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The map label for this gene is trpB [H]

Identifier: 78048425

GI number: 78048425

Start: 3261238

End: 3262455

Strand: Reverse

Name: trpB [H]

Synonym: XCV2869

Alternate gene names: 78048425

Gene position: 3262455-3261238 (Counterclockwise)

Preceding gene: 78048427

Following gene: 78048424

Centisome position: 63.0

GC content: 64.78

Gene sequence:

>1218_bases
ATGTCGGCCCAGCCCATCAGTGACTTTTACGCCTATCCGGATGCTGCCGGTCACTTCGGCAAGTTCGGTGGCCGTTTCGT
CGCCGAAACCTTGATCGGCCCGCTGCAGGAATTGTCCGCCGCCTACGATCAGGCACGGCAGGACCCGAGTTTCATTGCCG
AATACGACAAGGACCTCAAGCATTACGTCGGCCGGCCCAGCCCGATCTACCACGCCGAGCGGCTCAGCCGTGAAGTGGGT
GGGGCGCAGATCCTGCTCAAGCGCGAAGACCTGAACCACACCGGCGCGCACAAGATCAACAACACCATCGGCCAGGCGCT
GTTGGCCAGCCGCATGGGCAAGACCCGCATCATCGCCGAGACCGGCGCCGGCCAGCACGGCGTCGCCAGTGCCACCGTGG
CGGCACGCCTGGGCCTGGAATGCGTGGTCTACATGGGCGCCACCGACATCGAGCGGCAAAAGATCAACGTCTACCGCATG
AAGCTGCTCGGCGCCACGGTGATCCCGGTGACTTCCGGCTCGGCCACGCTCAAGGACGCGCTCAACGAAGCCATGCGCGA
CTGGGTGACCAACGTGCGCGACACCTTCTACATCATCGGCACCGTGGCTGGCCCGGACCCATACCCGCGCATGGTGCGCG
ACTTCAATGCGATTGTCGGTCGCGAGGCGCGCGAACAGATGCTGCAGGACTATGGTCGGCTGCCGGATGCGATCAGTGCC
TGCGTGGGTGGCGGCAGCAATGCGATCGGTTTGTTCCATGCCTTCCTCAATGATCCGGGCGTCAAGATCTATGGCGCCGA
AGCGGCCGGCGATGGCATCGCCACCGGCCGCCACGCCGCCTCCATCGCCGCAGGTCGCCCGGGCGTGCTGCACGGCAACC
GCACCTACGTGATCTGCGACGATGACGGCCAGATCACCGAGACCCATTCGATTTCCGCCGGCCTGGATTACCCGGGTGTG
GGCCCGGAGCATTCGTTCCTGTCCGACAGCGGTCGCGCGGTGTACCAGGGCATTACCGACGACGAGGCGATGGCCGCCTT
CCATCTGCTGGCGCATACCGAAGGCATTCTTGCCGCGCTCGAGTCCAGCCATGCGGTGGCGCAGTCGATCAAGCTTGCGC
GCGAGCTGCCCAGGGATGCGCTGGTGTTGTGCAATCTGTCCGGGCGTGGCGATAAGGATGTGCATACCATCGCAGCGCGC
GAGGGGATCGCTCTTTAA

Upstream 100 bases:

>100_bases
GATTCCAGCTCACAGGTTGCGGCAATCTTATCGATTTATTGCGCACCGCGGCTGCGCTAAAGTGATGCCTCTCGTATGAC
GCATCGCTGCAGAGGATTCC

Downstream 100 bases:

>100_bases
AAGTGGTGGCGGCTGACGCTATCCGGATGCAGGGACGCGGCGATGCTCGAAGGAATGCTTCAGTTGGTGGCCGAGGTGCT
GCTGCAGGCCTTGGCCGAGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSAQPISDFYAYPDAAGHFGKFGGRFVAETLIGPLQELSAAYDQARQDPSFIAEYDKDLKHYVGRPSPIYHAERLSREVG
GAQILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRM
KLLGATVIPVTSGSATLKDALNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAIVGREAREQMLQDYGRLPDAISA
CVGGGSNAIGLFHAFLNDPGVKIYGAEAAGDGIATGRHAASIAAGRPGVLHGNRTYVICDDDGQITETHSISAGLDYPGV
GPEHSFLSDSGRAVYQGITDDEAMAAFHLLAHTEGILAALESSHAVAQSIKLARELPRDALVLCNLSGRGDKDVHTIAAR
EGIAL

Sequences:

>Translated_405_residues
MSAQPISDFYAYPDAAGHFGKFGGRFVAETLIGPLQELSAAYDQARQDPSFIAEYDKDLKHYVGRPSPIYHAERLSREVG
GAQILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRM
KLLGATVIPVTSGSATLKDALNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAIVGREAREQMLQDYGRLPDAISA
CVGGGSNAIGLFHAFLNDPGVKIYGAEAAGDGIATGRHAASIAAGRPGVLHGNRTYVICDDDGQITETHSISAGLDYPGV
GPEHSFLSDSGRAVYQGITDDEAMAAFHLLAHTEGILAALESSHAVAQSIKLARELPRDALVLCNLSGRGDKDVHTIAAR
EGIAL
>Mature_404_residues
SAQPISDFYAYPDAAGHFGKFGGRFVAETLIGPLQELSAAYDQARQDPSFIAEYDKDLKHYVGRPSPIYHAERLSREVGG
AQILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRMK
LLGATVIPVTSGSATLKDALNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAIVGREAREQMLQDYGRLPDAISAC
VGGGSNAIGLFHAFLNDPGVKIYGAEAAGDGIATGRHAASIAAGRPGVLHGNRTYVICDDDGQITETHSISAGLDYPGVG
PEHSFLSDSGRAVYQGITDDEAMAAFHLLAHTEGILAALESSHAVAQSIKLARELPRDALVLCNLSGRGDKDVHTIAARE
GIAL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=53.8057742782152, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6321412, Length=381, Percent_Identity=54.3307086614173, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43193; Mature: 43062

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPISDFYAYPDAAGHFGKFGGRFVAETLIGPLQELSAAYDQARQDPSFIAEYDKDLK
CCCCCCHHHHCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HYVGRPSPIYHAERLSREVGGAQILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAE
HHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRMKLLGATVIPVTSGSATLKDA
CCCCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHH
LNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAIVGREAREQMLQDYGRLPDAISA
HHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHH
CVGGGSNAIGLFHAFLNDPGVKIYGAEAAGDGIATGRHAASIAAGRPGVLHGNRTYVICD
HHCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHCCCCCCEEECCEEEEEEC
DDGQITETHSISAGLDYPGVGPEHSFLSDSGRAVYQGITDDEAMAAFHLLAHTEGILAAL
CCCCEEECCCCCCCCCCCCCCCCCCHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
ESSHAVAQSIKLARELPRDALVLCNLSGRGDKDVHTIAAREGIAL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SAQPISDFYAYPDAAGHFGKFGGRFVAETLIGPLQELSAAYDQARQDPSFIAEYDKDLK
CCCCCHHHHCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HYVGRPSPIYHAERLSREVGGAQILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAE
HHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRMKLLGATVIPVTSGSATLKDA
CCCCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHH
LNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAIVGREAREQMLQDYGRLPDAISA
HHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHH
CVGGGSNAIGLFHAFLNDPGVKIYGAEAAGDGIATGRHAASIAAGRPGVLHGNRTYVICD
HHCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHCCCCCCEEECCEEEEEEC
DDGQITETHSISAGLDYPGVGPEHSFLSDSGRAVYQGITDDEAMAAFHLLAHTEGILAAL
CCCCEEECCCCCCCCCCCCCCCCCCHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
ESSHAVAQSIKLARELPRDALVLCNLSGRGDKDVHTIAAREGIAL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]