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The map label for this gene is pheS [H]

Identifier: 78048347

GI number: 78048347

Start: 3171926

End: 3172921

Strand: Reverse

Name: pheS [H]

Synonym: XCV2791

Alternate gene names: 78048347

Gene position: 3172921-3171926 (Counterclockwise)

Preceding gene: 78048348

Following gene: 78048346

Centisome position: 61.27

GC content: 64.56

Gene sequence:

>996_bases
ATGAGTGAGATTCAATCCCTGACCGAGCGCGCGCTGGCCGATGTTGCCGCGGCGCAGACGCCGGACCAACTGGAAGCCTT
GCGTGTTGCATTGCTGGGCAAGAGCGGCAGCATCACTGCCCAGCTCAAGCAGCTCGGGACGTTGCCGGCAGAGCAACGCA
AGGCGGCTGGCGAGGCGATCAACCTGTCGCGCGACGCGCTGACTGCAGCGCTGGCCGAGCGCAAGCACACGCTGGAAACC
GCCGCGCTGGATGCCCGTCTTGCCGGCGAACGCATCGACGTCACCTTGCCGGGGCGTCGAAGCGAACGCGGCGGTCTGCA
CCCGGTGACACGCACGCTGGAGCGCATCGTCGAAATCTTCGCGCGGCTCGGCTACGAGCTGTCGGACGGCCCGGAGATCG
AGGACGACTGGCACAACTTCGAAGCCCTGAACTTTCCGCCGCATCATCCGGCGCGCGCGATGCACGACACGTTCTATTTC
GGCGACGGACGCCTGCTCCGCACACATACCTCAGGCGTGCAGGTGCGTTACATGGACGCGCACAAACCGCCGCTGCGCAT
GATCGCGGCCGGCAAGGTGTACCGCTCCGATTCGGATCAGACCCACTCGCCGATGTTCCATCAGGTCGAAGGCCTGTTGG
TGGACGAGCATTCCAATTTCGCCGACCTCAAGGGCACCTTGTCCGAGTTCGTGCGTGCGTTCTTCGAGCGCGATTTCGAA
ATGCGCTTCCGTCCCAGCTATTTCCCGTTCGTGGAGCCTGGCGCGGAAGTGGATATCGCCTGGCAGCAGCCCGACGGCAG
CACGCGCTGGCTGGAAGTGCTGGGCTGCGGCATGGTGCACCCGAATGTGCTGCGCAGCGTCGGCATCGACCCTGAGCGCT
ACACCGGCTTCGCCTTCGGCCTGGGCGTGGAGCGCTTCGCGATGCTGCGCTATGGCGTCAACGACCTGCGCGCGTTCTTC
GAGAACGATGTGCGTTTTCTTCGGCAGTTTGCTTGA

Upstream 100 bases:

>100_bases
TAGCGAAGTCGCCAAGTGGGCGATGACAGGTCAATGCAGTGACAATGCGTTCCGGTGTATCCGGAAACACCGTTCGGCTA
GCAGTTGAGGCGCAAGTGCA

Downstream 100 bases:

>100_bases
CGGCGGGGAGTCGGGAATTGGGAATCGGGAATCGCAAGAGCCATTGGCTCCATCGGTCCGGTTCCGAAGGCCCGGCAACC
CTGCTCTTGCGATTCCCCAT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSEIQSLTERALADVAAAQTPDQLEALRVALLGKSGSITAQLKQLGTLPAEQRKAAGEAINLSRDALTAALAERKHTLET
AALDARLAGERIDVTLPGRRSERGGLHPVTRTLERIVEIFARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYF
GDGRLLRTHTSGVQVRYMDAHKPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFE
MRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFGLGVERFAMLRYGVNDLRAFF
ENDVRFLRQFA

Sequences:

>Translated_331_residues
MSEIQSLTERALADVAAAQTPDQLEALRVALLGKSGSITAQLKQLGTLPAEQRKAAGEAINLSRDALTAALAERKHTLET
AALDARLAGERIDVTLPGRRSERGGLHPVTRTLERIVEIFARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYF
GDGRLLRTHTSGVQVRYMDAHKPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFE
MRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFGLGVERFAMLRYGVNDLRAFF
ENDVRFLRQFA
>Mature_330_residues
SEIQSLTERALADVAAAQTPDQLEALRVALLGKSGSITAQLKQLGTLPAEQRKAAGEAINLSRDALTAALAERKHTLETA
ALDARLAGERIDVTLPGRRSERGGLHPVTRTLERIVEIFARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYFG
DGRLLRTHTSGVQVRYMDAHKPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFEM
RFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFGLGVERFAMLRYGVNDLRAFFE
NDVRFLRQFA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=283, Percent_Identity=31.8021201413428, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI4758340, Length=269, Percent_Identity=30.4832713754647, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1788007, Length=330, Percent_Identity=60.9090909090909, Blast_Score=423, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI32563657, Length=266, Percent_Identity=29.6992481203008, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508957, Length=266, Percent_Identity=29.6992481203008, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32566635, Length=243, Percent_Identity=32.9218106995885, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6321087, Length=274, Percent_Identity=30.6569343065693, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6325304, Length=273, Percent_Identity=27.4725274725275, Blast_Score=105, Evalue=8e-24,
Organism=Drosophila melanogaster, GI18858079, Length=267, Percent_Identity=31.8352059925094, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137424, Length=242, Percent_Identity=28.9256198347107, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37210; Mature: 37078

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIQSLTERALADVAAAQTPDQLEALRVALLGKSGSITAQLKQLGTLPAEQRKAAGEAI
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCCHH
NLSRDALTAALAERKHTLETAALDARLAGERIDVTLPGRRSERGGLHPVTRTLERIVEIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMDA
HHCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHCEEEECCCEEEEEECCCEEEEEECC
HKPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFE
CCCCHHEEECCCEECCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCC
MRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFG
EEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHHCCCHHH
LGVERFAMLRYGVNDLRAFFENDVRFLRQFA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEIQSLTERALADVAAAQTPDQLEALRVALLGKSGSITAQLKQLGTLPAEQRKAAGEAI
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCCHH
NLSRDALTAALAERKHTLETAALDARLAGERIDVTLPGRRSERGGLHPVTRTLERIVEIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMDA
HHCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHCEEEECCCEEEEEECCCEEEEEECC
HKPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFE
CCCCHHEEECCCEECCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCC
MRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFG
EEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHHCCCHHH
LGVERFAMLRYGVNDLRAFFENDVRFLRQFA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA