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The map label for this gene is nuoG [H]

Identifier: 78048403

GI number: 78048403

Start: 3239579

End: 3241813

Strand: Reverse

Name: nuoG [H]

Synonym: XCV2847

Alternate gene names: 78048403

Gene position: 3241813-3239579 (Counterclockwise)

Preceding gene: 78048404

Following gene: 78048402

Centisome position: 62.6

GC content: 65.46

Gene sequence:

>2235_bases
ATGAGCGCCCAACCAGTGAACCCGAACGTGCCACCGGACCATGTGACCGTCGAGATCGACGGCCAGAGTCTGGTCGTGCC
GAAGGGCTCGATGATCATCCAGGCGGCCGACAAGGCCGGCATCCCGATTCCGCGCTTCTGCTACCACGAGAAGCTGCCGA
TCGCGGCCAACTGCCGCATGTGCCTGGTCGATGTCGAAAAGTCGCCCAAGCCGTCGCCTGCCTGCGCCACGCCGGTGATG
GATGGCATGAAGGTCACTACGCGTAGCGAAAAGGCTTTGAAGTACCAGCGCAGCGTGATGGAATTCCTGCTGATCAACCA
CCCGCTGGACTGCCCGATCTGCGATCAGGGCGGCGAGTGCGAACTGCAGGACGTTTCGCTCGGTTACGGCCGTTCGGTCA
GCCGCTTCAACGAGCGCAAGCGGGTGGTGCCGGACGAGGACATCGGTCCGCTGGTTGCCACCGAGATGACCCGCTGCATC
CAGTGCACCCGTTGCGTGCGTTTCACCGCTGATATTGCCGGCACCTACGAGCTGGGCGGCATGTATCGCGGCGAGAACCT
GCAGATCGGCACCTACGACGGCAAGCCGCTGACCACCGAGATTTCCGGCAACGTCATCGACGTCTGCCCGGTGGGCGCGC
TGACCAACAAGGTGTTCCAGTTCCGCGCGCGTCCGTGGGAACTGATGGCGCGCGAATCGCTGGGTTACCACGATGCGATG
GGTTCGAACCTGTTCCTGCACGTGCGTCGTGGCGAAGTGCTGCGCACAGTGCCGCGTGAGAACGAGGCAGTCAACGAATG
CTGGCTCTCCGACCGCGACCGTTATTCGCATCAGGGCCTGTATGCCGAAGACCGTGCGGTCAAGCCGCTGAAGAAGGTTA
ACGGGCAGTGGACTGAAGTGAGCTGGGCCGAAGGTCTGGCCGCCGCCACGCAGATCCTGCGCGAAAACGCCGGCGATCAG
CTCGGCGTGTTGGTGCATCCGTCCACGTCCAACGAAGAAGGCGCATTGCTCGCGCGTCTGGCCGAAGGTCTGGGCAGCGG
CAACCTGGACCACCGTTTGCTCAACCGTGATTTCTCCGACGCTGCGGTAGCCGAAGCGTTCGCCACGCCGCTGGCGGAGA
TCGAACAGGCTGACGTGGTGGTGTTGTTCGGCACCAATGTGCGGCATGAGCTGCCGTTGCTGCATGCGCGTCTGCGCAAG
GCGCATATCCAGAACCGTACGCAGATTCACTCGGTCAACCCGGTCGACTTCGACTTCGCCTTCACCCAGGCCAGCCGCAC
CGTGGTGGCGCCGTCGCAGTTGGCGGGTGCACTGAGCGATGCGACCCTGCGCGATGCGGTCAAGGCTGCAAGCCGCGCCG
TGATCGTGGTCGGCGCGTTGGCCGAAAATCATCCGCAGGCTGCCGCGTTGCGTGCCGCCGCACGCGACTTTGCTGCCGCA
ACCGGCGCAGCATTGTGCCGCATCCCGCAAGGCGCCAATGCCGTGGGTCTGGTGGCGCAGGGCGTGCTGCCGACCGCGCG
CGATGTCGCCGGCATGCTGGCCCAGCCGCGTCAGGCGTACGTGCTGTACGGCATCGAGCCAGGCCTGGATTTTGCCGACG
CCGCCGCTGCACGCAGCGCGCTGGCAGGCGCCAAGGTGGTTGCCTTCAGCCAGTTCGCCTGTGCGCCGACGCGTGATGTG
GCCGATGTGATTCTGCCGATCGGTGCGTTGCCGGAGATCGATGCATCGCTGACCAATCTCGATGGCCGCGTGCAGACTGC
ACGTGCTGCTGGCCGTTTACCGGTCGAAGCGCGCGAGGGCTGGCGCGTGCTGCGTGCACTTGGCGGTGAACTGGGTCTGC
CCGGTTTCGAATTCATCGACCTGATCGGCCTGCGCGCCGGCATGCAGAACCGCAACGTGACGCCAACGGCGTCGGCGCAG
CCAGCGGCCGCCAGCAACGGGCTGGAAGTCGCTGCAACTGCGGCGATCTACCGCACCGATGCGGTGGTGCGTCGGGCCGC
TGCGCTGCAGTCGCATCCGCTCAACATCGCGCCGTGCGTGGCGATGCATCCGGAGCAGGCGACGCAGTTGCAGGTCCAGG
CTGGTCAGATGGTCAAGGTCGGTACCGATGCCGGTAAGGCAACGTTGCCGGTGGTGCTGGACAAGCGCGTCGCACCGGGC
ACGGTGTGGATCGAATCCGGCCATGGCGCAACCGCGCCGCTCGGTGCCGGTCGTGTAACGGTGGTGGCTGCATGA

Upstream 100 bases:

>100_bases
CATGGCCGATCCAAGGCTTCCTGCGCCAGTTCTGGGACGAGTTCGAGTACTACATCGTCAACGGTCGTTCGATCGTCGAT
ACGCAAGTCGGAGTGGCTGC

Downstream 100 bases:

>100_bases
ACGAATTGTTGTTGAACCTGGTCGACCCGTTGCACCAGTGGTTCCTGGGGCTGGGTGATGGTGGCGTGGTGCTGTGGTCG
GTATTGAAGATCCTGCTGAT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MSAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRMCLVDVEKSPKPSPACATPVM
DGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGECELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCI
QCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGQWTEVSWAEGLAAATQILRENAGDQ
LGVLVHPSTSNEEGALLARLAEGLGSGNLDHRLLNRDFSDAAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRK
AHIQNRTQIHSVNPVDFDFAFTQASRTVVAPSQLAGALSDATLRDAVKAASRAVIVVGALAENHPQAAALRAAARDFAAA
TGAALCRIPQGANAVGLVAQGVLPTARDVAGMLAQPRQAYVLYGIEPGLDFADAAAARSALAGAKVVAFSQFACAPTRDV
ADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREGWRVLRALGGELGLPGFEFIDLIGLRAGMQNRNVTPTASAQ
PAAASNGLEVAATAAIYRTDAVVRRAAALQSHPLNIAPCVAMHPEQATQLQVQAGQMVKVGTDAGKATLPVVLDKRVAPG
TVWIESGHGATAPLGAGRVTVVAA

Sequences:

>Translated_744_residues
MSAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRMCLVDVEKSPKPSPACATPVM
DGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGECELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCI
QCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGQWTEVSWAEGLAAATQILRENAGDQ
LGVLVHPSTSNEEGALLARLAEGLGSGNLDHRLLNRDFSDAAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRK
AHIQNRTQIHSVNPVDFDFAFTQASRTVVAPSQLAGALSDATLRDAVKAASRAVIVVGALAENHPQAAALRAAARDFAAA
TGAALCRIPQGANAVGLVAQGVLPTARDVAGMLAQPRQAYVLYGIEPGLDFADAAAARSALAGAKVVAFSQFACAPTRDV
ADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREGWRVLRALGGELGLPGFEFIDLIGLRAGMQNRNVTPTASAQ
PAAASNGLEVAATAAIYRTDAVVRRAAALQSHPLNIAPCVAMHPEQATQLQVQAGQMVKVGTDAGKATLPVVLDKRVAPG
TVWIESGHGATAPLGAGRVTVVAA
>Mature_743_residues
SAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRMCLVDVEKSPKPSPACATPVMD
GMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGECELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCIQ
CTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAMG
SNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGQWTEVSWAEGLAAATQILRENAGDQL
GVLVHPSTSNEEGALLARLAEGLGSGNLDHRLLNRDFSDAAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRKA
HIQNRTQIHSVNPVDFDFAFTQASRTVVAPSQLAGALSDATLRDAVKAASRAVIVVGALAENHPQAAALRAAARDFAAAT
GAALCRIPQGANAVGLVAQGVLPTARDVAGMLAQPRQAYVLYGIEPGLDFADAAAARSALAGAKVVAFSQFACAPTRDVA
DVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREGWRVLRALGGELGLPGFEFIDLIGLRAGMQNRNVTPTASAQP
AAASNGLEVAATAAIYRTDAVVRRAAALQSHPLNIAPCVAMHPEQATQLQVQAGQMVKVGTDAGKATLPVVLDKRVAPGT
VWIESGHGATAPLGAGRVTVVAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=617, Percent_Identity=39.0599675850891, Blast_Score=410, Evalue=1e-114,
Organism=Escherichia coli, GI145693161, Length=385, Percent_Identity=29.8701298701299, Blast_Score=204, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17565758, Length=633, Percent_Identity=37.1248025276461, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI32566231, Length=593, Percent_Identity=37.6053962900506, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI193209088, Length=257, Percent_Identity=54.863813229572, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24640559, Length=655, Percent_Identity=38.3206106870229, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24640557, Length=655, Percent_Identity=38.3206106870229, Blast_Score=400, Evalue=1e-111,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 79229; Mature: 79098

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRM
CCCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHCCCCCEECCCEE
CLVDVEKSPKPSPACATPVMDGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGEC
EEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCIQCTRCVRFTADIAGTYELGG
EEEEECCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
MYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
EEECCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHCC
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGQWTEV
CCCEEEEEECCCHHHCCCCCCHHHHHHHCCCCCHHHCCCCCCCCHHHCHHHHCCCCEEEE
SWAEGLAAATQILRENAGDQLGVLVHPSTSNEEGALLARLAEGLGSGNLDHRLLNRDFSD
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCH
AAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRKAHIQNRTQIHSVNPVDFDFA
HHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
FTQASRTVVAPSQLAGALSDATLRDAVKAASRAVIVVGALAENHPQAAALRAAARDFAAA
EECCCCEEECHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
TGAALCRIPQGANAVGLVAQGVLPTARDVAGMLAQPRQAYVLYGIEPGLDFADAAAARSA
CCHHEEECCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
LAGAKVVAFSQFACAPTRDVADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREG
HCCCEEEEEHHHCCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCEEHHHHCCCCCCHHHHH
WRVLRALGGELGLPGFEFIDLIGLRAGMQNRNVTPTASAQPAAASNGLEVAATAAIYRTD
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHH
AVVRRAAALQSHPLNIAPCVAMHPEQATQLQVQAGQMVKVGTDAGKATLPVVLDKRVAPG
HHHHHHHHHHCCCCCEECEEEECCCCHHEEEEECCCEEEEECCCCCEEECEEEECCCCCC
TVWIESGHGATAPLGAGRVTVVAA
EEEEECCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRM
CCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHCCCCCEECCCEE
CLVDVEKSPKPSPACATPVMDGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGEC
EEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCIQCTRCVRFTADIAGTYELGG
EEEEECCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
MYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
EEECCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHCC
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGQWTEV
CCCEEEEEECCCHHHCCCCCCHHHHHHHCCCCCHHHCCCCCCCCHHHCHHHHCCCCEEEE
SWAEGLAAATQILRENAGDQLGVLVHPSTSNEEGALLARLAEGLGSGNLDHRLLNRDFSD
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCH
AAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRKAHIQNRTQIHSVNPVDFDFA
HHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
FTQASRTVVAPSQLAGALSDATLRDAVKAASRAVIVVGALAENHPQAAALRAAARDFAAA
EECCCCEEECHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
TGAALCRIPQGANAVGLVAQGVLPTARDVAGMLAQPRQAYVLYGIEPGLDFADAAAARSA
CCHHEEECCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
LAGAKVVAFSQFACAPTRDVADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREG
HCCCEEEEEHHHCCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCEEHHHHCCCCCCHHHHH
WRVLRALGGELGLPGFEFIDLIGLRAGMQNRNVTPTASAQPAAASNGLEVAATAAIYRTD
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHH
AVVRRAAALQSHPLNIAPCVAMHPEQATQLQVQAGQMVKVGTDAGKATLPVVLDKRVAPG
HHHHHHHHHHCCCCCEECEEEECCCCHHEEEEECCCEEEEECCCCCEEECEEEECCCCCC
TVWIESGHGATAPLGAGRVTVVAA
EEEEECCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]