGACGCCGCT
CACTGAACGGGAGCGTCACG

Downstream 100 bases:

>100_bases
TTAGTATTTTAGTGATTCAACTGTGCCACCAACTCACTAAAACTAAAACTCGTCACGCCGACCCACCATCCTTCAGTGGT
CCATCCAAAGCTACTGCAAC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFSGIVAAVGRIESIQPLGASADAGVRLTVLAGGLDLADVALGDSIAIQGACMTVIEKSDAAFDVDVSRESLNRTVGLAT
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFEPVGESHELRIVAPRELGRYLAYKGSITVNGVSLTVNTIDDRADGC
EFSINLIPHTVEVTTLRHVKAGDKVNLKVDMIARYVERMMSAAKDSHMTSK

Sequences:

>Translated_211_residues
MFSGIVAAVGRIESIQPLGASADAGVRLTVLAGGLDLADVALGDSIAIQGACMTVIEKSDAAFDVDVSRESLNRTVGLAT
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFEPVGESHELRIVAPRELGRYLAYKGSITVNGVSLTVNTIDDRADGC
EFSINLIPHTVEVTTLRHVKAGDKVNLKVDMIARYVERMMSAAKDSHMTSK
>Mature_211_residues
MFSGIVAAVGRIESIQPLGASADAGVRLTVLAGGLDLADVALGDSIAIQGACMTVIEKSDAAFDVDVSRESLNRTVGLAT
PGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFEPVGESHELRIVAPRELGRYLAYKGSITVNGVSLTVNTIDDRADGC
EFSINLIPHTVEVTTLRHVKAGDKVNLKVDMIARYVERMMSAAKDSHMTSK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=214, Percent_Identity=31.3084112149533, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=219, Percent_Identity=34.2465753424658, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22319; Mature: 22319

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIVAAVGRIESIQPLGASADAGVRLTVLAGGLDLADVALGDSIAIQGACMTVIEKSD
CCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEHHHCCCCEEECCEEEEEEECCC
AAFDVDVSRESLNRTVGLATPGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFEPVGES
CEEEEECCHHHHCCEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHCCCCCCC
HELRIVAPRELGRYLAYKGSITVNGVSLTVNTIDDRADGCEFSINLIPHTVEVTTLRHVK
CCEEEECHHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEEECCCEEEEEEEEEEC
AGDKVNLKVDMIARYVERMMSAAKDSHMTSK
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFSGIVAAVGRIESIQPLGASADAGVRLTVLAGGLDLADVALGDSIAIQGACMTVIEKSD
CCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEHHHCCCCEEECCEEEEEEECCC
AAFDVDVSRESLNRTVGLATPGDVNLEKALRAHDRLGGHIVSGHVDGLGTVSRFEPVGES
CEEEEECCHHHHCCEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHCCCCCCC
HELRIVAPRELGRYLAYKGSITVNGVSLTVNTIDDRADGCEFSINLIPHTVEVTTLRHVK
CCEEEECHHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEEECCCEEEEEEEEEEC
AGDKVNLKVDMIARYVERMMSAAKDSHMTSK
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]