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The map label for this gene is uppP

Identifier: 78065493

GI number: 78065493

Start: 945609

End: 946439

Strand: Direct

Name: uppP

Synonym: Bcep18194_A4021

Alternate gene names: 78065493

Gene position: 945609-946439 (Clockwise)

Preceding gene: 78065492

Following gene: 78065495

Centisome position: 25.6

GC content: 64.62

Gene sequence:

>831_bases
ATGGACTGGATCCTGATCTGCAAGGCTTTGATCCTCGGCGTCGTCGAGGGGCTGACGGAATTCCTGCCGGTATCGAGTAC
CGGTCACCTGATCGTCGCGGGCAGCTTCCTGAATTTCAACGATTCACATGCGAAGACGTTCGACGTCGTGATCCAGTTCG
GTGCGATCCTCGCGGTCTGCTGGGAATACCGGCAACGGATCGCGTCCATCGTGTCCGGGCTGCCGAGCCGGCCCGATGCG
CGGCGCTTCACGCTGAACGTCGTGATCGCGACGATTCCCGCGATCGCACTCGGCCTTCTGTTCGAGAAGAAGATCAAGGC
CGTGCTGTTCTCGCCGGTGCCCGTCGCGTTCGCGCTCGTCGTGGGCGGCGCGATCATCCTGTGGGCCGAGGCGCGGCAGC
GCGAGCGCCGCGAGCCGCCGCGCGTGATGTCGGTCGATGAACTGACGCCGCTCGACGCGCTCAAGGTCGGTATCGCGCAG
TGCTTCGCGCTGATTCCCGGCATGTCGCGCTCGGGTTCGACGATCATCGGCGGGATGCTGTTCGGCCTCGACCGGCGCGT
CGCCACCGAATTCTCGTTCTTCCTCGCGATCCCGATCATCTTCGGCGCGACGCTCTATGAAACCGTGAAGGACTGGCAGG
CGTTCACCGTCGATTCGCTCGGCCTGTTCGTGCTGGGCGCCGTCGCGGCATTCGTCAGCGCGTTCGTGTGCGTGCGCTGG
CTGCTGCGCTATGTCGCGTCGCACGATTTCACGGTGTTCGCGTGGTACCGGATCGCATTCGGGCTGTTCGTGCTGCTGGT
CGGGTACAGCGGCTGGCTGAACTGGGCGTGA

Upstream 100 bases:

>100_bases
GGCGATCGTCGAAAAGTGACGACGAACCGCGCTCGGCCGGAGGGGGGCCGCGCGTGGAAGAGTGGCCCATTCATTCGACC
ATTTCGGAGTTGGGCCACGG

Downstream 100 bases:

>100_bases
CGCGAACCCGAAGGCGGGCGCGCCTCGCATGAAAAAAGCCCGATCGGCATAGGCCGGTCGGGCTTTTTCTTGTCCGGAGC
GGAGCGACGTGCGCTGCCGC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1 [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDWILICKALILGVVEGLTEFLPVSSTGHLIVAGSFLNFNDSHAKTFDVVIQFGAILAVCWEYRQRIASIVSGLPSRPDA
RRFTLNVVIATIPAIALGLLFEKKIKAVLFSPVPVAFALVVGGAIILWAEARQRERREPPRVMSVDELTPLDALKVGIAQ
CFALIPGMSRSGSTIIGGMLFGLDRRVATEFSFFLAIPIIFGATLYETVKDWQAFTVDSLGLFVLGAVAAFVSAFVCVRW
LLRYVASHDFTVFAWYRIAFGLFVLLVGYSGWLNWA

Sequences:

>Translated_276_residues
MDWILICKALILGVVEGLTEFLPVSSTGHLIVAGSFLNFNDSHAKTFDVVIQFGAILAVCWEYRQRIASIVSGLPSRPDA
RRFTLNVVIATIPAIALGLLFEKKIKAVLFSPVPVAFALVVGGAIILWAEARQRERREPPRVMSVDELTPLDALKVGIAQ
CFALIPGMSRSGSTIIGGMLFGLDRRVATEFSFFLAIPIIFGATLYETVKDWQAFTVDSLGLFVLGAVAAFVSAFVCVRW
LLRYVASHDFTVFAWYRIAFGLFVLLVGYSGWLNWA
>Mature_276_residues
MDWILICKALILGVVEGLTEFLPVSSTGHLIVAGSFLNFNDSHAKTFDVVIQFGAILAVCWEYRQRIASIVSGLPSRPDA
RRFTLNVVIATIPAIALGLLFEKKIKAVLFSPVPVAFALVVGGAIILWAEARQRERREPPRVMSVDELTPLDALKVGIAQ
CFALIPGMSRSGSTIIGGMLFGLDRRVATEFSFFLAIPIIFGATLYETVKDWQAFTVDSLGLFVLGAVAAFVSAFVCVRW
LLRYVASHDFTVFAWYRIAFGLFVLLVGYSGWLNWA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin [H]

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family [H]

Homologues:

Organism=Escherichia coli, GI1789437, Length=256, Percent_Identity=44.921875, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003824 [H]

Pfam domain/function: PF02673 BacA [H]

EC number: =3.6.1.27 [H]

Molecular weight: Translated: 30354; Mature: 30354

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWILICKALILGVVEGLTEFLPVSSTGHLIVAGSFLNFNDSHAKTFDVVIQFGAILAVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
WEYRQRIASIVSGLPSRPDARRFTLNVVIATIPAIALGLLFEKKIKAVLFSPVPVAFALV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VGGAIILWAEARQRERREPPRVMSVDELTPLDALKVGIAQCFALIPGMSRSGSTIIGGML
HCCHHEEEHHHHHHHCCCCCCEECHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FGLDRRVATEFSFFLAIPIIFGATLYETVKDWQAFTVDSLGLFVLGAVAAFVSAFVCVRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRYVASHDFTVFAWYRIAFGLFVLLVGYSGWLNWA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDWILICKALILGVVEGLTEFLPVSSTGHLIVAGSFLNFNDSHAKTFDVVIQFGAILAVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
WEYRQRIASIVSGLPSRPDARRFTLNVVIATIPAIALGLLFEKKIKAVLFSPVPVAFALV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VGGAIILWAEARQRERREPPRVMSVDELTPLDALKVGIAQCFALIPGMSRSGSTIIGGML
HCCHHEEEHHHHHHHCCCCCCEECHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FGLDRRVATEFSFFLAIPIIFGATLYETVKDWQAFTVDSLGLFVLGAVAAFVSAFVCVRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRYVASHDFTVFAWYRIAFGLFVLLVGYSGWLNWA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA