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The map label for this gene is dtd [H]

Identifier: 78065246

GI number: 78065246

Start: 665639

End: 666097

Strand: Direct

Name: dtd [H]

Synonym: Bcep18194_A3770

Alternate gene names: 78065246

Gene position: 665639-666097 (Clockwise)

Preceding gene: 78065245

Following gene: 78065247

Centisome position: 18.02

GC content: 70.37

Gene sequence:

>459_bases
ATGATCGCGCTGATCCAGCGCGTGAAGCGCGCCGACGTGCGCGTCGGCGACCGTACGACCGGCGAGATCGGCGCGGGCCT
GCTCGCGCTGGTCTGCGCGGAGCGCGGCGACACCGACGCAGCGGCCGACAAGCTGCTCGCGAAGATGCTCGGCTATCGCG
TGTTCAGCGACGCCGCCGGCAAGATGAACCTGCCGGTATCGAATATCGACGGTGAGGGCCGCGCGGGCGGCCTGCTGCTC
GTGTCGCAGTTCACGCTGGCGGCCGATACCAACAGCGGGCTGCGTCCGAGCTTTACGCCGGCCGCGCCGCCCGACGAAGG
CGCGCGGCTGTTCGACTATTTCGTCGCGGCCGCGCGTGCGCGCCATCCGGTCGTCGAGACGGGCGAGTTCGGCGCCGACA
TGCAGGTGTCGCTCGTCAACGACGGCCCCGTGACATTCTGGCTGCAAGTGCGGCCCTGA

Upstream 100 bases:

>100_bases
TCGATGGCGCGACCGTGTCGGACAAGGGCCTGAAGGTCGAAGCCGGCGAGTTCGTCGTGCAGGTCGGCAAGCGCCGCTTC
GCGCGCGTCACGCTGACCGC

Downstream 100 bases:

>100_bases
TTCTTCCCCGGAGACGCGCCGCGATGGCCACCACGCAGATTCTTTTCATCCGCCATGGCGAGACGGCCTGGAATCGCATC
AAGCGCATCCAGGGTCATAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MIALIQRVKRADVRVGDRTTGEIGAGLLALVCAERGDTDAAADKLLAKMLGYRVFSDAAGKMNLPVSNIDGEGRAGGLLL
VSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARARHPVVETGEFGADMQVSLVNDGPVTFWLQVRP

Sequences:

>Translated_152_residues
MIALIQRVKRADVRVGDRTTGEIGAGLLALVCAERGDTDAAADKLLAKMLGYRVFSDAAGKMNLPVSNIDGEGRAGGLLL
VSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARARHPVVETGEFGADMQVSLVNDGPVTFWLQVRP
>Mature_152_residues
MIALIQRVKRADVRVGDRTTGEIGAGLLALVCAERGDTDAAADKLLAKMLGYRVFSDAAGKMNLPVSNIDGEGRAGGLLL
VSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARARHPVVETGEFGADMQVSLVNDGPVTFWLQVRP

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=36.4238410596026, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790320, Length=150, Percent_Identity=58.6666666666667, Blast_Score=173, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=37.1621621621622, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=37.3333333333333, Blast_Score=84, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=36.4238410596026, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16074; Mature: 16074

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVKRADVRVGDRTTGEIGAGLLALVCAERGDTDAAADKLLAKMLGYRVFSDAAG
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
KMNLPVSNIDGEGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARA
EECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RHPVVETGEFGADMQVSLVNDGPVTFWLQVRP
CCCCCCCCCCCCCEEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MIALIQRVKRADVRVGDRTTGEIGAGLLALVCAERGDTDAAADKLLAKMLGYRVFSDAAG
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
KMNLPVSNIDGEGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARA
EECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RHPVVETGEFGADMQVSLVNDGPVTFWLQVRP
CCCCCCCCCCCCCEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA