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The map label for this gene is pcbC [H]

Identifier: 78048418

GI number: 78048418

Start: 3255158

End: 3256096

Strand: Reverse

Name: pcbC [H]

Synonym: XCV2862

Alternate gene names: 78048418

Gene position: 3256096-3255158 (Counterclockwise)

Preceding gene: 78048419

Following gene: 78048417

Centisome position: 62.88

GC content: 63.68

Gene sequence:

>939_bases
ATGAGCGCGCGCATCCCCACGCTGGACATCACCCGTTTCGACACCGATCGCGACGCCTTCGTCGCCGAGCTCGGAGCGGC
TTATCGGCAGTGGGGTTTTGCCGGCATCCGCAACCACGGCATCGCCCAGGCCGACATCGACGCCGCCTACGACGTGTTCA
AGGCGTTCTTCGCGTTGCCCGAAGCGACCAAGCGCCGTTATCACGTGGAAGGCAGCGGTGGCGCGCGCGGCTACACCGCG
TTCGGCGTGGAAACCGCCAAGGATTCCAAGCACTTCGACCTGAAGGAGTTCTGGCACATCGGCCGCGAGATTCCGGACGA
TTCGCCGTACCGCGCAGTGATGCCGCCGAACCTGTGGCCCAGCGAAGTGCCGGGCTTCCGCGAGCGCGGCTACCAGCTGT
ACCAGCAGCTCGATCAACTGGGTTCGCGCGTGCTGTCGGCGCTGGCGCTGCATATCGGCCTGCCGCAGGACTACTTCGTC
GACAAGACCAACAACGGCAATTCGATCCTGCGGCCGATCCATTACCCGCCGATCACCAGCGACGACATTCCCAACGTGCG
TGCCGGTGCGCATGGCGATATCAATTTCATCACCTTGCTGGTGGGTGCCAGTGCCGCCGGCCTGGAAGTGCGTTCCCACG
ATGGCGAGTGGGTGCCGTTCACTGCCGACGCCGACACCATCGTGGTCAACATCGGCGACATGCTGCAGCGCCTGACCAAC
CATGTATATCCGTCCACCATCCACCGCGTGGTCAATCCGCCCGGAGAGCAGGCGCGCCAGCCGCGCTATTCGGTGCCGTT
CTTCCTGCATCCCAATCCGGATTTCCTCATCGACGTGCTGCCCTCGTGCATCAGCGCCGACAATCCCAGTCGTTATCCGG
AGCCGATCACGGCGCATGGCTTCCTGGAAGAGCGTCTGCGCGAGATCAAGCTGAAGTGA

Upstream 100 bases:

>100_bases
GTGGTCATCGCCAAGGCCGCCACGTTCTACCTGTTGTATCGCCTGCTGATCTGATCAGCAGGTTTCTCTGGACCTTTCGA
CCTTGACTGCAGACATCCGT

Downstream 100 bases:

>100_bases
TCTGCGCGCCTGCCCAACAGCCGCGCTCGCAACACCACCGGTGACCGGTGCCGCACTTCTGTTCAGAAGATTCCGCTCGC
GTCTGGTTAAAGCTTGCGTT

Product: putative 2OG-Fe(II) oxygenase superfamily protein

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSARIPTLDITRFDTDRDAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYDVFKAFFALPEATKRRYHVEGSGGARGYTA
FGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWPSEVPGFRERGYQLYQQLDQLGSRVLSALALHIGLPQDYFV
DKTNNGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSHDGEWVPFTADADTIVVNIGDMLQRLTN
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK

Sequences:

>Translated_312_residues
MSARIPTLDITRFDTDRDAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYDVFKAFFALPEATKRRYHVEGSGGARGYTA
FGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWPSEVPGFRERGYQLYQQLDQLGSRVLSALALHIGLPQDYFV
DKTNNGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSHDGEWVPFTADADTIVVNIGDMLQRLTN
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK
>Mature_311_residues
SARIPTLDITRFDTDRDAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYDVFKAFFALPEATKRRYHVEGSGGARGYTAF
GVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWPSEVPGFRERGYQLYQQLDQLGSRVLSALALHIGLPQDYFVD
KTNNGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSHDGEWVPFTADADTIVVNIGDMLQRLTNH
VYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=269, Percent_Identity=30.1115241635688, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI85816264, Length=287, Percent_Identity=27.1777003484321, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 34919; Mature: 34787

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARIPTLDITRFDTDRDAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYDVFKAFFALP
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
EATKRRYHVEGSGGARGYTAFGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWP
HHHHCEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCC
SEVPGFRERGYQLYQQLDQLGSRVLSALALHIGLPQDYFVDKTNNGNSILRPIHYPPITS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEECCCCCCCCCC
DDIPNVRAGAHGDINFITLLVGASAAGLEVRSHDGEWVPFTADADTIVVNIGDMLQRLTN
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCCEEEEEHHHHHHHHHH
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHG
CCCHHHHHHHCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FLEERLREIKLK
HHHHHHHHHCCC
>Mature Secondary Structure 
SARIPTLDITRFDTDRDAFVAELGAAYRQWGFAGIRNHGIAQADIDAAYDVFKAFFALP
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
EATKRRYHVEGSGGARGYTAFGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMPPNLWP
HHHHCEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCC
SEVPGFRERGYQLYQQLDQLGSRVLSALALHIGLPQDYFVDKTNNGNSILRPIHYPPITS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEECCCCCCCCCC
DDIPNVRAGAHGDINFITLLVGASAAGLEVRSHDGEWVPFTADADTIVVNIGDMLQRLTN
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCCEEEEEHHHHHHHHHH
HVYPSTIHRVVNPPGEQARQPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHG
CCCHHHHHHHCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FLEERLREIKLK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3216857; 8639682 [H]