Definition Burkholderia sp. 383 chromosome 1, complete genome.
Accession NC_007510
Length 3,694,126

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The map label for this gene is abcA [H]

Identifier: 78065450

GI number: 78065450

Start: 899897

End: 901204

Strand: Reverse

Name: abcA [H]

Synonym: Bcep18194_A3976

Alternate gene names: 78065450

Gene position: 901204-899897 (Counterclockwise)

Preceding gene: 78065451

Following gene: 78065449

Centisome position: 24.4

GC content: 61.16

Gene sequence:

>1308_bases
ATGCAAACTCGCGAGCCTGAACCTACAAGCCAAACGGAACAGCTGCTCGTCAACGTCGAGCACCTCTCCAAGTGCTTCCG
TATCTACGACAAACCGGCAGACCGGCTGCGGCACTCGCTCGCGACTCGCATCAAGCTCCCCGGGAGCAATTCCCGGCAAT
ACGGTCGTGATTTTTGGGCGCTGCACGACGTCTCGTTCCCCGTCCGGCGGGGCGAGACCATCGGAATCATTGGCAGAAAC
GGTTCCGGAAAGTCGACGTTGCTGCAAATCATTGCCGGCACGCTGTCGCCGAGCGACGGCTCGGTCACGGTCAACGGCCG
AATCTCCGCACTGCTGGAACTCGGCGCCGGGTTCAATCCGGAATTCAGCGGCCGCGAGAACGTGATGCTGTCTGCACGGA
TCATGGGCATCACGTCGGAAGAAATCCGCGCGCGTTTTCACGAAATCGAAGCGTTCGCCGACATCGGCGAATTCATCGAC
CAGCCCGTCAAGACCTACTCGTCGGGCATGTACGTCCGGCTCGCATTCGCGGTAGCCATTCACGTCTCCCCCGATATCCT
GGTGGTCGACGAGGCACTTGCGGTCGGCGATACCGCGTTTCAGACCAAATGCCTGACGCGGATCCGGAAGATGCAGAAGG
AAGGCGTCACGATCCTGCTGGTCACACACTCCACCAACACCCTCGTCGAGTACTGCGACCGGGCCATCTACCTGAAGCGG
GGCCGGCTGGTAAAGGACGGTCCGTGCCGCGACGTGGTCAAGCTCTATGCGAACGACCTCGTCGACGAAGAAGGCGGGAG
CGCGATCGACATCGAGGTGCCGACACAGCACACCGACACCGCTTCCCCCGCCAGCTCGGCGGTAAGCGATGCCATGACGG
CCTTGTCGGACCGGACGTCGATTCTCGACGTGAAGATCGAGGATGCGAACGGCAAGGAACGCACGACCTTCTCGTTCAAT
GAAGCGTTCCGCGTCGTCGTATCGATCAGCGTGTCCGAGCCGAACCCGAAGCCTTGCTTCGGACTTCAGATCAAAAGCAT
CGACGATATCGTGCTGTGGAGCGCGACCACCCAGCACATGAATATTGCGCTGCCGCCCCTGTCCGCCGGAAAGTACCAGT
TCACCTGGAAGATGCGCGCGAGCTTCTCTGGCAACCGCTATGTGCTGGCGGTCGGCGTCGGCGATATCGCCTCCGGCGAA
TACAAGCGGCACGCGCGCCTGCCCTATGGTGGCCACATCGACGTGCTTCCGGAAAACAACAGTGGATCGGGGTGGCTCGC
GCCGTGTCCGGTGTTCGAGTTCGAATGA

Upstream 100 bases:

>100_bases
GGTGGCCGCGAGGCGAGTCAGCATCCGACCCCTGAGTCTACTGTGCGATCGTCTTTTTTCCGCCTGCGCTGAACACGTGA
AAGCTAACTCGCTCCCCCTC

Downstream 100 bases:

>100_bases
TGACGGAGAACGACACCATGCAAGCGCGCAGCATCAAGGTCGTCGCGGTCGGCTATTACGGCGCACCCAACGTCGGCGAC
GAATTGTTGCTGGGCCTGCT

Product: ABC polysaccharide/polyol phosphate export pump, ATPase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MQTREPEPTSQTEQLLVNVEHLSKCFRIYDKPADRLRHSLATRIKLPGSNSRQYGRDFWALHDVSFPVRRGETIGIIGRN
GSGKSTLLQIIAGTLSPSDGSVTVNGRISALLELGAGFNPEFSGRENVMLSARIMGITSEEIRARFHEIEAFADIGEFID
QPVKTYSSGMYVRLAFAVAIHVSPDILVVDEALAVGDTAFQTKCLTRIRKMQKEGVTILLVTHSTNTLVEYCDRAIYLKR
GRLVKDGPCRDVVKLYANDLVDEEGGSAIDIEVPTQHTDTASPASSAVSDAMTALSDRTSILDVKIEDANGKERTTFSFN
EAFRVVVSISVSEPNPKPCFGLQIKSIDDIVLWSATTQHMNIALPPLSAGKYQFTWKMRASFSGNRYVLAVGVGDIASGE
YKRHARLPYGGHIDVLPENNSGSGWLAPCPVFEFE

Sequences:

>Translated_435_residues
MQTREPEPTSQTEQLLVNVEHLSKCFRIYDKPADRLRHSLATRIKLPGSNSRQYGRDFWALHDVSFPVRRGETIGIIGRN
GSGKSTLLQIIAGTLSPSDGSVTVNGRISALLELGAGFNPEFSGRENVMLSARIMGITSEEIRARFHEIEAFADIGEFID
QPVKTYSSGMYVRLAFAVAIHVSPDILVVDEALAVGDTAFQTKCLTRIRKMQKEGVTILLVTHSTNTLVEYCDRAIYLKR
GRLVKDGPCRDVVKLYANDLVDEEGGSAIDIEVPTQHTDTASPASSAVSDAMTALSDRTSILDVKIEDANGKERTTFSFN
EAFRVVVSISVSEPNPKPCFGLQIKSIDDIVLWSATTQHMNIALPPLSAGKYQFTWKMRASFSGNRYVLAVGVGDIASGE
YKRHARLPYGGHIDVLPENNSGSGWLAPCPVFEFE
>Mature_435_residues
MQTREPEPTSQTEQLLVNVEHLSKCFRIYDKPADRLRHSLATRIKLPGSNSRQYGRDFWALHDVSFPVRRGETIGIIGRN
GSGKSTLLQIIAGTLSPSDGSVTVNGRISALLELGAGFNPEFSGRENVMLSARIMGITSEEIRARFHEIEAFADIGEFID
QPVKTYSSGMYVRLAFAVAIHVSPDILVVDEALAVGDTAFQTKCLTRIRKMQKEGVTILLVTHSTNTLVEYCDRAIYLKR
GRLVKDGPCRDVVKLYANDLVDEEGGSAIDIEVPTQHTDTASPASSAVSDAMTALSDRTSILDVKIEDANGKERTTFSFN
EAFRVVVSISVSEPNPKPCFGLQIKSIDDIVLWSATTQHMNIALPPLSAGKYQFTWKMRASFSGNRYVLAVGVGDIASGE
YKRHARLPYGGHIDVLPENNSGSGWLAPCPVFEFE

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=281, Percent_Identity=26.3345195729537, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI47078218, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI45446740, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI27436953, Length=197, Percent_Identity=29.9492385786802, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI6005701, Length=212, Percent_Identity=27.8301886792453, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI27477115, Length=200, Percent_Identity=29, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI105990541, Length=219, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI89111135, Length=205, Percent_Identity=25.8536585365854, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI150417984, Length=223, Percent_Identity=23.7668161434978, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI27262624, Length=216, Percent_Identity=26.8518518518519, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI27262626, Length=216, Percent_Identity=26.8518518518519, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI30795238, Length=196, Percent_Identity=22.9591836734694, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI27881501, Length=205, Percent_Identity=22.4390243902439, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21729876, Length=199, Percent_Identity=26.6331658291457, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21729873, Length=199, Percent_Identity=26.6331658291457, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI15149474, Length=199, Percent_Identity=26.6331658291457, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI116734710, Length=197, Percent_Identity=25.8883248730964, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI157502201, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI157502203, Length=269, Percent_Identity=26.7657992565056, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081709, Length=206, Percent_Identity=27.1844660194175, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787758, Length=202, Percent_Identity=29.7029702970297, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081782, Length=222, Percent_Identity=31.0810810810811, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=28.310502283105, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789891, Length=205, Percent_Identity=26.8292682926829, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786398, Length=254, Percent_Identity=26.7716535433071, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081791, Length=200, Percent_Identity=26.5, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI48995001, Length=227, Percent_Identity=26.8722466960352, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI48994943, Length=210, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789032, Length=224, Percent_Identity=26.3392857142857, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787370, Length=226, Percent_Identity=24.7787610619469, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788225, Length=212, Percent_Identity=29.7169811320755, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786703, Length=211, Percent_Identity=31.2796208530806, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787712, Length=214, Percent_Identity=27.1028037383178, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787089, Length=223, Percent_Identity=25.1121076233184, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790467, Length=230, Percent_Identity=26.5217391304348, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788210, Length=215, Percent_Identity=30.2325581395349, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788506, Length=215, Percent_Identity=26.046511627907, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786253, Length=224, Percent_Identity=26.7857142857143, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081834, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=25.2336448598131, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693107, Length=242, Percent_Identity=25.2066115702479, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788897, Length=203, Percent_Identity=25.1231527093596, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790525, Length=222, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788165, Length=187, Percent_Identity=26.7379679144385, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786319, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789593, Length=208, Percent_Identity=24.0384615384615, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786872, Length=214, Percent_Identity=27.5700934579439, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=227, Percent_Identity=26.8722466960352, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115533608, Length=207, Percent_Identity=27.0531400966184, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71983510, Length=221, Percent_Identity=26.2443438914027, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=221, Percent_Identity=26.2443438914027, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=221, Percent_Identity=26.2443438914027, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71992066, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25146765, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71992070, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI86564969, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=25.3456221198157, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569081, Length=208, Percent_Identity=27.4038461538462, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321720, Length=190, Percent_Identity=30, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24666092, Length=237, Percent_Identity=24.4725738396624, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648314, Length=207, Percent_Identity=27.0531400966184, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643674, Length=236, Percent_Identity=23.728813559322, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161077321, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI85816269, Length=312, Percent_Identity=26.2820512820513, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580553, Length=312, Percent_Identity=26.2820512820513, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85724864, Length=312, Percent_Identity=26.2820512820513, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580555, Length=312, Percent_Identity=26.2820512820513, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=198, Percent_Identity=23.7373737373737, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574259, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=198, Percent_Identity=23.7373737373737, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573571, Length=237, Percent_Identity=24.4725738396624, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573573, Length=237, Percent_Identity=24.4725738396624, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62484234, Length=270, Percent_Identity=24.8148148148148, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574533, Length=231, Percent_Identity=24.6753246753247, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI85726357, Length=217, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 47800; Mature: 47800

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MQTREPEPTSQTEQLLVNVEHLSKCFRIYDKPADRLRHSLATRIKLPGSNSRQYGRDFWA
CCCCCCCCCCCHHHHEEEHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCCCEEE
LHDVSFPVRRGETIGIIGRNGSGKSTLLQIIAGTLSPSDGSVTVNGRISALLELGAGFNP
EECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCHHEEHHHHCCCCCC
EFSGRENVMLSARIMGITSEEIRARFHEIEAFADIGEFIDQPVKTYSSGMYVRLAFAVAI
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEE
HVSPDILVVDEALAVGDTAFQTKCLTRIRKMQKEGVTILLVTHSTNTLVEYCDRAIYLKR
ECCCCEEEEECHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCEEEEEC
GRLVKDGPCRDVVKLYANDLVDEEGGSAIDIEVPTQHTDTASPASSAVSDAMTALSDRTS
CCEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE
ILDVKIEDANGKERTTFSFNEAFRVVVSISVSEPNPKPCFGLQIKSIDDIVLWSATTQHM
EEEEEEECCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCE
NIALPPLSAGKYQFTWKMRASFSGNRYVLAVGVGDIASGEYKRHARLPYGGHIDVLPENN
EEECCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHCCCCCCCEEEEEECCC
SGSGWLAPCPVFEFE
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTREPEPTSQTEQLLVNVEHLSKCFRIYDKPADRLRHSLATRIKLPGSNSRQYGRDFWA
CCCCCCCCCCCHHHHEEEHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCCCEEE
LHDVSFPVRRGETIGIIGRNGSGKSTLLQIIAGTLSPSDGSVTVNGRISALLELGAGFNP
EECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCHHEEHHHHCCCCCC
EFSGRENVMLSARIMGITSEEIRARFHEIEAFADIGEFIDQPVKTYSSGMYVRLAFAVAI
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEE
HVSPDILVVDEALAVGDTAFQTKCLTRIRKMQKEGVTILLVTHSTNTLVEYCDRAIYLKR
ECCCCEEEEECHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCEEEEEC
GRLVKDGPCRDVVKLYANDLVDEEGGSAIDIEVPTQHTDTASPASSAVSDAMTALSDRTS
CCEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE
ILDVKIEDANGKERTTFSFNEAFRVVVSISVSEPNPKPCFGLQIKSIDDIVLWSATTQHM
EEEEEEECCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCE
NIALPPLSAGKYQFTWKMRASFSGNRYVLAVGVGDIASGEYKRHARLPYGGHIDVLPENN
EEECCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHCCCCCCCEEEEEECCC
SGSGWLAPCPVFEFE
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]